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Biomedical subjects

M M Cotton

Publications and source records attributed to M M Cotton.

10 recordsLinked to original sources

Home treatment of exacerbations of chronic obstructive pulmonary disease by an acute respiratory assessment service.

BACKGROUND: Exacerbations of chronic obstructive pulmonary disease are a major cause of hospital admissions, but do not require intensive investigation or complex therapy. We investigated the suitability of home care for severe uncomplicated exacerbations. METHODS: Over 3.5 years we assessed 962 patients with exacerbations of chronic obstructive pulmonary disease after referral to a hospital respiratory department by their family physicians. All patients had chest radiographs, oxygen-saturation or arterial-gas analysis, spirometry, and physical assessment. Unless admission was thought to be essential, patients were allowed home with a customised treatment package. Each patient was visited daily by a respiratory nurse who monitored progress and treatment compliance and provided education and reassurance. FINDINGS: 145 (15%) of 962 required admission at initial referral and 115 (12%) were admitted later. 653 (68%) patients were managed entirely at home and 49 (5%) were referred inappropriately. One patient died at home. All patients had severe disease with a mean forced expiratory volume in 1 s of 1.02 L and 395 (41%) had required hospital admission in the previous year. INTERPRETATION: After formal assessment in a hospital respiratory unit, many patients with exacerbations of chronic obstructive pulmonary disease can be treated at home by respiratory nurses.

Acute Disease

Parents' and children's expectations about Irlen (tinted) lenses.

Additional unpublished data are presented from a study by Cotton and Evans in 1990 on the use of Irlen (tinted) lenses as an intervention for 22 children with a reading disability. These data reinforce the earlier conclusion that the random facilitatory effects of the lenses are very likely attributional and motivational in nature.

Attitude

A review of the use of Irlen (tinted) lenses.

Helen Irlen identified a syndrome defined as 'scotopic sensitivity' which it was claimed could be responsible for the inability of some people to read fluently and the symptoms of which could be ameliorated by the wearing of prescribed coloured lenses. The literature to date presents a confused and inconsistent picture concerning the use of the lenses. The literature (much of which is unpublished and difficult to obtain) is critically reviewed. Recent experimental evaluations of the lenses do not support the use of the lenses as a useful intervention for children with reading disabilities.

Color

Successful overshadowing and blocking in hippocampectomized rats.

Overshadowing (Experiment 1) and blocking (Experiment 2) were investigated using a conditioned suppression paradigm in rats. Neither hippocampectomy nor cortical control lesions affected the extent to which a salient stimulus overshadowed a less salient one. Nor did the lesions affect the extent to which a stimulus that was highly correlated with shock overshadow a stimulus that was less well correlated with shock. Finally, the lesions did not alter the extent to which a previously reinforced stimulus blocked conditioning to another stimulus when both were presented as a reinforced compound stimulus. It is thus possible for hippocampectomized rats to show apparently normal overshadowing and blocking, at least under some testing conditions.

Animals