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Biomedical subjects

M M Alves

Publications and source records attributed to M M Alves.

25 records · Page 2Linked to original sources
PubMed1990

Magnetic resonance imaging in motor neuron disease.

Magnetic resonance imaging (MRI) of the brain was evaluated in 20 patients with motor neuron disease (MND) and in a control group of 11 healthy people. Bilateral increased signal areas of various sizes in the centrum semiovale, corona radiata, internal capsule, pedunculi of midbrain, pons, medulla and even in the frontal lobe, topographically related with the corticospinal tract, were found in 8 out of 20 patients. Three out of 4 patients with progressive bulbar paralysis and 5 out of 11 cases of amyotrophic lateral sclerosis had abnormal MRI. Such MRI abnormalities have neither been found in patients with progressive muscular atrophy nor in controls, suggesting that they may be the hallmark of pyramidal tract degeneration in motor neuron disease.

Adult↗
PubMed1988

Propranolol or endoscopic sclerotherapy in the prevention of recurrence of variceal bleeding. A prospective, randomized controlled trial.

Endoscopic sclerotherapy (ES) and continuous propranolol (P) treatment have both been proposed as useful methods to prevent recurrent esophageal variceal bleeding. We report a prospective randomized trial in 65 patients with a previous history of endoscopically proven esophageal variceal bleeding. Patients were randomized by sealed envelopes stratified for Child's A and B groups to receive either endoscopic sclerotherapy (n = 31) or propranolol (n = 34). The dose of oral propranolol was based on a reduction of the resting pulse rate by 25%. Intravascular ethanolamine oleate was used for the endoscopic sclerotherapy in a 3-week schedule. The follow-up period ranged from 17 to 57 months (median: ES = 31; P = 28 months). There was no difference in the cumulative percentages of patients free of rebleeding from any source: esophageal and gastric varices, acute esophageal and gastric ulcers or erosions (ES = 37%; P = 16%). Also, there was no difference in the cumulative survival (ES = 69%; P = 54%). However, patients in the propranolol group had significantly more variceal rebleeding from the esophagus (n = 21) than did those in the sclerotherapy group (n = 9). The cumulative percentages of patients free of esophageal variceal rebleeding after inclusion were 67% in the endoscopic sclerotherapy group and 25% in the propranolol group (log-rank test, P less than 0.02). These differences indicated that sclerotherapy should be used in 29% of the propranolol patients who rebled. Based on these results we recommend elective sclerotherapy as long-term therapy for preventing rebleeding of esophageal varices.

Adult↗
PubMed1983

Rhythm of development in the oocyte of the tilapia Oreochromis niloticus L. (Pisces: Cichlidae); a morphometric and histochemical study.

The ovary of the tilapia Oreochromis niloticus was studied morphologically and morphometrically; the zonas granulosa and radiata, the ooplasm and the yolk globules were studied histochemically. The ovary is of typical teleostean type consisting of a wall and developing oocytes. The development of oocytes has been divided into 10 cytological stages. Histochemically the zona radiata and yolk globules contain glycoprotein (neutral mucopolysaccharides and protein radicals alpha-amino groups, cystine, cystein, tyrosin, tryptophane, and arginine. The zona granulosa and ooplasm contain neutral and carboxylate acid mucopolysaccharides and protein radicals alpha-amino group, cystein, cystine, tyrosin, arginine, and tryptophane.

Animals↗
PubMedDate not supplied

Hepatitis B virus surface antigen (HBsAg) and antibody (anti-HBs) forming immune complexes in fulminant hepatitis.

This paper reports an unusual pattern of serological HBV markers and the presence of HBsAg/anti-HBs immune complexes in serum samples from two patients with fulminant hepatitis from the Brazilian Western Amazon Basin. The diagnosis was made by both serologic tests and demonstration of antigen/antibody complexes by transmission electron microscopy. Concurrent Delta virus superinfection is also discussed.

Antigen-Antibody Complex↗
PubMedDate not supplied

[Endoscopic sclerosis for hemorrhage caused by peptic ulcer: a real advance].

The new methods of endoscopic hemostasis for bleeding gastric or duodenal ulcers are discussed. These techniques are increasingly important in patients with high risk for surgery. Due to its low cost, technical simplicity and a success rate similar to the other methods, endoscopic sclerosis is probably the first choice therapy for these conditions.

Duodenal Ulcer↗