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Biomedical subjects

M Lewis

Publications and source records attributed to M Lewis.

At least 577 records · Page 32Linked to original sources
PubMed1976

The Diego blood groups: a genetic linkage analysis.

Data are presented which show that the Diego blood groups are not part of the Dombrock or Yt blood group systems and that the locus controlling Di is not closely linked to the loci controlling ABO, Fy, Jk, Kell, MNSs, Rh, Gm, Inv, AcP,ADA, PGD, and UMPK.

Alleles↗
PubMed1976

Infants' responses to strangers: midget, adult, and child.

Infants respond differentially, and at times with fearlike behavior, to unfamiliar persons. This study was designed to see how infants discriminate among strangers. Since it has been shown that infants respond differently to children and adults, the physical characteristics of persons used to make such differentiations were of interest. Facial configuration and height were systematically varied as 4 different strangers--a male and female child, a female adults, and a small female adult the same height as the children (midget)--each approached 40 different infants. The infants responded as if there were 3 classes of persons--adult, child, and small adult, suggesting that both size and facial configuration cues were used. Infants as young as 7 months of age reacted to the size-facial configuration discrepancy of the small-adult condition.

Adult↗
PubMed1975

Treatment of deep-vein thrombosis with intermittent streptokinase and plasminogen infusion.

17 consecutive patients who presented with extensive deep-vein thrombosis, confirmed by phlebography, were included in this study. Of 12 patients who received streptokinase and plasminogen infusion, complete lysis of thrombi was obtained in 8 and partial but extensive lysis in 4. In contrast, thrombi remained unchanged in each of 5 patients who received the same doses of streptokinase infusion only.

Adult↗
PubMed1975

Arsine toxicity aboard the Asiafreighter.

Eight sailors on board the Asiafreighter were exposed to arsine that had escaped from a cylinder in the cargo hold. Four suffered severe toxicity and within a few hours had developed fever, weakness, nausea, vomiting, diarrhoea, abdominal pain, and haemoglobinuria. These patients had pronounced intravascular haemolysis, which in one patient was complete. This patient was also stuporose and anoxic, a condition attributed to failure of oxygen transport and sludging of red cell debris in the cerebral and pulmonary circulations, but he regained a normal level of consciousness after exchange transfusion. Evidence of marrow depression was present: the reticulocyte response to the haemolysis was poor and there was a thrombocytopenia. All four patients developed renal failure, one being totally anuric for five weeks. Two patients developed peripheral neuropathy, and one was still severely disabled six months after the incident. The other four patients had a similar, though less severe, illness.

Acute Kidney Injury↗
PubMed1975

The use of saline-washed frozen red cells for extracorporeal bypass.

The use of saline-washed frozen red cells and homologous whole blood during cardiopulmonary bypass was compared in two groups of patients with similar medical disease, sex, age, pump time, types of operation, and surgical techniques. A technique for using saline-washed frozen red cells for cardiopulmonary bypass with no increase in hemolysis is described. Increased platelet counts were present at the end of bypass in the patients who were given frozen cells. The availability and the many advantages of frozen cells, such as improved oxygen transport and the absence of homologous blood reactions and viral infections, make them the preferred cellular blood component for use during open-heart operations.

Blood Cell Count↗
PubMed1975

Parallel changes in puffing activity and patterns of protein synthesis in salivary glands of Drosophila.

The changes in protein synthesis of salivary glands of Drosophila resulting from a brief exposure at 37 degrees have been analyzed on sodium dodecyl sulfate--acrylamide gels. In D. melanogaster and D. hydei this treatment induces nine and six new puffs, respectively, in the polytene chromosomes. After 20 min treatment seven new proteins are synthesized by the glands of D. melanogaster and six by those of D. hydei as detected by [35S]methionine labeling. Other agents, e.g., recovery from anaerobiosis, induce the same puffs and the same proteins. The extent of protein induction and the degree of puff induction are related to the severity of the temperature treatment. The new proteins are detected after 10 min treatmene at 37 degrees and their synthesis is inhibited by actinomycin D. Actinomycin D added 5 min after the start of temperature treatment has little effect on subsequent protein synthesis. The induced proteins are not tissue specific. Electrophoretic differences of two proteins exist between D. melanogaster and D. simulans, encouraging attempts to map the proteins' gene loci and to test directly whether or not the puffs code for them.

Amanitins↗
PubMed1975

The treatment of adopted versus neglected delinquent children in the court: a problem of reciprocal attachment?

The authors investigated the discrepant treatment by a juvenile court of adopted versus neglected delinquents. Adopted delinquents received harsher dispositions in spite of the fact that neglected delinquents often faced more serious charges. The two groups are compared in terms of family structure and the criminal and psychiartic histories of their parents; none of these seems to account for the adoptees' harsher treatment. The authors hypothesize that an interplay of late adoption intrinsic vulnerabilities in the children, and weakness of parental bonds accounts for the differential outcomes.

Adolescent↗