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Biomedical subjects

M Levy

Publications and source records attributed to M Levy.

At least 613 records · Page 34Linked to original sources
PubMed1979

Absorption of orally administered digoxin after massive resection of the small bowel.

Digoxin absorption was studied in a patient after massive small bowel resection (with only 15 cm. of jejunum left) after mesenteric thrombosis. Oral administration of 0.25 mg. digoxin tablets resulted in therapeutic blood levels between 0.7 and 2.2 ng./ml. Measurement of the urinary excretion of the drug in steady state revealed more than 80% of the maintenance dose. Renal digoxin clearance was 125 ml./min. This resulted in slowing of the heart rate from 120 to 80/min. with no side-effects. It is thus concluded that total absorption of digoxin might be normal in a patient with only 15 cm. of jejunum and that usual dogs of digoxin were sufficient for a therapeutic effect and "therapeutic" blood levels

Aged↗
PubMed1979

[Problems encountered by the anesthetist-intensive care specialist during aorto-coronary bypass surgery].

The authors studied a series of 288 patients undergoing surgery for aorto-coronary bypass. The anaesthetic protocol and operative protocol are described and particular emphasis is placed upon the aortic clamp time. Mortality and peri-operative complications are then analysed. The treatment of such complications is based essentially upon vasodilators and where necessary intra-aortic counter-pressure balloon device to provide circulatory assistance.

Anesthesia↗
PubMed1978

Relationship between diazepam dose, plasma level, age, and central nervous system depression.

Patients undergoing elective cardioversion for treatment of arrhythmias were premedicated with diazepam. The dose was individualized to achieve a degree of central nervous system CNS) depression characterized by response to painful but not vocal stimulation. Promptly following each cardioversion, blood was drawn and the plasma diazepam concentration was measured by gas chromatography. The plasma levels varied as widely as the diazepam doses so that there was no fixed plasma level of diazepam associated with the degree of CNS depression produced in these patients. However, both the dose of diazepam and the resulting plasma level were inversely correlated to age, indicating that age is a critical factor in the use of diazepam for cardioversion premedication; elderly are more sensitive to the depressant effects of this drug than the young.

Adult↗
PubMed1978

The verbal helping skills of trained and untrained human service paraprofessionals.

The verbal helping skills of human service paraprofessionals in a youth service agency were studied. Workers who had previously completed a 10-week systematic training program in basic helping skills were compared to untrained volunteer staff. Using simulated helping interviews, it was found that training made a significant impact on trainees' verbal helping responses. Skill level was maintained at a 2-month follow-up for certain responses whereas others returned to pretraining levels. Trainees were found to use significantly more "helpful" responses than volunteers. The need for training even carefully selected paraprofessionals is discussed.

Adolescent↗
PubMed1978

Carpal tunnel syndrome due to thrombosed persisting median artery. A case report.

Surgical intervention for carpal tunnel syndrome in a seventy year old woman revealed thrombosis of a double persisting median artery. The persisting median artery is a rare anomaly and its association with a thrombotic process to cause carpal tunnel syndrome is even rarer. Carpal tunnel syndrome is a widely-known phenomenon about which much has been written in the medical literature. A persisting median artery accompanying the nerve into the carpal tunnel is uncommon, occurring in only about 10% of such cases (Pecket, 1973) and thrombosis of such an artery as a cause for carpal tunnel syndrome is very rare (Burnham, 1963; DeAbreu & Godoy Moreira, 1958). We describe a case in which thrombosis is a double persisting median artery was discovered to be the cause of carpal tunnel syndrome at operation.

Aged↗
PubMed1978

Triceps tendon avulsion with or without fracture of the radial head--a rare injury?

The rarity of triceps tendon avulsion is called into question by our series of 6 cases collected over a 5-year period in a small, isolated Israeli community. The even rarer occurrence of triceps avulsion accompanying fractures of the radial head is more obviously contradicted by the 3 or 4 instances of such combined injuries in our series. Awareness that a fall on the outstretched arm, with or without fracture of the radial head, is sufficient cause of the triceps avulsion or tear ought to increase the frequency of the diagnosis. Just as fractures of the proximal ulna oblige the clinician to look for dislocations of the radial head (Monteggia or Hume fractures) (6), so must falls on the outstretched arm bring to mind the possibility of triceps tendon tears. Seemingly trivial findings then become significant, and the clinical entity thus crystallizes into the diagnostic syndrome.

Adult↗
PubMed1978

Inability of glucagon to increase glomerular filtration rate in dogs with experimental cirrhosis and ascites.

In marked contradistinction to the normal dog, to the dog with renal hypoperfusion, or to the chronic caval dog with ascites, the intravenous infusion of glucagon at 5 microgram/min to dogs with experimental portal cirrhosis and ascites does not increase glomerular filtration rate or renal blood flow. In eight experimental dogs who did not respond to glucagon, a marked natriuresis was observed in response to furosemide and a marked renal vasodilator response was seen following the intraarterial infusion of acetylcholine. Because plasma immunoreactive glucagon levels are increased fivefold in cirrhotic dogs, it is suggested that continuous high levels of this peptide render the animals insensitive to the effects of an exogenous infusion.

Animals↗