Search PubMed⌕ Search

Biomedical subjects

M Lepage

Publications and source records attributed to M Lepage.

53 records · Page 3Linked to original sources
PubMed1975

[The effect of unsaturated fatty acids on the lipoprotein composition of rats].

Young male rats of the Long-Evans strain were fed 10% lard or corn oil diets for 4 weeks. Analysis of plasma cholesterol showed a decrease of 22%; a decrease of the same order of magnitude as also observed in the lipoproteins, particularly in the VLDL fraction, with the unsaturated diet. Plasma triglycerides were reduced by 50%; their fatty acids were found to contain a higher proportion of linoleate and arachidonate. Cholesterol ester of the HDL fraction contained mostly arachidonate which increased significantly with the substitution of corn oil to lard. Analysis of the lipoproteins indicated a reduction in VLDL and an increase in HDL with the unsaturated diet, whereas LDL remained unchanged.

Animals↗
PubMed1971

Changes in Lipid Composition during Greening of Etiolated Pea Seedlings.

After 7 days of germination in the dark, the three sections of pea seedlings studied (cotyledons, stems, and young leaves) are rich in linoleic acid; after illumination of the seedlings a very significant increase in linolenic acid is observed in the young leaves section, whereas only small variations are noted in the fatty acid composition of the other sections. The increase in linolenic acid results from the increase in galactolipid content of the young leaves; these already linolenic acid-rich galactolipids are present but only in small amounts in the etiolated seedlings (10% of total lipid).Variations in composition of the other lipid classes (phospholipids and neutral fats) were also studied. The possibility of fatty acid transport from the cotyledons toward the young leaves during the synthesis of the photosynthetic apparatus is discussed.

Journal Article↗
PubMedDate not supplied

Pax6 expression patterns in Lampetra fluviatilis and Scyliorhinus canicula embryos suggest highly conserved roles in the early regionalization of the vertebrate brain.

We report expression patterns of the Pax6 gene in the dogfish Scyliorhinus canicula and the lamprey Lampetra fluviatilis during neurulation and at the beginning of organogenesis. At the stages studied, both genes display very similar expression domains in the dorsal forebrain, with a sharp posterior boundary at the diencephalon-mesencephalon border, in the hindbrain, excluding the floor plate and the roof plate, and in the spinal cord. The comparison of these expression patterns with those reported in osteichthyans suggests that the roles played by Pax6 in early brain regionalization have been highly conserved during vertebrate evolution.

Animals↗