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Biomedical subjects

M Lancet

Publications and source records attributed to M Lancet.

At least 55 records · Page 3Linked to original sources
PubMed1987

Characterization of the growth-discordant twin.

A computer-assisted analysis of perinatal variables was undertaken in order to characterize the growth-discordant twin. We studied 124 twin pairs grouped at four degrees of discordancy: over 5, 10, 15, and 20% birth weight difference, using the larger twin as 100%. Twins with birth weight discrepancy below these figures were considered concordant. Highly discordant second twins showed significantly lower birth weight, gestational age, and Apgar scores, and prolonged neonatal hospitalization, as compared with discordant first twins. Complex presentations and a higher cesarean section rate characterize discordant first and concordant twins. It is suggested that a 15% birth weight discordancy be used as the safety limit for birth weight disparity. We also recommend special attention when discordancy seems to increase, especially if the discordant is the second twin.

Adult↗
PubMed1986

Indications and results of metroplasty in uterine malformations.

During 14 years, 430 women with some type of congenital uterine malformation were discovered by different methods, with a rate of 1 in 137 deliveries. In only 17 was metroplasty indicated, because of very poor reproductive performance; out of 42 desired pregnancies, only 14.3% live births resulted. The abortion rate was 65.2%, and there were 13% premature deliveries. The operations performed included the Strassmann type in 13, the Tompkins technique in three and the Jones operation in one. After the metroplasty, out of 27 completed pregnancies the rate of abortions fell in 14.8% (P less than 0.00003) and the rate of live births rose to 85.2% (P less than 0.00003). There is no doubt that when the indication for metroplasty is strictly imposed, the staff is well versed in the different types of operations and the treatment is done in a center which has acquired competence, the improvement in reproductive performance can be quite impressive.

Abortion, Spontaneous↗
PubMed1986

Constant ovulation on the side of an occluded tube treated with human menopausal gonadotropin.

We have presented the case of a woman with unilateral occlusion of a tube ovulated permanently on the same side. The other ovary and tube were intact. To overcome this problem, we gave full menotropic treatment to induce super-ovulation, and the patient became pregnant in the second treatment cycle. We think medical treatment should be attempted before paradoxical oophorectomy is contemplated in women with unilateral occlusion who cannot become pregnant.

Adult↗
PubMed1986

Face presentation.

The diagnosis, aetiology, management and outcome of face presentation were analyzed in 51 cases. Primigravidas accounted for 17.6%, multiparas for 54.9% and grand multiparas (5 deliveries or more) for 27.5%. Prematurity did not appear to be an important aetiologic factor. The position was mentum anterior in 26 patients (51%), all but one of whom were delivered vaginally. Of 12 fetuses in the mentum transverse position, 11 were delivered vaginally after spontaneous rotation to mentum anterior. Ten patients presented with mentum posterior; only 2 were delivered vaginally after spontaneous rotation. Three fetuses were diagnosed as face presentation during Caesarean section. The mean birth-weight of the infants who rotated from mentum posterior to mentum anterior was 3,425 +/- 35g, while that of those with persistent mentum posterior was 3,792 +/- 347 (p less than 0.01). Records of monitored fetal heart rate were available in 21 cases. Late decelerations and variable decelerations were recorded in 6 (28.5%). The incidence of Caesarean section was 25.5% compared to an overall incidence of 4.4% during the period of the study. Oxytocin was administered to 10 patients, and 7 of them were delivered vaginally. Early diagnosis of presentation and position, with close fetal surveillance may improve fetal outcome. In case of mento-posterior position, primary Caesarean section at term should be considered.

Adult↗
PubMed1986

Urinary retention caused by impaction of leiomyoma in pregnancy.

Complete urinary retention caused by incarceration of a retroverted gravid uterus or large fibroid uterus is a rare condition. The following case report illustrates the acute onset of urinary retention caused by the combination of a large leiomyoma and pregnancy. Total hysterectomy was performed. To the best of our knowledge, such a combination has not been reported previously.

Adult↗
PubMed1986

Ovarian carcinoma masquerading as ovarian hyperstimulation syndrome.

Two patients receiving ovulation-inducing drugs were found to have ovarian carcinoma. Since patients receiving such medication are prone to develop enlarged ovaries with or without the fully developed hyperstimulation syndrome, the diagnosis of ovarian tumors in such patients may be delayed or missed. It is therefore being suggested that an ovarian enlargement persisting for more than 4 weeks, or the finding of ovarian solid masses by sonography in patients receiving ovulation-inducing drugs, should lead to a thorough work-up for neoplasia, sometimes including even laparotomy.

Adult↗
PubMed1985

Idiopathic hypoparathyroidism with gestational diabetes.

A case of gestational diabetes complicating the pregnancy of a hypoparathyroid gravid patient is presented. Labor was induced by prostaglandin E2 vaginal tablets, but delivery was by cesarean section. Separate treatment of the two endocrinopathies was successful. After the induction of labor, hypocalcemia and hypoglycemia were seen, and they may have been caused by the prostaglandin E2.

Adult↗
PubMed1985

Prevention of premature labor by 17 alpha-hydroxyprogesterone caproate.

Eighty pregnant women at high risk of giving birth prematurely were divided randomly into two groups. Treatment with either 17 alpha-hydroxyprogesterone caproate, 250 mg by intramuscular injection once a week, or a placebo was given in a double-blind fashion. Imminent premature labor occurred in 29.0% of the treated group and in 59.4% of the control group (p less than 0.025). The rate of premature deliveries was also significantly lower in the treated group (16.1%) than in the control group (37.82%) (p less than 0.05). There were no cases of perinatal death or fetal malformations in either group. The mean birth weight of all infants of the treated group was significantly higher than in those of the control group (3111.9 +/- 905 gm versus 2680 +/- 813.4 gm, p less than 0.05). The results support treatment with progesterone caproate for the prevention of premature labor.

17-alpha-Hydroxyprogesterone↗