Biomedical subjects

M Lamy

Publications and source records attributed to M Lamy.

At least 343 records · Page 19Linked to original sources

PubMedDate not supplied

[Role of a surgical emergency department in the management of a disaster bringing a great number of patients with burns].

Definition of a disaster would follow prescriptions from the "International Trauma Foundation" (Brighton 1981, document A). This disaster may be: simple (where the structure of community remains intact), compound (where the structure of community and function of the community are disrupted). The classification of disasters is realized: by cause, by number of casualties, by nature of pathology, by time while cause operating, by time of rescue procedures at site, by affected area, by rural or urban location. Belgian legislation about disaster is described. Disaster related to major technological risks will be characterized by high probability of traumatic and burns injuries. The authors prepare medical responses to this eventually, defining the role of a "base hospital", the role of a medical team at site and the management of different groups of burned patients. Propositions are made to bring together actors of "disaster plan".

Burns↗

PubMedDate not supplied

Biochemical pathways of acute lung injury.

Complement fragments (C3, C3d, C5a), thromboxane B2 (TxB2), 6-keto-PGF1 alpha and immunoreactive trypsin (IRT) were measured in 98 patients at risk of developing the adult respiratory distress syndrome (ARDS): 53 multiple trauma, 28 abdominal surgery and 17 acute pancreatitis. Sixty-five of these patients developed ARDS: 30 multiple trauma, 19 abdominal surgery and 16 acute pancreatitis patients. Forty of the 65 ARDS patients and 9 out of the 33 non-ARDS patients died. Mean value of the C3d to C3 ratio was abnormal in both ARDS and non-ARDS patients. C5a-like activity was detected in 70 out of the 98 patients (49 ARDS and 22 non-ARDS patients). TxB2 abnormal values (greater than 100 pg . ml-1) were found in 70% of the patients, especially when sepsis occurred. No correlation could be made between abnormal 6-keto PGF1 alpha values and ARDS or sepsis. The mean peak IRT value was 675 micrograms . 1(-1) for ARDS patients and 274 micrograms . 1(-1) for non-ARDS patients (p less than 0.05). A firm correlation was also measured between IRT and sepsis (p less than 0.01). C5a-like activity was regularly detected soon after injury, while TxB2 and IRT tend to appear later in patients developing ARDS. Neither C3d/C3, nor C5a-like activity, nor TxB2, nor IRT are specific markers of ARDS, since they also appeared in severely ill patients who did not develop ARDS.

6-Ketoprostaglandin F1 alpha↗

PubMedDate not supplied