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Biomedical subjects

M Lüning

Publications and source records attributed to M Lüning.

At least 37 records · Page 2Linked to original sources
PubMed1989

[Computed tomographic false diagnoses in acute pancreatitis].

With computed tomography acute pancreatitis can be differentiated into an oedematous, serous-exudative, hemorrhagic-necrotizing, suppurative-abscessing and a postacute necrotizing form with high diagnostic accuracy (83.2%). Problems occur in distinguishing necrotizing from abscessing pancreatitis. False negative and false positive errors are less frequent in detecting necrosis and its differentiation from less serious forms (4.4% and 2.1%). Dynamic CT discovers also parenchyma losses not detectable without contrast medium and allows to prove subtotal or total necrosis in case of discrete changes in the native scans. Sonographic tomography contributes to diagnostics by proving acute necrotizing pancreatitis due to a chronic inflammatory pancreatic process.

Acute Disease↗
PubMed1989

[Experiences with CT-guided percutaneous drainage of pyogenic liver abscesses].

32 CT-guided percutaneous drainages of bacterial liver abscesses in 25 patients accomplished definitive sanitation in 18 of them (72%). In 7 cases surgical revision was required. Percutaneous drainage of abscesses was able to achieve a temporal improvement in these cases and therefore was an effective pre-surgical measure. There were no complications primarily due to the method itself. The average dwell-time of catheters during drainage of curative percutaneous drainage was 22.5 days. The new therapy concept has proven to be of little discomfort and complications together with high therapeutic effectiveness.

Adult↗
PubMed1989

[Experiences with intra-arterial tumor chemotherapy of malignant liver tumors via totally implantable catheter systems].

Locoregional chemotherapy was applied to 30 patients for isolated, surgically not removable liver tumours (13 colorectal carcinomas, 17 carcinomas on different sites). Ten patients were in Stage I, 16 in Stage II, and four in Stage III. Cytostatics were administered through totally implantable catheter systems. The following therapeutic protocol was mainly used: 5-flourouracil 800-1,000 mg/m2/3hr/die X 5 in 22 days, adriamycin 30 mg/m2/3 hr/die X 2 in 22 days. The average time of treatment amounted to ten months. Cytotoxis side effects were of minor importance. Hepatic side effects, such as chemical hepatitis or sclerosing cholangitis, were not recordable. Reduction of tumour size by 50 percent or more was recorded by computed tomography from 14 cases (46.6 percent). The objectivated rate of responsiveness in patients with colorectal carcinoma was 61.5 percent. The average period up to progression amounted to 12.1 months. Premortal spreading of the disease beyond the liver was recorded from six patients.

Antineoplastic Agents↗
PubMed1988

CT diagnosis of pedunculated liver tumours.

Liver tumours with extrahepatic location are uncommon. They show specific CT criteria with respect to blood supply. Various CT criteria have been analysed in 10 tumours, including three hepatocellular adenomas, two focal nodular hyperplasias, four cavernous haemangiomas and one hepatocellular carcinoma. Correct diagnosis was obtained only in haemangiomas with their characteristic hyperdense blood pools, and in one hepatocellular carcinoma. CT criteria of the ten pedunculated tumours are discussed, to with the aim of adding to our knowledge of the diagnostic relevance of CT.

Adenoma↗
PubMed1987

[Results of computed tomographic diagnosis in the grading of acute pancreatitis].

By means of computed tomography, it is possible to classify cases of acute pancreatitis into four grades of severity with reasonable accuracy: oedematous, sero-exudative, haemorrhagic-necrotic and abscess formation. Necrotic pancreatic tissue can be differentiated from normal tissue by means of dynamic computed tomography with a high degree of accuracy and the organ can be demarcated more clearly. Of 230 patients with acute pancreatitis, 89 were treated surgically. Correlation between the CT classification and surgical findings was achieved in 83% of the cases in the three serious grades. In 86 patients (96.6%, necrosis was correctly diagnosed. The problems that arise when trying to differentiate between the haemorrhagic-necrotic form and abscess formation are discussed, particularly when there is an absence of gas in the latter type.

Acute Disease↗
PubMed1987

[Results of treatment of pyogenic liver abscesses].

In the last 7 years 53 patients with liver abscesses were treated at surgical clinic of Charité. Since November 1982 we treated in 27 cases with solitary and multiloculary liver abscesses by percutaneous drainage of the abscess diameter more than 3 to 4 cm. 12 patients with multiloculary small biliary liver abscesses were treated by antibiotics. The bacteriological examination were performed after CT-supported puncture of the abscess. Seven patients with complicated abscesses could not be healed with CT-drainage. Surgical drainage via laparotomy was necessary. The diagnostic clarification of the dignity is important in every case. The lethality of all treated liver abscesses was 5.6% and the causes of death were the existing basic diseases.

Adolescent↗
PubMed1987

[Value of computerized tomography of the thorax in germinal testicular tumors].

Sporadic informations in the literature that by means of CT of the thorax by far smaller intrapulmonary foci can be recognized in comparison to the conventional x-ray examination are just to be confirmed. With the help of instances the indication for thorax CT in germinal testicular tumours is presented. The evidence and exclusion, respectively, of pulmonary metastases are of decisive importance actually for the therapy and prognosis in patients with germinal testicular tumours. In this respect our observations confirm the indications for a CT-examination of the thorax in these groups of patients.

Adult↗