Search PubMed⌕ Search

Biomedical subjects

M L Zhang

Publications and source records attributed to M L Zhang.

At least 55 records · Page 3Linked to original sources
PubMed1986

Microskin grafting. I. Animal experiments.

This article reports a new grafting technique--microskin grafting. These experiments were carried out in rabbits, and used a small amount of autograft minced into tiny pieces and then spread on a piece of homograft. The combined autograft plus homograft was then transplanted onto the wound of a rabbit. In 12 rabbits, the microskin grafts took well and covered the wound completely in 8 rabbits. The expansion ratios of the micrografts were from 7:1 to 15:1. The healing time of the wound was from 19 to 35 days. The operation failed in 4 rabbits because of the homograft moving. Histological sections revealed that microskin grafts orientated upwards can grow well and those orientated in a lateral or downward direction can grow too. This technique is an effective procedure for repairing extensive wounds with smaller donor sites.

Animals↗
PubMed1986

Microskin grafting. II. Clinical report.

A technique for microskin grafting for treating extensively burned patients is presented. Eight extensively burned patients were treated in this way with encouraging results. The recipient area covered by microskin grafts ranged from 2.5 per cent to 44 per cent of the total body surface area (TBSA). The expansion ratio of the micrografts was 15:1 maximum. The micrografts took well in seven patients with the healing time ranging from 22 to 45 days post-operatively. One case failed because of sloughing of the homograft. The advantages of the microskin grafting are: (1) economical use of autografts, (2) the procedure is simple, (3) there is less scar on the recipient site. This new technique is effective, simple and feasible in extensive burns.

Adult↗
PubMed1986

[Smoking and mortality in lung cancer].

From 1978 to 1980, a retrospective epidemiologic survey on mortality of lung cancer was undertaken in Taiyuan, an industrial city of Shanxi Province. The average crude mortality was 14.35/100,000, the third place in death of the malignancies. In the male the mortality was 20.46 ranking the second. In the female, it was 7.26, the fourth. It was increased markedly in the man over 35 years old and in the woman over 40. The death rate was higher in the urban districts than in the suburbs of the city. This difference was statistically significant (P less than 0.05). In the urban districts, suburbs of this city and its countryside, both the incidence and mortality showed significant differences in smoking and non-smoking groups (P less than 0.01). This result indicates that smoking is related to lung cancer. The mortality of malignant tumors was 176.69/100,000 in the smoking group, whereas in the non-smoking group, it remained at the level of 46.65/100,000. It should be further studied that how smoking exerts influence on the other malignancies. The relative risks (RR) of lung cancer to smoking were 3.07 in the male and 2.60 in the female with a total RR of 3.52. The data mentioned above suggest that cigarette smoking plays an important role in the cause of lung cancer. Hence, to advocate abstinence of smoking is of vital importance, especially in the industrial districts.

Adolescent↗
PubMed1985

Alpha-1-antitrypsin types in five Chinese national minorities.

The frequencies of alpha-1-antitrypsin alleles were determined for five Chinese national minorities: Uigur, Korean, Mongolian, Chuang, and Li. PI S and PI Z alleles are not found in the five populations studied. PI ETOK allele is present in Korean, Mongolian, and Chuang populations, and Etokyo is a very common alpha-1-antitrypsin variant in Chinese. Other alleles which occur in more than one of the minorities are PI X (Mongolian and Chuang) and PI M4 (Korean and Uigur). The high frequency of PI M4 in the Uigur population suggests a probably Occidental origin of this nationality.

Alleles↗
PubMed1985

Geographical variability of alpha-1-antitrypsin alleles in China: a study on six Chinese populations.

Alpha-1-antitrypsin phenotypes of six Chinese Han populations (20 degrees-45 degrees N. latitude) were determined. The frequency of allele M2 increases from North to South China. The north-south change of M2 appears to be mainly at the expense of alleles M1 and M3. Geographical variability of other variants was also observed. In the northern populations, the most common variants are M4 and Etokyo; in the southern populations, Pweishi, a variant which can not be distinguished electrophoretically from Pyasugi. These results form a distribution pattern of alpha-1-antitrypsin alleles in China.

Alleles↗
PubMed1985

Candida infection in severe burns.

Candida infection has become an important cause of morbidity and death in burned or immunosuppressed patients. Two patients with extensive burn complicated with Candida infection are presented, along with the risk factors, diagnostic procedures, and current methods of treatment.

Adult↗
PubMed1985

Frequencies of ceruloplasmin alleles in a Chinese population.

Plasma ceruloplasmin phenotypes were determined in a Chinese population. Among 1,042 unrelated persons examined, 3 appeared to be heterozygotes for an unidentified allele. Thus the frequency of the rare ceruloplasmin allele was estimated to be 0.0014.

Alleles↗
PubMed1984

PI*LBEI and PI*JHOU: two new alpha-1-antitrypsin alleles.

Two new variants of alpha-1-antitrypsin were found in a Chinese population by isoelectric focusing in polyacrylamide gel. They have been named Lbeijing (PI*LBEI) and Jhouyao (PI*JHOU) respectively. With the samples reduced and alkylated, both the variants were anodal to M1 and cathodal to L. Omitting the alkylation step, however, the relative mobilities of L and Jhouyao were altered. Under this condition, a characteristic of Jhouyao was revealed by isoelectric focusing in immobilized pH gradient 4.4-4.9, i.e., while its band 6 became anodal to L, band 4 was still cathodal to L.

Alleles↗