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Biomedical subjects

M L Sipski

Publications and source records attributed to M L Sipski.

30 records · Page 2Linked to original sources

Long-term use of computerized bicycle ergometry for spinal cord injured subjects.

Twenty-eight spinal cord injured subjects who participated in an electrical stimulation bicycle ergometry home program were surveyed to determine perceived benefits, home exercise adherence, and predictors of continued home exercise with electrical stimulation. Subjects were classified as users or nonusers depending upon if they used the electrical stimulation ergometry on a regular basis in the home during the past four months. Nineteen subjects qualified as users and nine were nonusers. Ninety-five percent of the users cycled at least twice per week whereas the majority of the nonusers stopped regular home exercise within one month postclinic discharge. All subjects generally perceived increases in muscle bulk and endurance. Users and nonusers perceived inconsistent results related to spasticity. Minimal effects were noted with neurogenic pain and swelling. Adherence to the home exercise program was significantly related to sex of subject and pre-injury exercise habits. Results are discussed in relation to the costs and benefits of electrical stimulation bicycle ergometry in the home.

Adolescent↗

Spinal cord injury: what is the effect on sexual response?

In this paper the sexual response cycle and neurologic pathways involved in sexual functioning are reviewed. This is used as a foundation to review the spinal cord injury literature and examine what is primarily self-reported regarding sexual function with varying types of spinal cord injury. A recommendation is made for more thorough, objective studies through which hypotheses can be tested and a foundation built for prognostication of how sexual functioning will be altered after varying types of SCI.

Ejaculation↗

The impact of spinal cord injury on female sexuality, menstruation and pregnancy: a review of the literature.

Spinal cord injury (SCI) results in alterations in sexual functioning. This area has been studied in depth in males; however, the literature pertaining to female sexual dysfunction after injury is sparse and focused primarily on menstruation and pregnancy. This report reviews the literature on female sexuality, menstruation and pregnancy after SCI and discusses the findings.

Breast Feeding↗

Rehabilitation of patients with spinal cord disease.

Spinal cord injury and disease have multisystem consequences and many potential medical complications. This article addresses the various medical, psychosocial, and vocational issues associated with spinal cord injury and describes how the patient's lifestyle may be affected. The role of the physician and other rehabilitation professionals in the rehabilitation process is described. In addition, various medical concerns, complications, and available treatment modalities are discussed.

Humans↗

Functional electrical stimulation bicycle ergometry: patient perceptions.

Forty-seven patients who had participated in a clinical electrical stimulation ergometry program were administered a questionnaire to determine their perceptions of the therapy. Improved endurance was reported by 62% of paraplegics and 65% of quadriplegics. Sixty-two percent of paraplegics and 56% of quadriplegics reported improved self-image, while 54% of paraplegics and 77% of quadriplegics perceived their appearance was better. Thirty-nine percent of paraplegics and 24% of quadriplegics noted decreased lower extremity edema with training. Six out of nine patients with a previous history of neurogenic pain noted an increase in pain, which caused them to leave the program.

Activities of Daily Living↗

Diaphragmatic dysfunction in siblings with hereditary motor and sensory neuropathy (Charcot-Marie-Tooth disease).

Hereditary motor and sensory neuropathy (Charcot-Marie-Tooth disease) is characterized by chronic degeneration of peripheral nerves and roots, resulting in distal muscle atrophy, beginning in the feet and legs and later involving the hands. The association of this disease with diaphragmatic dysfunction has not been reported. We studied a patient with hereditary motor and sensory neuropathy type 1 (Charcot-Marie-Tooth disease) and type 2 diabetes mellitus who had severe diaphragmatic impairment. Some of the clinical findings are similar to the sleep apnea syndrome, which could lead to incorrect diagnosis and delay in the administration of appropriate therapy. Transdiaphragmatic pressure studies on the subject's brother, who also has Charcot-Marie-Tooth disease and type 2 diabetes mellitus, revealed subclinical impairment of diaphragmatic function. These findings suggest that phrenic nerve involvement may be part of the spectrum of polyneuropathy in Charcot-Marie-Tooth disease in association with diabetes mellitus.

Aged↗

Wrist extensor recovery in traumatic quadriplegia.

Wrist extensor recovery is of major functional significance in many quadriplegic patients. In this retrospective study, we investigated a method for prognosticating wrist extensor recovery and the underlying mechanisms for improvement in strength. Thirty-five quadriplegic patients at the C4, C5, and C6 neurologic levels, admitted over a four-year period, were examined at one week, two months, and eight months postinjury for biceps and wrist extensor strength. Initial biceps strength was compared to final wrist extensor strength. All 16 C5 patients whose initial biceps strength was grade 3 showed wrist extensor improvement to grade 3; only three of 16 C4 patients showed the same improvement. We concluded that initial biceps strength is a reliable indicator of wrist extensor recovery, and most, if not all, C5 neurologic patients will gain one full motor level. This improvement may be due to compensatory factors, such as overwork hypertrophy and peripheral sprouting of nerves within the muscle, rather than to recovery of a root level.

Accidents↗

Sexual response in women with spinal cord injuries: implications for our understanding of the able bodied.

This study assesses the impact of psychogenic and reflex sexual arousal on women with complete and incomplete spinal cord injuries (SCIs) and explores the effects of SCI on orgasm in women. Thirty women with SCIs and 10 able-bodied women participated in the study. Three individual experiments were conducted over a 3-day period, assessing (a) the impact of SCI on psychogenic sexual arousal, (b) the impact of SCI on orgasm; and (c) the impact of SCI on reflex sexual arousal. Results support the hypothesis that women with complete SCIs and upper motor neuron injuries affecting the sacral spinal segments and women with incomplete upper motor neuron SCIs had the capacity for reflex lubrication. Women with SCIs were significantly less likely than able-bodied women to achieve orgasm. However, there was not a significant difference among women with different SCIs to achieve orgasm.

Adolescent↗

Alteration of immune system function in tetraplegics. A pilot study.

Over the past 20 yr, evidence has accumulated that implicates the autonomic nervous system as a central modulator of immune function. We hypothesized that injury to the cervical spinal cord would affect immune function by dysregulation of the sympathetic outflow tract. To test this hypothesis, peripheral blood lymphocytes were obtained from five individuals with complete cervical spinal cord injury (SCI) and from five age- and sex-matched neurologically intact controls. Immunologic parameters studied included cell counts by flow cytometry, lymphocyte proliferation response to three mitogens and a natural killer cell cytotoxicity assay. In addition the Ilfeld Psychiatric Symptom Index was completed by all subjects and controls. Repeated measures analysis of variance revealed an impaired lymphocyte proliferation response in the SCI group. Our results suggest that individuals who have sustained complete cervical SCI have alteration in immune function as compared with neurologically intact controls. This may contribute to infections after spinal cord injury. The mechanism may involve dysregulation of the sympathetic arm of the autonomic nervous system.

Adult↗