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Biomedical subjects

M L Seetharaman

Publications and source records attributed to M L Seetharaman.

12 recordsLinked to original sources

Effect of short course chemotherapy on salivary paracetamol elimination.

1. Salivary elimination of paracetamol was studied in six male pulmonary tuberculosis patients on short course chemotherapy. 2. Peak paracetamol concentration showed a steady decrease at the end of first week and continued until the end of the study. 3. The elimination half-life of paracetamol decreased 5 weeks after the therapy with a corresponding increase in the clearance rate. 4. Adjustment of dosage of drugs that are metabolized by the microsomal enzymes may be required in patients on anti-tubercular drug regimen in which rifampicin is included.

Acetaminophen↗

Haemoptysis.

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Clinical Protocols↗

Lung and HIV infection with special reference to tuberculosis: preliminary report on 20 HIV-1 seropositive cases.

The clinico-radiological profile of 20 patients with tuberculosis and other respiratory diseases infected with HIV-1 is presented in this preliminary communication. Twelve patients had proven and 4 had suspected tuberculosis. Two patients were diagnosed as having interstitial pneumonitis on limited autopsy. Five patients fulfilled the CDC's new AIDS definition criteria. Though our experience is limited, yet, in the present series, the patients with tuberculosis showed typical extensive upper zone infiltrative lesions. Patients with tuberculosis (pulmonary and extrapulmonary, excluding disseminated disease) showed improvement on short course regimens of anti-tuberculosis chemotherapy, without any toxic effects.

AIDS-Related Opportunistic Infections↗

Tuberculous mainstem bronchostenosis in a ten-year-old girl.

Tuberculous bronchostenosis involving the main bronchus is rare in children. We describe a 10-year-old girl who developed left mainstem tuberculous bronchostenosis inspite of effective and adequate chemotherapy for which she underwent a left pneumonectomy.

Bronchi↗