Search PubMed⌕ Search

Biomedical subjects

M L Pollock

Publications and source records attributed to M L Pollock.

At least 109 records · Page 6Linked to original sources

Coronary artery bypass patients and work status.

Retrospective surgery data were obtained from 358 coronary artery bypass surgery patients 4-22 months (mean 12.5 months) after surgery. Before surgery, 69% of the subjects were working, 10% were unemployed, and 21% were retired. At follow-up, only 58% were working and 29% were retired. Employment before surgery was the most significant predictor of work status after surgery. Other factors that were positively related to returning to work include higher presurgery income and job classification, higher pre- and postoperative ejection fraction, and subjective improvement in tolerance for physical activity. Factors that were negatively related to returning to work were age, number of chronic medical problems, presence of cardiac symptoms, and receipt of disability compensation. Reported improvement in symptoms was not related to postoperative work status. Job classification, physical demands of the job, and time out of work before surgery were also related to how soon patients returned to work. Participation in an outpatient rehabilitation program was significantly related to postoperative work status for men employed before surgery. Questions were raised regarding the role of outpatient cardiac rehabilitation in altering patient perceptions and maintaining "work habits" that might facilitate work resumption after coronary artery bypass surgery. The results suggest that multiple physical, social and psychological factors interact to influence postoperative work status.

Adult↗

Steps toward the development of generalized equations for predicting body composition of adults.

The estimation of body density from anthropometric variables is often used to measure body composition. The purpose of this report was to review the development of early published equations and follow the transition from population specific equations to generalized equations for adults. The accuracy of population specific equations were improved and refined with the addition of circumference and diameter measures in combination with skinfolds and the use of populations of varied ages and degrees of body fatness. The major weakness of the population specific equations was their inability to account for aging and the non linear relationship between subcutaneous fat and body density. Regression models using the quadratic sum of skinfolds and age have been developed to account for these sources of variation. Cross-validation research has shown that these generalized regression models are accurate for adult males and females varying greatly in age and body fatness.

Adolescent↗

Fifty years of training and competition in the marathon: Wally Hayward, age 70--a physiological profile.

A 70-year-old South African long-distance runner, holder of his age group's marathon record and former Olympic marathon runner, was studied to determine the effects of 52 years of regular training on functional capacity and health. Maximal treadmill exercise testing revealed no ischaemic ECG abnormalities and an excellent functional capacity (58,6 ml/kg/min). Submaximal testing showed that the subject ran at approximately 86% of maximum aerobic capacity when completing the marathon in his record time. The subject was very lean (13,6% fat) for his age. Muscles contained 82% slow-twitch fibres. Pulmonary function and blood chemical values were within normal limits. Although total cholesterol was somewhat high (247 mg/dl), high-density lipoprotein cholesterol was elevated (53 mg/dl). Twenty-four-hour Holter monitoring revealed no significant ventricular ectopic activity although frequent premature atrial contractions were noted. M-mode echocardiography revealed a normal heart with moderately hypertrophied left ventricular wall thickness. Radionuclide cine angiography showed a normal ejection fraction at rest (69%), followed by a slight drop at maximal exercise (62%). Left ventricular regional wall motion was considered normal at both rest and exercise. He had no significant orthopaedic abnormalities but showed normal flexibility and well-balanced muscular strength. Thickened heel pads were also noted. These results appear to indicate a beneficial effect of habitual physical activity upon the retention of functional capacity with ageing.

Aged↗

Left ventricular function during sudden strenuous exercise.

Strenuous exercise without warm-up has been shown to produce ischemia-like electrocardiographic (ECG) abnormalities in 60-70% of healthy subjects. These abnormalities appeared to be related to the development of an unfavorable myocardial supply/demand balance and, in chronically instrumented dogs, to transient decreases in coronary blood flow. A mechanism involving subendocardial ischemia has been proposed to explain the response to sudden strenuous exercise (SSE). To determine whether the response to SSE included the development of changes in myocardial pump performance typical of ischemia, left ventricular (LV) function at rest, during graded exercise and during SSE was evaluated in nine young (26.6 +/- 3.4 years), well-trained male volunteers using first-pass radionuclide angiography. During graded exercise, the LV ejection fraction increased from 66.9 +/- 9.4% at rest to 73.0 +/- 7.1% during peak exercise, and the LV ejection rate increased from 3.36 +/- 0.67 sec-1 at rest to 6.58 +/- 1.10 sec-1 during peak exercise. Segmental wall motion was normal in all studies. During SSE, the LV ejection fraction decreased in very subject, from an average 72.2 +/- 8.6% at rst to 57.3 +/- 8.1% during exercise. The LV ejection rate remained relatively constant (3.98 +/- 0.92 sec-1 at rest vs 4.33 +/- 0.74 sec-1 during SSE). No segmental wall motion abnormalities were observed during SSE; however, LV wall motion appeared to be diffusely hypokinetic during SSE. In contrast to previous reports, few ECG abnormalities were observed during SSE. These results support the hypothesis that subendocardial ischemia is an important mechanism in the response to SSE. However, the lack of ECG changes and segmental wall motion abnormalities and the relatively high absolute value of the LV ejection fraction suggest that if subendocardial ischemia occurs during SSE, it is attributable to physiologic rather than pathologic mechanisms.

Adult↗

Generalized equations for predicting body density of women.

Previous research with women has shown that body composition regression equations derived from anthropometric variables were population specific. This study sought to derive generalized equations for women differing in age and body composition. The hydrostatic method was used to determine body density (BD) and percent fat (%F) on 249 women in 18 to 55 years (X = 31.4 +/- 10.8 yrs) and 4 to 44 %F (X = 24.1 +/-7.2 %F). Skinfold fat (S), gluteal circumference (C) and age were independent variables. The quadratic form of the sum of three, four and seven S in combination with age and gluteal C produced multiple correlations that ranged from 0.842 to 0.867 with standard errors of 3.6 to 3.8 %F. The equations were cross-validated on a different sample of 82 women with similar age and %F characteristics. The correlations between predicted and hydrostatically determined %F ranged from 0.815 to 0.820 with standard errors of 3.7 to 4.0 %F. This study showed that valid generalized body composition equations could be derived for women varying in age and body composition, but care need to be exercised with women over an age of forty.

Adipose Tissue↗

Physiologic effects on adult men of circuit strength training and jogging.

The purpose of this study was to determine the effects of 8 weeks of circuit strength training (CST) followed by 8 weeks of jogging and then 8 weeks, of CST or jogging. During the final 8 weeks, the subjects were randomly assigned to either CST or jogging groups. The subjects (n=16, x age = 29 yrs) exercised 3 days/week. The strength training involved 2 circuits of reciprocal exercises using isokinetic devices with 10 to 15 repetitions/set and 30 seconds of rest between sets. The subjects jogged 3 miles/day during the jogging program. After the initial 8 weeks of CST, significant changes were found in treadmill performance time, maximum oxygen uptake (VO2max), maximum pulmonary ventilation (VEmax), body fat, total skinfold fat, fat weight, lean weight, isotonic bench and leg press, and isokinetic slow speed, fast speed, and power endurance measures. The jogging program elicited significantly greater changes in treadmill performance time and VO2max. Further reductions were found in total skinfolds and waist girth during the jogging program. Leg strength was maintained during jogging but upper body strength was reduced significantly. Physiologic levels were maintained during the final 8 weeks and showed no differences between the CST and jogging groups.

Adult↗

Generalized equations for predicting body density of men.

1. Skinfold thickness, body circumferences and body density were measured in samples of 308 and ninety-five adult men ranging in age from 18 to 61 years. 2. Using the sample of 308 men, multiple regression equations were calculated to estimate body density using either the quadratic or log form of the sum of skinfolds, in combination with age, waist and forearm circumference. 3. The multiple correlations for the equations exceeded 0.90 with standard errors of approximately +/- 0.0073 g/ml. 4. The regression equations were cross validated on the second sample of ninety-five men. The correlations between predicted and laboratory-determined body density exceeded 0.90 with standard errors of approximately 0.0077 g/ml. 5. The regression equations were shown to be valid for adult men varying in age and fatness.

Adolescent↗

A comparison of body fat determined by underwater weighing and volume displacement.

Two hydrostatic techniques, underwater weighing and water displacement, were used to determine body fat for 67 volunteer men between 25 and 61 yr of age (-/x=41 yr). All tests were administered in random order in the morning on the same day while subjects were in the postabsorptive state. Test-retest reliabilities for the underwater weighing and water displacement techniques were 0.995 and 0.96, respectively. The correlation between the two hydrostatic techniques was r=0.96. The mean percent fat determined by underwater weighing (-/x=20.1 +/- 6.4) and water displacement (-/x=19.4 +/- 6.1) were significantly different (t=28.16; df=65; P less than 0.001). These analyses showed that both techniques were reliable in measuring percent body fat, but produced slight systematic differences. Regression equations were provided to adjust for the difference.

Adipose Tissue↗

Analysis of physical fitness and coronary heart disease risk of Dallas area police officers.

Two hundred thirteen male police officers between 21 and 52 years of age volunteered to participate in a physical evaluation and conditioning program. Information concerning the physical fitness status and risk of coronary heart disease (CHD) of police officers were shown. Younger police officers (less than 30 years of age) were average in physical fitness levels and CHD risk compared to the population of the same age. Middle-aged police officers were shown to be lower in physical fitness levels and higher in CHD risk compared to their cohorts. The results from this investigation support the need for physical fitness and preventive medicine programs for police officers.

Adult↗

The effect of circuit weight training on strength, cardiorespiratory function, and body composition of adult men.

The purpose of this study was to determine the changes elicited by circuit weight training (CWT) and running (RN) programs conducted 3 days/week for 20 weeks. Subjects were randomly assigned to one of three groups: CWT (n = 11); RN (n = 16); and control (n = 14). CWT consisted of 10 exercises performed in 2 sets of 15 reps with 20 to 25 sec rest between exercises. CWT workout time decreased from 30 min to 23 min; exercise heart rate (HR) increased from 79% to 84% max; average weight increased from 42% to 56% of max 1 RM strength and total weight increased 81% (1506 to 2720 lbs/workout). The RN group exercised at 85% max HR for 23 to 27 min/workout. Multivariate and step-down analyses showed the CWT group to be significantly different from the control group at the end of 20 weeks in leg press strength, fat weight, and Vo2 max (1/min). The RN group was significantly different from the CWT group in Vo2 max and treadmill time. Univariate analyses revealed no differences between the CWT and control groups in Vo2 max expressed as ml/kg LBW.min but did show a significant superiority of the RN group over the other two groups in this variable. It was concluded that the CWT program was most specific in improving strength and changing body composition and produced only a small aerobic effect as measured on the treadmill running test.

Adult↗

Submaximal and maximal working capacity of elite distance runners. Part II. Muscle fiber composition and enzyme activities.

The present study confirms earlier observations that the musculature of elite distance runners is characterized by a high predominance of ST fibers. Although the percent ST fibers effectively discriminates between good and elite distance runners, fiber composition alone is a poor predictor of distance running success within the group of elite runners. Muscle enzyme measurements suggest that the 11 to 20 miles (17.7 to 32.2 km) of daily training performed by the elite runners produced a significantly greater increase in muscle SDH activity than was observed in the good distance runners, who were running 7 to 11 miles (11.3 to 17.7 km) per day, Although such endurance training enhances the oxidative capacity of the muscle, it apparently has little influence on the enzymes of glycogenolysis.

Energy Metabolism↗