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M L Druart

Publications and source records attributed to M L Druart.

26 records · Page 2Linked to original sources

[Isolated lesions of the gallbladder, in closed abdominal injuries. Apropos of 7 cases].

The authors report 7 cases of isolated injuries of the gallbladder, in closed abdominal trauma. The literature indicates the frequency to lie between one and five percent. The postprandial period and fasting alcohol levels, responsible for the distention of the gallbladder, are mostly the cause of such lesions. Four groups of injuries are described: 1) laceration 2) avulsion 3) simple contusion 4) traumatic cholecystitis Early diagnosis of such injuries is difficult as abdominal signs are poor and little specific; the authors note the value of peritoneal puncture and lavage. The treatment of gallbladder trauma is always surgical, cholecystectomy giving the best results; raphy and cholecystostomy are second choice treatments. The prognosis is usually favorable, even if surgery is delayed, and depends essentially on the nature of associated extra-abdominal injuries.

Adult↗

Influence of total parenteral nutrition (TPN) on some immune parameters in malnourished surgical patients.

Twenty-one protein-calorie depleted patients were given for one week total parenteral nutrition (TPN) including Intralipid during a sixteen months' period (September 1975 - December 1976). Before TPN, lymphocyte proliferation response to 1 microgram/ml of phytohemagglutinin (PHA) was abnormally low, while immunoglobulin levels were in the normal range. After one week of TPN, lymphocyte response to PHA was significantly improved in patients exhibiting positive nitrogen balance but remained unchanged in the others. Immunoglobulin IgA, IGG, IgM levels tended to rise in most of the patients, while IgE concentrations remained unchanged. Addition of Intralipid at various concentrations to lymphocyte cultures of both patients and normal volunteers did not effect 3H-thymidine incorporation in the lymphocytes. Similarly, in vivo infusion of Intralipid in normal subjects did not have any effect on lymphocyte performance. This study shows that: 1. effective TPN can correct some alterations in immune parameters; 2. Intralipid does not seem to have any effect on the parameters measured in the present work.

Adult↗