Has enterococcus to be regarded as pathogenic in biliary surgery? Comments on antibiotic prophylaxis using only one preoperative dose of ceftriaxone.
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Biomedical subjects
Publications and source records attributed to M Kwantes.
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A standardized methodology was used to study the in vitro behavior of different strains of Neisseria gonorrhoeae when treated with povidone-iodine. The bactericidal activity of the antiseptic was appraised using the dilution-neutralization technique on four gonococcal strains, two of which produced a beta-lactamase. Bactericidal activity in aqueous medium was observed down to a dilution of 1/128. This result specifies the conditions under which this antiseptic is active against Neisseria gonorrhoeae.
The MS-2 automate for antibiotic susceptibility testing was experimented under conditions different from those recommended by the manufacturer, namely using antibiotic discs from different firms. Susceptibility of eight Enterobacteriaceae strains recovered from urine to nine antibiotics borne by discs from three different firms was tested. Results obtained with the different brands of discs were dissonant in less than 7% of cases (major and minor disagreements compounded). Major discrepancies ranged from 2.8 to 4.2% according to the origin of discs. The reproducibility study found consistent results in 87.5% of cases, and satisfactory results (i.e. minor discrepancies excluded) in 93.5% of cases.
Atypical mycobacteria were isolated from 16 patients admitted to the Versailles Hospital Center over a two-years period (1981-1982). Two cases of pulmonary disease due to M. avium-intracellulare and one case of skin disease due to M. marinum were diagnosed. Pulmonary infection remained doubtful in two patients despite repeated recovery of M. Kansasii and M. chelonei.
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The authors report a case of meningitis, presenting all characteristics of the disease described in 1944 by P. Mollaret, occurring in a child aged 2 years and 8 months. They stress the rarity of cases on childhood. The cells found in the cerebrospinal fluid, photographs of which are included, are fragile and may undergo early lysis. They are present in association with lymphocytes and polynuclears, giving the slide examined a highly characteristic mottled appearance. The authors raise the question of the morphological similarity of these large cells, with their polygonal contour and small central nucleus, with an epithelium.
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The authors analyse 42 cases of bacteroides infection regrouping bacteremia and localised infection collected over a period of one year. The route of entry was almost always digestive. The prognosis seems mainly to depend on the background. The bacteriological diagnosis is now easy and germ-sensitivy is stereotyped.
Two cases of fulminating pneumococcal septicemia (FSP) are reported, and 47 confirmed cases were discovered after a review of the published literature. The syndrome is that of a malignant infection with fever, collapse, and disseminated intravascular coagulation, with a rapid mortal outcome in most cases. Etiologically, FSP is usually the consequence of functional or anatomical asplenia, and the relative frequency of this affection after splenectomy following trauma confirms this observation. Lack of a splenic filter and a deficiency in the phagocytic system are the reasons for microbial proliferation in the blood, and the lymphocytic defence mechanisms are inactive because of the absence of any focus of infection.