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Biomedical subjects

M Kun

Publications and source records attributed to M Kun.

At least 37 records · Page 2Linked to original sources

[Prevention of suture insufficiency using seromuscular gastric wall patch].

Seromuscular patches were prepared from the wall of the resected stomach of 20 dogs. The patches were used in the form of allogeneic and autologous grafts fixed with Histoacryl adhesive to cover gastric and intestinal sutures and gastric perforations. The aim was a hermetic closure of the wound and the prevention of suture insufficiency. In the 7 to 90 days follow-up period a perfect organization was observed in all the cases. On the basis of the favourable experimental results the clinical application of autologous seromuscular patches is suggested.

Animals↗

[Covering the resected surface of parenchymatous organs with histoacryl-N-blue tissue adhesive and a seromuscular patch from the gastric wall].

Seromuscular patches were prepared from the gastric wall of 20 experimental dogs and used in the form of autologous or allogenic transplants for the covering of the resection surface of parenchymal organs (liver, spleen, pancreas). The patches were fixed by means of the tissue adhesive Histoacryl-N-Blue; the aim was to achieve haemostasis and to prevent running of the secretion. In the 1 to 90 days follow-up period the patches completely organized and in none of the cases did haemorrhage occur. On the basis of the good experimental results the authors suggest the possibility of the clinical application of autologous patches.

Animals↗

Morphological changes in the CNS after Dimer X ventriculography.

The brains of 89 cats were investigated after the stereotactic injection of Dimer X into the ventricular system. The animals were sacrificed after 6, 24 and 48 h and after 7 and 30 days. Morphological changes were found in the ependyma, choroid plexuses, subependymal zone and in the brain tissue. They were most intense within 2 days of the experiment and some lesions (subependymal inflammatory infiltrates and ependymitis granularis) persisted up to 30 days. Similar changes were revealed postmortem in the brains of 20 patients in whom Dimer X ventriculography had been performed.

Animals↗

[Etiopathogenesis of mycotic aneurysms].

In a patient after operation for metastatic bronchogenic brain abscess presence of aneurysm was demonstrated during control carotid angiography. In previous angiography the aneurysm had not been seen. During further observation the size of the aneurysm decreased. The patient died 5 weeks after the operation due to rupture of lung abscess into the pleural cavity. Microscopic examination showed that the lesion was in fact pseudoaneurysm. The authors discuss the mechanism of development of mycotic aneurysms and their possible role in the pathogenensis of metastatic brain abscesses.

Adult↗