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Biomedical subjects

M Krbec

Publications and source records attributed to M Krbec.

23 records · Page 2Linked to original sources

[Locked nailing of fractures of the long bones. 1. Fractures of the leg].

The authors present an account of their initial experience with the use of a method of locked nailing of fractures of the leg, applying the technique described by Grosse and Kempf. They use original implants of Howmedica Co. They indicated for osteosynthesis closed fractures of the leg in the middle three fifths of the bone length, without major damage of soft tissues (grade 0 and 1 of Tscherne's classification). In injuries with imminent compartment syndrome they operated after a delay, in all others they operated early after injury. Using the described method, the authors operated 16 patients. In three instances they used static locking of the nail, in 13 instances dynamic locking. The authors did not observe any delayed healing of the fractures. The only complication was partial paresis of the deep branch of the peroneal nerve. In all instances the patients were allowed to weight-bearing of the operated extremity soon--on average 3.5 weeks after operation. Recovery followed after 8-15 weeks. The authors consider this method with regard to the possible functional treatment, stability for weight-bearing, and rapid recovery of the fracture as the optimal therapeutic procedure for almost all types of closed fractures in the middle three fifths of the leg.

Adolescent↗

[Changes in collagen biosynthesis in patients with hip joint replacement surgery and reoperation].

The authors investigated the intensity of collagen synthesis in patients subjected to operation or re-operation of a total endoprosthesis of the hip joint. The patients suffered from osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. The authors assessed the activity of collagen glucosyl transferase (S-GGT) and the concentration of the N-terminal propeptide procollagen type III by two methods (S-Pro III-N-P and S-Fab) in serum before and after operation. A significant rise of S-GGT and S-Fab, as compared with controls, occurred only after operation while S-Pro III-N-P was elevated already before operation. S-GGT did not differ before and after operation, while N-propeptide concentration rose when either method was used.

Adult↗