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Biomedical subjects

M Kowada

Publications and source records attributed to M Kowada.

At least 163 records · Page 9Linked to original sources

Association of arteriovenous malformation and intracranial aneurysm in the posterior fossa.

Two cases of a saccular aneurysm of the posterior inferior cerebellar artery associated with an anatomically related arteriovenous malformation are presented. The aneurysms were clipped and the arteriovenous malformations were totally extirpated in one-stage operations in both cases. The association of arteriovenous malformation and arterial aneurysm in the posterior fossa was reviewed in the literature.

Cerebellum↗

[Electron microscopic study of metastatic hemangiopericytic meningioma].

Electron microscopic observations in a case of metastatic hemangiopericytic meningioma was presented. Cell origin of this tumor was discussed in detail from the point of the leiomyoblastic differentiation. The patient was a 49-year-old woman who was operated four times in the past for the cerebellar tentorial and the left parasagittal tumors. Six years after the first operation, metastatic lesions were found in the rib, the liver, the cervical vertebra and the sternum. Specimens were prepared from the intracranial and the rib tumors. On light microscopy the tumor cells with large nuclei and scant cytoplasm were proliferated around an endothelial-lined capillaries constituting obstructive or distended lumens. Mitoses and focal necrosis also existed. On electron microscopy the tumor cells were ovoid or ellipsoidal and had large irregular-shaped nuclei with conspicuous nucleoli. Knob-ended cytoplasmic processes occupying among tumor cells formed interdigitation. Microorganellae such as rough endoplasmic reticulum, Golgi apparatus, and mitochondriae were well developed. Glycogen granules were abundant. Some cells had a large number of 5-7nm microfilaments. Occasionally these filaments condensed into the dense body-like structure parallel to the cell surface. Pinocytic vesicles were not observed. Vascular channels varied in shape. The capillaries were lined by an endothelial cell. The endothelium had pinocytic vesicles under the plasmalemma and intracytoplasmic processes projecting into the vascular lumen. The neoplasmic cells and capillaries were surrounded by the basement membrane-like substance which consisted of amorphous and fibrous components.(ABSTRACT TRUNCATED AT 250 WORDS)

Cerebellar Neoplasms↗

[Jugular foramen neurinoma--report of a case (author's transl)].

A case of jugular foramen neurinoma was presented in detail with a review of fifty-seven cases reported in the literature. A thirty-six-year old man was admitted to the hospital with complaints of tinnitus and hearing loss in the right side with vertigo. Neuro-otological examination revealed the definite sensorineural hearing loss and the disturbance of vestibular function on the right. Cranial nerve palsy was not revealed except for the right eighth nerve. Craniotomogram and axial view showed enlargement of the right jugular foramen. CT, vertebral angiogram and pneumoencephalotomogram demonstrated a space taking lesion at the right cerebellopontine angle. By suboccipital craniectomy a walnut-size tumor was disclosed at the jugular foramen with total removal. However, the origin of the tumor was not confirmed. The post-operative course was uneventful and hearing loss was gradually improved.

Adult↗

Computed tomography of Moyamoya disease: demonstration of occluded arteries and collateral vessels as important diagnostic signs.

Diagnosis of moyamoya disease primarily depends on the angiographic demonstration of stenosis and occlusion of the carotid bifurcation, and extensive parenchymal and leptomeningeal collaterals. According to previous reports, computed tomography (CT) reveals multiple low density areas in the brain, with atrophic changes. Based on this review of six cases, CT with contrast enhancement often reveals tortuous, curvilinear vessels in the basal ganglia, corresponding to extensive parenchymal and leptomeningeal collaterals on angiography. The most proximal portions of the anterior and middle cerebral arteries are often poorly visualized. When multiple low density areas or subarachnoid hemorrhages are encountered on CT, these findings in the basal ganglia should be sought for differential diagnosis.

Adult↗

[Spontaneously cured carotid-cavernous fistula verified by angiography--report of a case (author's transl)].

A case of spontaneously cured carotid-cavernous fistula has been reported in details with a review of literatures. Seven cases verified by angiography have been described so far in the literature. Spontaneous cure has been revealed within 6 months after the initial examination in 5 out of 7 cases by follow up angiography, and has occurred in five women of middle age. The presented case was a 45 year-old female who has suffered from the exophthalmos associated with disturbed eye movements of two months duration. On January 2, 1977, the carotid angiography demonstrated a c--c fistula and an oval aneurysm of the middle cerebral artery on the right side. The exopthalmos was slowly decreased with the conservative treatment after two months. The c--c fistula was not demonstrated by the angiography carried out on March 10, 1977, and was not revealed thereafter by follow up studies.

Arteriovenous Fistula↗

[An operated case of clivus chondroma (author's transl)].

A case of clivus chondroma was presented in detail with a review of twenty-four cases reported in Japan. A twenty-eight-year-old house wife was admitted to hospital with complaints of muscle weakness and numbness on the right side of the body. Neurological examination revealed the right hemiparesis and hemihypesthesia. Cranial nerve palsies were also disclosed on the right Vth and the left IXth, Xth and XIth nerves. Craniograms showed a ring-like calcified shadow localized in the clival region without definite bone destruction. Roentgenograms disclosed many well-demarcated radioluscent areas in the phalanges of both hands and feet. The marked separation between the basilar artery and the clivus was demonstrated on vertebal angiograms and pneumoventriculograms. CT scan showed an irregularly shaped low density area localized on the clivus, which turned out to be enhanced following contrast infusion. The tumor was partially removed by the subtemporal approach, and was histologically chondroma. The patient was discharged, gaining adequate muscle strength after operations.

Adult↗