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Biomedical subjects

M Kornitzer

Publications and source records attributed to M Kornitzer.

At least 91 records · Page 5Linked to original sources
PubMed1985

[Physical activity, physical fitness and coronary disease].

The relationship between physical activity on and off the job, physical fitness and coronary artery disease was investigated in a prospective study involving 2 363 men, 40 to 55 years old. Sudden death and myocardial infarction occurred in 31 subjects during a 5-year follow-up. Preliminary data are reported. There was no significant correlation between quartiles of physical activity on and off the job and incidence of coronary events. Physical fitness was significantly inversely correlated with incidence of coronary events (p less than 0.05) and was significantly lower in the 31 new cases (p less than 0.03). Multivariate analysis showed that HDL-cholesterol, smoking and physical fitness significantly and independently discriminate between coronary prone patients and healthy subjects. We conclude that physical fitness is an independent, inverse risk indicator of new coronary events.

Adult↗
PubMed1984

Blood pressure distribution and electrolytes excretion in a sample of the Nepalese population.

This paper presents the distribution of the blood pressure in a sample of 355 Nepalese citizens and the Na+ and K+ content in 180 morning urine spots. The blood pressure distribution suggests that this sample has the characteristics of a "low blood pressure population". The Na+/K+ ratio in the urine spots is relatively high (mean +/- S.D.: 4.6 +/- 3.4). Hypotheses concerning these contradictory findings are proposed.

Adult↗
PubMed1983

Belgian heart disease prevention project: incidence and mortality results.

Results are presented from the Belgian Heart Disease Prevention Project, part of the WHO European Collaborative Trial in the Multifactorial Prevention of Coronary Heart Disease (CHD). 19 409 men aged 40-59 yr took part; they were employed in thirty factories which formed the allocation units for a randomised controlled trial lasting 5-6 yr. The intervention package consisted largely of health education promoting a cholesterol-lowering diet, smoking cessation, weight control, physical activity, and treatment of arterial hypertension. A programme of information was supplemented by face-to-face counselling at the workplace by two physicians attached to the project. The coronary risk profile was reduced in the intervention group, compared with that in the control group, especially during the first 4 yr, by effects on serum cholesterol, number of cigarettes smoked daily, and arterial blood-pressure. Total mortality was 17.5% lower in the intervention group than in the control group (p = 0.038). Coronary mortality was reduced by a non-significant 20.8% whereas CHD incidence (non-fatal myocardial infarction plus fatal myocardial infarction plus sudden deaths) was reduced by 24.5% (p = 0.031). Non-fatal myocardial infarction (not a major end-point) was similarly reduced by 26.1% (p = 0.030).

Adult↗
PubMed1983

Behavior, stress, and psychosocial traits as risk factors.

Although psychosocial factors have long been associated with the pathogenesis of heart disease, the independent relation between these variables and coronary heart disease (CHD) is still controversial. However, when experimental, clinical pathological, and epidemiologic studies are taken together, strong evidence is provided that psychosocial and behavioral factors are important in the development and the provocation of clinical CHD manifestations. Heterogeneity in study results is partially due to methodological problems in defining and measuring behavior, stress, and psychosocial traits in population groups as well as in individuals. The difficulties in separating the role of psychosocial factors from the classic risk factors strengthen the importance and need for these factors to be considered in the design of further clinical and epidemiologic studies, not only to explore their independent predictive value but also to study their role in adherence to preventive advice and in the reversibility of risk. In these respects results are presented from a prospective epidemiologic and from a controlled multifactorial intervention study.

Adult↗
PubMed1983

Prevalence of left ventricular hypertrophy in middle-aged men according to various ECG-VCG techniques.

The prevalence rates of left ventricular hypertrophy (LVH) were studied in a middle-aged male working population using the Minnesota code, an automated processing of the orthogonal leads, and the Pipberger program. These various methods resulted in significant differences in prevalence rates. The odds ratios and relative differences were calculated for each method in subgroups according to the presence or absence of personal antecedents of arterial hypertension. For detecting LVH, the orthogonal criteria are superior to the other methods. The concordances between methods are low overall, leaving the question open as to the independent prognostic value of each method.

Adult↗
PubMed1983

Type A in relation to job-stress, social and bioclinical variables: the Belgian Physical Fitness Study.

The present study focuses on the relationship of Type A behavior, a suspected coronary-prone behavior pattern in its overall or specific aspects, to "stress" experienced at work, and to social and coronary bioclinical risk factors. In order to measure Type A behavior and Job-Stress, respectively, the Jenkins Activity Survey Questionnaire (J.A.S. for employed persons, 1969 version) and a self-constructed Job-Stress Questionnaire were administered at a base-line examination to 2,302 men aged 40-50 years. The multivariate analysis shows: A strong Type A behavior-Job-Stress relationship; An important relationship between employment grade, educational attainment and--to a lesser extent--, marital status and, overall Type A behavior, Speed and Impatience and Job-Involvement, A weak relationship between cholesterol and triglycerides (not found in univariate analysis), and, overall Type A behavior; a small weak relationship between smoking habits, and, Speed and Impatience and Hard-Driving. A direct relationship between heavy physical activity during leisure-time and Job-Involvement.

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PubMed1983

Belgian heart disease prevention project: comparison of self-reported smoking behaviour with serum thiocyanate concentrations.

At the end of a multifactorial cardiovascular preventive trial serum thiocyanate was measured in random samples of 1035 cases and 1087 controls. A cut-off point 0.45 mg/dl (77.6/mumol/l) gave a sensitivity of 82.1% among the cigarette smokers in the control group and a specificity of 91.0% among the non-smokers. When the intervention and control groups are compared in terms of self-reported smoking behaviour non-significant differences in mean thiocyanate concentration are observed for those who never smoked, ex-cigarette smokers, actual cigarette smokers, and in four different cigarette smoking categories. Our results fail to confirm the reported pessimistic views concerning the validity of self-reported smoking behaviour in subjects taking part in intervention trials.

Adult↗
PubMed1982

Metrological study of psychological questionnaires with reference to social variables: the Belgian Heart Disease Prevention Project (BHDPP).

In the framework of a controlled trial on the multifactorial prevention of coronary heart disease, two measures of type A behavior--determined by the Bortner scale and the Jenkins Activity Survey (JAS)--and one personality questionnaire--the Sandler Hazary Questionnaire and Eysenck Personality Inventory (SHEPI)--were used. Their interrelations and relations with social variables are analyzed. It appears that the Bortner scale and the JAS do not measure the overall syndrome of the coronary-prone behavior pattern (CPBP), but similar and different specific aspects of it. There exists a direct relation of the Bortner score, JAS-AB, JAS'-S, and JAS-J with the study level and the socioprofessional class. Neuroticism or emotional hyperreactivity determined by the SHEPI is highly correlated with these scores. No or small relations of social variables with personality traits are found.

Adult↗
PubMed1981

The Belgian Heart Disease Prevention Project: type "A" behavior pattern and the prevalence of coronary heart disease.

A relation between the Type A behavior pattern and the prevalence of coronary heart disease (CHD), independent of other coronary risk factors, was demonstrated in the Belgian Heart Disease Prevention Project. The association was strongest with angina pectoris or with electrocardiogram (ECG) abnormalities in subjects with known CHD; however, particular aspects of the Type A behavior pattern dealing with time urgency were also related to ECG abnormalities in patients with no angina pectoris and no history of CHD.

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