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Biomedical subjects

M Koenigsberg

Publications and source records attributed to M Koenigsberg.

At least 55 records · Page 3Linked to original sources
PubMed1986

Uterine artery Doppler velocimetry in pregnant women with hypertension.

Uterine and umbilical artery velocimetry was carried out on 71 women with hypertensive disorders in pregnancy. Three categories of hypertensive disease were diagnosed: chronic hypertension, preeclampsia, and chronic hypertension with superimposed preeclampsia. Clinical classifications describe the severity of disease effectively, primarily because the classification is based on the appearance of abnormal physical or laboratory findings. Doppler velocimetry of the uterine arteries shows that normal pregnancy occurs when the systolic/diastolic ratio is less than or equal to 2.6. When the ratio exceeds this level and there is a notch in the waveform, the pregnancy is complicated by stillbirth, premature birth, intrauterine growth retardation, and maternal preeclampsia. The positive and negative predictive value of the examination is 93% and 91%, respectively. It appears that this new technology will be an essential ingredient of optimum pregnancy surveillance.

Adult↗
PubMed1986

Infantile seizures caused by voluntary water intoxication.

A case of infantile seizures of unusual etiology and presentation is described. Water intoxication with resultant epilepticus was caused by ingestion of nearly 150 ml/kg of fresh water on the day of presentation. It is unclear why the infant voluntarily consumed so much water, but heat illness is the most probable cause.

Diagnosis, Differential↗
PubMed1984

Sonography and computed tomography in the diagnosis of carcinoma of the gallbladder.

The computed tomographic and sonographic findings of 26 patients with gallbladder carcinoma were reviewed, and the problems and pitfalls encountered with these imaging techniques are discussed. The most common finding, a mass filling or replacing the gallbladder, was seen in 42% of the patients. A mass protruding into the gallbladder was seen in 23%, and diffuse asymmetric thickening of the gallbladder wall in 15%. Recommendations are made to avoid some of the diagnostic problems encountered. With careful and meticulous technique early carcinoma of the gallbladder may be detected with greater frequency by cross-sectional imaging techniques.

Aged↗
PubMed1983

The value of ultrasound in the diagnosis of popliteal artery aneurysms.

Although popliteal artery aneurysms are among the most common type of peripheral artery aneurysm, they may be difficult to diagnose until complications such as peripheral embolization, acute thrombosis and rupture occur. Pressure on adjacent structures may cause neurological symptoms and venous thrombosis. The diagnosis of peripheral artery aneurysms is usually made by physical examination and arteriography. Recently, ultrasound of the popliteal space has been found to be very useful in the diagnosis of popliteal artery aneurysms. It is therefore important to recognize the value of ultrasound for imaging popliteal artery aneurysms and to use this readily available non-invasive modality in patients in which physical examination and/or angiography of the popliteal fossa is equivocal. We present one case of a popliteal artery aneurysm which was missed by angiography and physical examination in which ultrasound was very important in diagnosing this aneurysm pre-operatively, and two cases in which the ultrasound examination confirmed the presence of the popliteal artery aneurysm but better delineated its size than did angiography.

Aged↗
PubMed1982

Gray-scale ultrasonic demonstration of peripancreatic adenopathy.

The ultrasonic appearance of peripancreatic adenopathy in ten patients is described. The enlarged nodes may appear as well-defined, echo-poor, ovoid or rounded masses in a retropancreatic location, or they may surround and silhouette the region of the pancreatic head and body. The former appearance should be easy to differentiate from primary pancreatic neoplasm, but with a confluent mass of peripancreatic nodes it may be impossible to exclude pancreatic disease.

Adult↗
PubMed1981

Morphological changes in the surface characteristics of cultured cells after exposure to diagnostic ultrasound.

Morphological changes in the surface membranes of cultured Balb/c 3T3, clone 1-13 cells were studied by scanning electron microscopy after the cells were exposed to diagnostic ultrasound. Abundant irregular, dense microvilli appeared in transformed clones as well as in cells that had been exposed to ultrasound, but had not been morphologically transformed. This increased density of microvilli was detected as early as three days after ultrasound and was still present 37 days later. In comparison, unexposed control cells were smooth with occasional microvilli. Further studies are needed of the effects of diagnostic ultrasound.

Animals↗
PubMed1981

Mechanisms of mitral valve motion during diastole.

To examine the mechanisms of mitral valve motion in mid diastole and at closure, we simultaneously measured mitral flow (electromagnetic), valve motion (echo), and atrioventricular pressures (micromanometer). Peak valve excursion (E point) occurs early 46 +/- 7 ms) after opening and always precedes peak flow; therefore, mid-diastolic closing motion (EF slope) is not due to flow deceleration or vortex formation. Large variations in peak flow are accompanied by small variations in valve excursion (coefficient of variation 41 vs. 12%, respectively). We conclude that the valve overshoots its equilibrium position and that the chordae produce tension on the valve during diastole. This approach is supported by data from papillary muscle rupture, prolonged P-R interval, and mathematical modeling. We offer a valve-closure theory unifying chordal tension, flow deceleration, and vortices, with chordal tension as a necessary condition for the proper function of the other two. Nevertheless, prolonged periods of diastasis and ventricular premature contractions indicate that competent valve closure may occur in the absence of vortices and flow deceleration.

Animals↗
PubMed1979

Examining the anterior right kidney. Frequent lack of appreciation in examination of the right upper quadrant.

An anteriorly positioned lower pole of the right kidney is often unappreciated on physical examination. Yet, on review of a large number of abdominal sonograms, more than 12% of the patients had a right kidney with a lower pole sufficiently anterior in position so as to lie at the same depth as the anterior surface of the liver. In a group of patients referred for ultrasound evaluation of hepatomegaly, 20% proved to have a normal liver and an anteriorly positioned lower pole of the right kidney.

Abdominal Neoplasms↗