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Biomedical subjects

M Knoll

Publications and source records attributed to M Knoll.

At least 55 records · Page 3Linked to original sources

Doppler echocardiographic assessment of left ventricular systolic and diastolic function in mild hypertension.

Abnormalities in left ventricular (LV) wall thickness and mass have been demonstrated in patients with mild hypertension utilizing M-mode echocardiography. In addition, studies using radionuclide angiography have demonstrated abnormalities in early diastolic LV filling in asymptomatic hypertensive patients with normal ejection fraction and cardiac output. Recently, Doppler recordings of flow velocity in the ascending aorta and through the mitral valve have been shown to provide useful information about LV function. To determine whether flow abnormalities could be detected in patients with mild hypertension, we recorded Doppler aortic and mitral valve flow velocities in 21 men with mild hypertension. Casual systolic blood pressure was 147 +/- 18 mm Hg (mean +/- SD) and diastolic blood pressure was 96 +/- 9 mm Hg. LV mass (310 +/- 75 g) was elevated (i.e., above the 95% normal prediction interval) in 8 of 19 patients who underwent M-mode echocardiography; LV ejection fraction was normal in all patients (mean, 80%). As in previous studies in normal subjects, we found in these hypertensive patients an inverse correlation between age and both aortic peak flow velocity (r = -0.51, p less than 0.05) and transmitral early diastolic peak flow velocity (r = -0.44, p less than 0.05) and a positive relationship between age and mitral valve late diastolic peak flow velocity (r = 0.73, p less than 0.001).(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

[The body as the site of self and other perception--a contribution to the identity problem].

The author differentiates between two modes of perception, one is the "expressive" mode, stabilizing and aiming at constancy, the other is the "impressive" mode, penetrating the self and aiming at identification with the percept. The clinical relevance of the latter for the therapy of psychoses is demonstrated by five case studies. The "Leib" as the place of incidence of perception is viewed in its function for the interaction of physician and patient: above all psychotic border states induce forms of communication, which are remarkably close to the body and remain mostly unconscious, but might be the beginning and instigation of a whole of behaviour-(action) chains on the side of the therapist. For the purpose of a controlled handling of the instrument of therapeutic intervention it is necessary to bring to view precisely these processes occurring close to the body. The traditional idea of identity is embarrassing this process of perception.

Adult↗

Dependence of urine composition on the age and sex of healthy subjects.

The lithogenic and inhibitory substances in the 24-h urine of 150 healthy females and 150 healthy males were recorded. These two groups were further subdivided into 6 different age-groups, with 25 in each group. The 24-h excretion in these various age-groups displayed considerable differences in some cases, particularly in the case of the pH value, and the Ca, Mg, citrate and phosphate excretion of the women, and the Ca, Mg, uric acid, Na and K excretion of the men. All the parameters measured with respect to the males displayed higher levels of excretion than those of the females.

Adolescent↗

Effect of imaging view and sample volume location on evaluation of mitral flow velocity by pulsed Doppler echocardiography.

Pulsed Doppler mitral flow velocity measurements have been used to evaluate left ventricular diastolic filling. In normal persons these measurements are affected by age and respiration, but not by gender, body surface area or normal blood pressure. Additional factors that may influence these measurements include the imaging view and sample volume location. In this study, the effects of imaging view and sample volume location were evaluated in 52 normal subjects, aged 21 to 78 years. Pulsed Doppler recordings were obtained from the apical 4-chamber and apical 2-chamber views with the sample volume located both in the left atrium and at the level of the mitral valve leaflet tips. Doppler measurements were slightly, but not significantly, higher (4% on average) for recordings obtained from the apical 4-chamber than from the 2-chamber view for peak flow velocity in both early and late diastole. However, apical 4-chamber recordings from a sample volume in the left atrium resulted in measurements significantly lower (p less than 0.05) for both early and late diastolic mitral peak flow velocity than those obtained near the mitral leaflet tips (peak flow velocity in early diastole = 43 +/- 12 vs 57 +/- 12 cm/s and peak flow velocity in late diastole = 36 +/- 7 vs 46 +/- 11 cm/s, respectively). The higher mitral peak flow velocity values recorded in early and late diastole near the mitral leaflet tips may be related to the smaller flow area at the mitral valve orifice compared with the left atrium.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Shear strength of brackets bonded to anterior and posterior teeth.

A study was undertaken to determine the maximum shear strength of brackets bonded to anterior and posterior teeth. Brackets were bonded to two groups comprising 12 incisor and 12 molar teeth. After storage in water at 37 degrees C for 10 days, each bracket was tested to failure in a shear mode in a Instron machine. The mean value for the incisors was 164.3 +/- 35.1 kg/cm2 (16.1 +/- 3.4 MPa) and 115.7 +/- 41.1 kg/cm2 (11 +/- 4.0 MPa) for molars. These values, analyzed in a two-tailed test, were statistically different at the 0.01 level of confidence. It was concluded that differences in etching patterns do not necessarily affect shear bond strength and that the predominantly weak link in the bonding chain was at the bracket/resin interface. The lower values for molar teeth may relate to adaptation of the bracket and nonuniform resin thickness.

Acid Etching, Dental↗

[Ecology of depression and sexuality in the climacteric and involution in the female].

The evaluation of psychiatric histories of 56 women from the age of 45 to 60 diagnosed as monopolar depressions demonstrates the incongruence of natural-scientific and interpreting (hermeneutic) competence. In 60% of the cases no details about the gynecological anamnesis could be found; in 36% informations about the sexual selfperception by the patients were available; these informations were not placed under a specific category of anamnesis but scattered throughout the text and left a exigency of interpretation. Gynecological pains in a wider sense appeared in half of the cases. These datas are put in the frame of a specific, socially preformed idea of female aging, which indeed gives place to the here studied depressive syndrome, but not to a suitable mode of expression according to age, sexual desire resp. female individuality. The term of "ideal motherliness", i.e. a motherliness without the obligation to produce children, is introduced here as a possible therapeutic and social criticism. The interdependence of sexual mode of expression on one side, which is granted or not granted from a certain age on, of psychiatric symptoms becoming relevant and a fitting niche on the other is called 'ecology' with regard to the said background and according to Bateson. So the dysfunctional stabilization of the patient is regarded as a reflexive kind of way.

Adaptation, Psychological↗

[The origin of violence in psychiatry--a contribution to double-bind rage].

The discussion about Euthanasia newly has raised the question on the violent implications of interaction in psychiatry. Psychiatry is under obligation of the forces of order on one, of the wish to help on the other side. This double bind reflects an interactional feature of construction which the psychotic patient has to go through, but which he carries on too. The selfreduplicative construction of originally individual double bind-situations corresponds to the patient's conception of live, but evokes a specific, only perceptible at short notice, disintigrating "double-bind-Wut" in the involved therapist, which mainly is endangering the patient. The state of "double-bind-Wut" and the working up of this rage is determined by the primary process therefore directly unconscious. We investigate to what extent the "double-bind-Wut" is to make perceptible and thus to handle; by the means of casuistic microstructures we give reasons for the assumption that the desintrating power of "double-bind-Wut" might become a methodical paradigm of future research.

Anger↗

Innominate artery aneurysm with thrombus: detection by two-dimensional echocardiography.

A 51 year old man with an innominate artery aneurysm presented with claudication and ischemia of the right forearm and hand. Two-dimensional echocardiography visualized the saccular aneurysm and a pedunculated mobile thrombus within it that were not seen during aortic arch angiography. Two-dimensional echocardiography, shown to be useful in identifying intracardiac masses and aortic aneurysms, may be important in selecting patients with increased risk of embolization.

Aneurysm↗

[Psychiatric concept of health--its dialectic and reflective determination].

The subjectivity of the subject of psychiatry calls for a specific method, which cannot be developed in analogy to objectifying methodologies. Taking the current discussion of normative methods as an example, it is suggested to integrate the method of Hegel's logic into psychiatric thinking. In the following study, this suggestion is explained with reference to the problem of the scientific approach and to the dialectical constitution of illness and health.

Female↗