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Biomedical subjects

M Kloss

Publications and source records attributed to M Kloss.

28 records · Page 2Linked to original sources

The management of severe preeclampsia with intravenous magnesium sulphate, hydralazine and central venous catheterization.

A prospective study of patients with severe preeclampsia managed by magnesium sulphate infusion for eclampsia prophylaxis, hydralazine infusion for vasodilatation and central venous catheterization for fluid monitoring is reported. In this preliminary report of 46 patients, there was no episode of eclampsia following treatment, no maternal death, and hypertension was well controlled in all patients. Of the 51 babies born, there were 7 stillbirths, and 4 neonatal deaths; 6 of the 7 stillbirths were less than 30 weeks' gestation, and 23 of the 46 patients were delivered by Caesarean section.

Acute Disease↗

Family births at the Royal Women's Hospital, Melbourne.

A controlled study comparing clinical aspects of birthing unit confinement with orthodox obstetric care in a major obstetric hospital is detailed. The results confirm that this centre provides an acceptable and safe alternative for those who desire such an environment.

Delivery, Obstetric↗

Multiple dose extraamniotic prostaglandin gel for second trimester termination of pregnancy.

Multiple doses of PGF2 alpha gel were administered into the extraamniotic space in 30 patients to induce mid-trimester termination of pregnancy. In 18 of these patients, repeat doses of gel were given only in the absence of uterine contractions and in 12 patients the gel was administered every 4 hours, irrespective of uterine activity. The mean time to abortion in all patients was 13.9 hours; no benefit seemed to accrue from using routine 4-hourly doses and it is recommended that repeat doses are given only when contractions are absent. The latter technique compares favourably with the use of other natural prostaglandins and prostaglandin analogues.

Abortifacient Agents↗

Single dose extra-amniotic prostaglandin gel for midtrimester termination of pregnancy.

The efficacy of a single dose of prostaglandin F2 alpha gel instilled into the extra-amniotic space to induce termination of pregnancy in the second trimester has been assessed and compared with intra-amniotic prostaglandin F2 alpha and with an extra-amniotic infusion of prostaglandin F2 alpha combined with intravenous oxytocin. There was no significant difference between the methods in time taken to abortion, incidence of retained placenta, need for blood transfusion, or rate of sepsis. Single dose extra-amniotic prostaglandin gel is recommended as a safe, effective, and convenient method of midtrimester termination of pregnancy.

Abortion, Induced↗