[Involvement of the pineal gland in regulation of neoplasm growth].
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Biomedical subjects
M Klencki
Publications and source records attributed to M Klencki.
Size of thyrocyte nuclei in aspirates from follicular adenomas: correlation with patients' ages.
OBJECTIVE: To determine whether the size of thyrocyte nuclei in aspirates from follicular adenoma correlates with the age of patients. STUDY DESIGN: The karyometric parameters were evaluated in routine aspirates, obtained from 27 patients with follicular adenoma as diagnosed in postoperative histopathologic examinations. The ages of the patients ranged from 11 to 70 years (36.8 +/- 16.3, x +/- SD). The cytologic examination of all the aspirates before surgery revealed "follicular neoplasms." The karyometric evaluation was performed with Karyometry Manager, version 1.2, an image analysis computer system. RESULTS: Neither the mean nuclear volume, mean nuclear intersection area nor mean nuclear perimeter correlated with the ages of the patients. CONCLUSION: These results suggest that in contrast to nodular goiter, in the cytologic examination of follicular neoplasms, the ages of patients should be disregarded when interpreting the size of thyrocyte nuclei.
Adenoma↗
Age-related changes in the size of thyrocyte nuclei in aspirates from nontoxic nodular goiter.
It is believed that the size of thyrocyte nuclei correlates with the age of the patient in both normal thyroid tissue and nodular goiter. Therefore, we examined karyometric parameters in aspirates obtained from 38 patients ranging from 18 to 79 years (48.8 +/- 15.2, mean +/- SD). Routine cytologic evaluation revealed nodular goiters in all the patients. Subsequently, the same smears were analyzed with a computer system for karyometric measurements. The mean volume, intersection area and perimeter of nuclei of thyrocytes from nodular goiters correlated positively with age. The results suggest that the age of the patient should be considered when interpreting thyrocyte nuclear size during cytologic examination.
Adult↗