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Biomedical subjects

M Kitano

Publications and source records attributed to M Kitano.

At least 181 records · Page 10Linked to original sources

[A clinical study on bilateral metachronous pneumothorax].

Three hundred and thirty-six cases of spontaneous pneumothorax were treated in our hospital from 1976 to 1988. In these 336 cases, there were 49 cases (14.6%) of bilateral metachronous pneumothorax. Bilateral metachronous pneumothorax happened significantly more frequently in the younger generation. There was no correlation between occurrence rate of contralateral pneumothorax and Brinkman index. In addition, postoperative contralateral recurrence occurred in 18.1% of surgical cases under general anesthesia. Especially nitrous oxide might have influence on postoperative contralateral recurrence.

Adolescent↗

[Successful treatment by using a pedicled omental flap for mediastinal infection in the presence of a external valved conduit].

Mediastinal infection is one of serve and fatal complications after cardiac surgery, especially in the presence of an artificial graft. A case of successful treatment by using a pedicled omental flap for mediastinal infection in the presence of an external valved conduit is reported. a 10-year-old girl who had implanted the 12 mm porcine valved conduit for truncus arteriosus at age 9 months, underwent replacement of the old conduit with a 18 mm valved conduit. On the 9th postoperative day, as soon as mediastinal infection was proved by positive culture of the drainage from the chest tube, a reoperation was performed to debride and irrigate the mediastinum. Irrigation with povidone-iodine and antibiotics was continued for 3 weeks until improvement of CRP levels and negative drainage cultures. Then the heart and the valved conduit were wrapped with the pedicled omental flap and the skin was closed. She was without any evidence of infection for 3 months after operation. Use of a pedicled omental flap might be an effective method for treatment of mediastinal infection in the presence of an external conduit.

Blood Vessel Prosthesis↗

[Delayed midsternal wound reconstruction for infants without secondary sternal closure].

Three infants, aged 11 days, 19 days and 48 days, underwent two Jatene operations and one modified Norwood operation. The sternum was left open and the skin defect was covered with a silicon sheet in all three patients. Delayed sternal closure was impossible because of hemodynamic deterioration in all three patients. Consequently delayed midsternal wound reconstruction was applied. One rectus abdominis muscle flap was turned up and the defect between the split sternum was filled with this muscle flap. Bilateral axillary incision was made to decrease the skin tension and the midsternal wound was closed with cutaneous advancement flaps. Bilateral axillary defects were covered with mesh skin implantation. All three patients recovered after this procedure. We propose this technique for the cases in which the delayed sternal closure is impossible.

Abdominal Muscles↗

Heterotopic central neural tissue of the tongue.

A rare case is reported of a pedunculated tumor containing heterotopic central neural tissue in the tongue of a 3-month-old girl. The lesion was located near the foramen caecum and was composed of glial cells, ependymal cells, a small number of neuronal cells and a relatively thick peripheral nerve.

Cell Nucleus↗

New bioabsorbable pledgets and non-woven fabrics made from polyglycolide (PGA) for pulmonary surgery: clinical experience.

A new type of bioabsorbable pledget made from non-woven fabric of polyglycolide (PGA) fibers has been developed. After the in vivo implantation test using dogs, samples were subject to clinical evaluations in pulmonary operations in four hospitals. The total number of trial cases was 50; in 11 cases pledgets were used for repair of the bronchus and in 39 cases for lung fistulas or defects of the pleurae. Compared with the conventional nonabsorbable pledgets, these PGA pledgets showed satisfactory results. In particular, for cases of emphysematous pulmonary diseases the application of the PGA pledgets and non-woven fabrics made the post-operative air-leakage duration short. In all these 50 cases neither side effect nor complication was observed. This evaluation suggests that PGA pledgets and non-woven fabric are an acceptable and even better alternative to conventional nonabsorbable pledgets for the pulmonary surgery.

Adolescent↗

Eosinophilic granuloma showing rapid regression. Report of a mandibular case with application of a modified PNA staining method for demonstration of Langerhans-type histiocytes.

A mandibular eosinophilic granuloma in a 16-year-old male is reported. This case showed rapid regression, which was clearly demonstrated by histopathological examinations of both preoperative biopsy and surgical materials. Transformation from an eosinophilic granuloma to a xanthomatous granuloma with multinucleated giant cells was observed after only 26 days. Special staining of paraffin sections with peanut agglutinin (PNA) and use of electron microscopy showed that the main component of the lesion in the biopsy material was Langerhans-type histiocytes. These cells had disappeared from the lesion by the time of the operation. At the same time, the number of infiltrating eosinophils was also markedly reduced. It seems appropriate to consider that the rapid regression of this disease was correlated with the rapid reduction in the number of Langerhans-type histiocytes appearing in the granulomatous foci, as well as the number of infiltrating eosinophils.

Adolescent↗

[Nucleolus organizer regions (NORs) in metastasizing pleomorphic adenoma].

The metastasizing pleomorphic adenoma of the salivary glands is a rare variant of pleomorphic adenoma with a benign microscopical appearance, but malignant biological behaviour and production of metastasis. The histopathological study with the routine techniques is not enough for disclosing the nature of these tumors and they are most of the times underdiagnosed as benign. The correct diagnosis, almost always too late, is evident after several recurrences and the detection of metastatic foci. The number of nucleolar organizing regions (NORs) detected with the silver colloid method can be used in histopathology to determine the degree of cell activity. We report the findings in a case of metastasizing pleomorphic adenoma of the submandibular gland. This technique demonstrated to be useful for the diagnosis and characterization of the metabolism of these tumors.

Adenoma, Pleomorphic↗

[Right ventricular outflow tract reconstruction in two neonates with pulmonary atresia and intact ventricular septum].

Two neonates, aged 8 and 18 days, with pulmonary atresia and intact ventricular septum underwent right ventricular outflow tract reconstruction with an autologous pericardial transannular patch. Preoperative cardiac catheterization revealed a tripartite right ventricular morphology with suprasystemic right ventricular morphology with suprasystemic right ventricular systolic pressure (right ventricular to left ventricular peak pressure ratio was 1.2 in case 1 and 2.0 in case 2). Right ventricular volume was 73.5% of normal and 115% of normal respectively. Generous resection of the infundibular myocardium was done and a patch was inserted with the heart kept beating as the perfusate temperature of 32 degrees C. In case 1 a modified Blalock-Taussig shunt was added on the postoperative day 21, because of the insufficient growth of the right ventricle, but in case 2 prostaglandin E1 could be discontinued on the postoperative day 9.

Female↗

[Clinical experience of adjustable pulmonary artery banding].

Pulmonary artery banding has been a useful palliative procedure for infants with congenital cardiac anomalies associated with excessive pulmonary blood flow. We have experienced some cases that the band was not sufficient enough to reduce the pulmonary artery pressure in complex cardiac anomalies. Therefore, we developed a new adjustable pulmonary artery banding system which can be re-adjusted extrathoracically without reoperation. We used this system in seven infants with congenital cardiac lesions and obtained good results.

Heart Defects, Congenital↗

[Eight cases of thymic cyst].

Eight cases of thymic cyst were treated in our hospital from Jan. 1967 to Oct. 1989, which were 5.6% of all mediastinal tumors and 35% of congenital cysts. All cases were discovered incidentally by routine chest roentgenograms. All but one had no respiratory symptoms. There were no associated autoimmunological disorders such as myasthenia gravis. These tumors showed water density in computed tomography, low intensity area in T1 and high intensity area in T2 weighted magnetic resonance image. Garium scans were negative in all cases. Operations were performed in all cases for their diagnosis and treatment. All of our cases had no signs of malignancy on pathological examinations, and they are free of recurrence during subsequent follow ups. Study of intracystic fluid revealed high titer of CA19-9 and CEA in spite of normal titer in serum, which might be useful clue to preoperative diagnosis. For the poor risk patients with thymic cyst, percutaneous aspiration might be diagnostic and therapeutic when there is no sign of malignancy.

Adult↗

[A case of successful closure of multiple lung fistulae by omental pedicle flap after intrapleural sponge plombage 34 years before].

A case of successful closure of pulmonary fistulae by omental pedicle flap is reported. A 58-year-old female with chronic empyema as a sequela of pulmonary tuberculosis was referred with complaints of fever and purulent sputa. After extirpation of spongy "Plombs" (Vinylsponge) which had filled pleural space in previous operation done 34 years before, omental pedicle flap was fixed by sutures to multiple lung fistulae. Omental pedicle was not filled up all the empyema cavity. We anticipate that an omental pedicle flap covering the lung fistulae will be a simpler but promising method of closing lung fistulae, while simultaneously preventive of infection of residual cavity.

Chronic Disease↗

[Multiple malignant schwannoma treated with a multidisciplinary therapy--a case report].

A 32-year-old man, complaining of an abdominal mass, was admitted to hospital where, on undergoing examination, the mass, which had spread widely through the abdominal cavity and the retroperitoneal space, was diagnosed as a malignant schwannoma with a liver metastasis. Thus, a multidisciplinary treatment was initiated and a remission was achieved. Later, however, he developed a multiple, local recurrence and died forty months after onset of his clinical symptoms. Since the prognosis of patients with a malignant schwannoma that do not undergo radical surgery is extremely poor, the authors emphasize the necessity of research for an effective adjuvant therapy.

Adult↗

Chondroma and osteochondroma of the tongue.

The first case of two separate tumors of the tongue, one cartilaginous and the other osteocartilaginous, is reported. The cartilaginous matrix of these two tumors contained elastic fibers and type II collagen. The histogenesis of these tumors is discussed.

Adult↗

[The use of omental pedicle flap for treatment in the field of thoracic surgery].

We present a series of 16 consecutive patients who underwent the omental pedicle flap method in the field of thoracic surgery. Fourteen of 16 patients were chronic empyema with bronchopleural fistulae and/or thoracic fistulae. A pedicle of omentum containing the right gastroepiploic artery was passed through a tunnel in the anterior diaphragm into the empyema cavity. It was fixed by mono-filament sutures on the bronchopleural fistulae. All but two patients were cured successfully by single-stage procedures. We also used a omental pedicle flap for mediastinal infection and reconstruction of the chest wall. We conclude that the use of omental pedicle flap is a promising method for treatment of serious infection in the field of thoracic surgery.

Adult↗

[A study on clinical findings and surgical treatment of pulmonary mycosis].

Between 1974 and 1987, 14 patients (10 male and 4 female) underwent thoracotomy for treatment of pulmonary mycosis. They were studied on their clinical findings and surgical treatment. The median age was 48 years (range 19 to 71 years). Fourteen cases consisted of 9 aspergillosis and 5 cryptococcosis. None of them was either debilitated or immunosuppressed before falling ill. Five of the 14 patients had other pulmonary disease and 11 had symptoms; i.e. hemoptysis or bloody sputum in 4 cases, chest pain in 3, fever in 3, cough and sputum in 2. Nine aspergillosis consisted of 4 aspergilloma, 3 aspergillus pneumonia and 2 aspergillus empyema. Three cases of aspergillosis occurred in preexisting cavity. Five cryptococcosis consisted of 3 pseudotumorous, 1 disseminated small nodular, and 1 infiltrative types. Preoperative diagnosis was as follows; pulmonary mycosis 5, pulmonary tuberculosis 4, lung cancer 3, empyema 1 and hydropneumothorax 1. Four patients underwent partial resection, 8 lobectomy, 1 pneumonectomy, 1 muscle prombage and thoracoplasty. The prognosis is satisfactory. All patients are alive and has no recurrence. On histopathological examination, in aspergilloma cases, invasion of aspergillus to surrounding lung tissue was not seen. In addition to well-known fact that blood-borne dissemination hardly occurred in aspergilloma in contrast to cryptococcosis. These findings suggest that aspergilloma and solitary lesion of cryptococcosis should be resected, and adjuvant chemotherapy should be accompanied for cryptococcosis.

Adult↗