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Biomedical subjects

M Kirsch

Publications and source records attributed to M Kirsch.

At least 181 records · Page 10Linked to original sources

Unit recordings from a new auditory area in the frontal neostriatum of the awake starling (Sturnus vulgaris).

Auditory units were recorded from a restricted region of the frontal neostriatum of the awake starling. This area (Field GA) was located latero-dorsal from the nucleus basalis and more closely associated with the caudal regions of the thalamo-frontal tract. Most units (46%) showed on-excitation to pure tones and white noise stimuli. No well-defined sustained firing was seen, but 15% of the units showed a weak type of excitation which outlasted the stimulus (long-lasting response). Tuning curves were broad. Unit response ranges extended from 150 Hz to 7.0 kHz (at 70--80 dB SPL). Habituation to repeated stimuli was obvious and also lability of response pattern; 26% of auditory units would not be reliably classified using pure tones or white noise. It is suggested that the response properties of Field GA units are typical of sensory integration areas, although the source of input is unknown at present.

Animals↗

[Radiation dose to the finger during injection of short-lived radionucleids in nuclear medicine (author's transl)].

The increasing use of short-lived radionucleids has shifted much of the radiation from the patient to the personnel. The purpose of this investigation, therefore, was to ascertain the greatest possible radiation dose to the fingers during injection of short-lived radionucleids. Basis for radiation measurements were small ionisation chambers attached to plastic syringes filled with radio-active material. By examples of typical situations, it was shown that the legally permissable values for partial body exposure may be exceeded. The necessity for using screening of the syringes is stressed. A simple method for making screening cylinders out of Wood's metal is described.

Fingers↗

["Massfunktionen" as limit conditions of an optimization scheme for the telecobalt therapy (author's transl)].

The basic ideas of the "Score-Funktionen-Modell" of Hope and his collaborators are used for the establishment of the first stage of an optimization scheme for the telecobalt therapy. The new "Massfunktionen" for the telecobalt therapy are limit conditions for the criterion of the optimum, i.e. the dose distribution in a body section. The "Massfunktionen" are an analytic registration of parameters for the dose distribution such as dose homogeneity in the focal region and sparing of the subcutaneous tissues, the radiosensitive organs and the sound surroundings of the tumor. The functions are derived from the dose conditions in the irradiated body section. At the actual stage of development of the optimization scheme, these functions allow to decide whether an irradiation scheme is acceptable or not.

Cobalt Radioisotopes↗

[Optimization in planning and application of 60 Co gamma irradiations - analysis of the problem (author's transl)].

As an aspect of the complex problem of optimization in therapeutical transmission of radiation energy to Man, the dose distribution within a cross-sectional area of the body is considered. For the judgement on optimal dose distributions, involving judgement on irradiation technique, boundary conditions are needed which encompass important parameters of a dose distribution (= criterion for optima). For computer-assisted optimization the boundary conditions are to be scheduled by an appropriate algorithm. The parameters describing a dose distribution are indicated. Practical utilization of computer-assisted optimization of dose is represented by means of two optimization schedules.

Cobalt Radioisotopes↗

[Statement of the bioptic diagnostic in intrathoracic sarcoidosis--team work of 6 lung hospitals of the GDR (author's transl)].

A nearly nation-wide team-work of six chest hospitals was made with 4284 patients to analyse all performed diagnostic procedures up to the present. Its frequency and diagnostic importance in relation to the radiographic stages of the disease were examined. Especially the procedure of bronchologic examination, having been partly underrated with the morphological ascertainment of sarcoidosis, are now purposefully analysed. This showed that also with perbronchic punction-biopsy and bronchoscopic excision morphologically confirming of the diagnosis was possible at a high percentage. On the other side the right diagnosis was made clinically before bioptic procedures in the majority of the patients. The overall conclusion is that, according to the experiences made in our hospitals, the relatively harmless bronchologic procedures are in general sufficient to obtain bioptic verfication of the diagnosis "sarcoidosis". Other bioptic operations like mediastinoscopy or lung biopsy can be restricted to cases with reasonable doube of the diagnosis.

Biopsy, Needle↗