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Biomedical subjects

M Kino

Publications and source records attributed to M Kino.

At least 109 records · Page 6Linked to original sources
PubMed1977

Contrast nasopharyngography.

Contrast nasopharyngography was performed in 25 cases of nasopharyngeal lesions, 15 of which were carcinoma, six malignant lymphoma, and four benign lesions including neurofibroma, haemangioma, angiofibroma and tuberculosis. Nasopharyngography was also performed in 22 cases with extranasopharyngeal lesions, including nine of head and neck malignant lymphoma and 13 of tumours originating in adjacent organs. To describe the extent and site of the tumour, the nasopharyngeal walls were labelled segment 1 to 15 on axial and lateral views. The lateral skull films were negative in five of eight small malignancies involving no more than five wall segments, and also negative in six of 10 cases of unilateral involvement. Small lesions involving the unilateral fossa of Rosenmueller and/or the superolateral wall were frequently undetected. Nasopharyngography is indicated in cases where clinical suspicions of a lesion remain after a normal straight film. When malignancies were treated with radiation therapy a pre-irradiation nasopharyngogram clearly depicted the site and extent of the disease, and a post-irradiation study showed a marked shrinkage of the tumour mass and/or markedly improved raggedness of the wall of the nasopharynx. Four benign lesions showed large space-occupying lesions. In the case of tuberculosis, for example, the nasopharyngeal cavity was totally obliterated by the granulomatous tissue. In nine cases of malignant lymphoma involving the neck nodes or the palatine tonsil, the nasopharyngogram was normal.

Contrast Media↗
PubMed1976

Auscultatory perception of the fourth heart sound: effects of interval form fourth to first sound (S4-S1) and aging.

A clinically heterogeneous group of 48 subjects (aged 19 to 76 years) were searched for a fourth heart sound (S4) by three independent "blind" auscultators. Phonocardiograms recorded immediately after auscultation were measured by another "blind" observer. An S4 was identified in 32 subjects (67 per cent) in phonocardiograms with nominal filter peaks of both 70 and 35 hertz. Results in these subjects revealed two groups by auscultatory performance: those with an "easily heard" and those with an "easily missed" S4. Subjects with an "easily missed" S4 were significantly younger than those with an "easily heard" S4 (31.2 +/- 2.8 years versus 50.0 +/- 4.0 years, P less than 0.001). P-R and P-S4 intervals and relative amplitude of S4 (ratio of fourth to first heart sound [S1] amplitude) were not significantly different in the two groups. Splitting of the first heart sound (S1) was observed more frequently in the phonocardiogram of patients with an "easily missed" S4, but this trend did not reach statistical significance. The interval between S4 and the low frequency component of S1 was significantly short in those with an "easily heard" S4 (49.4 +/- 4.1 msec versus 70.0 +/- 5.0 msec, P less than 0.005). The mean S4-S1 (low frequency component) interval for the group with an "easily heard" S4 approximated 1 cycle length for S4 vibrations, a finding consistent with temporal acoustic summation. An alternate hypothesis is modification of S1.

Adult↗
PubMed1976

Noninvasive differentiation of cardiomyopathy from coronary disease; pulse transmission time and systolic time intervals.

Systolic time intervals and central pulse transmission time were compared in cardiomyopathy (CM) patients and age-and sex-matched patients with coronary artery disease (CAD). Significant differences were found in pulse transmission time (shorter in the CAD patients (p less than .001) and in the pre-ejection period (p less than .001), ejection time index (p less than .05), and in the ratio of the pre-ejection period to the left ventricular ejection time (p less than .001); all were markedly abnormal in the CM group. Pulse transmission time differences may have been the result of more generalized arteriosclerotic disease in the CAD patients. It appears that both systolic time intervals and pulse transmission time clearly distinguish CM from CAD.

Cardiomyopathies↗
PubMed1976

Clavicular Auscultation. Preferential clavicular transmission and amplification of aortic valve murmurs.

Clavicular transmission of aortic valve murmurs was investigated in 15 consecutive patients. In all patients, transmission to the clavicle of aortic systolic murmurs was detected both by auscultation and by phonocardiographic studies. Of seven patients with aortic diastolic murmurs, auscultation revealed clavicular transmission in six, but only four were recordable. There was increased murmur amplitude over the clavicle in 13 out of 15 cases. In contrast, murmurs were attenuated over the subclavian artery in eight out of nine and over the carotid artery in nine out of 11 patients. We conclude that clavicular auscultation regularly discloses aortic valve murmurs. The aortic systolic murmurs are consistently propagated to the clavicle, where they are usually conspicuously amplified. Aortic systolic murmurs are less frequently transmitted to the carotid and subclavian arteries, where they are usually considerably attenuated. Clavicular auscultation appears to be more rewarding than the traditional search for transmission of aortic murmurs to the carotid artery.

Aortic Valve Insufficiency↗