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Biomedical subjects

M Khawaja

Publications and source records attributed to M Khawaja.

6 recordsLinked to original sources

Poverty.

This glossary addresses the complex nature of poverty and raises some conceptual and measurement issues related to poverty in the public health literature, with a focus on poor countries.

Health Status↗

The recent rise in Palestinian fertility: permanent or transient?

The purpose of this paper is to describe trends in fertility and fertility change in the West Bank and Gaza Strip during the years 1968-1992, with a particular focus on the recent rise in fertility. The paper is based primarily on vital registration data. The findings show that the fertility transition has been well underway in the West Bank since 1985, with a lull during the Intifada period. No indication of a fertility transition in the Gaza Strip was found. An examination of the age pattern of fertility reveals that Palestinian fertility has been increasingly shifting toward younger ages, with a particular concentration in the age group 15-24 during the Intifada period. A decomposition analysis of the fertility rates shows that the recent rise in fertility is essentially due to changes in marital structure, but also to increased fertility within marriage among younger women. No evidence of increased fertility among older women is found. Some implications of the findings are discussed.

Arabs↗

Intravesical administration of radiolabelled tumour-associated monoclonal antibody in bladder cancer.

Considerable progress has been made over the past decade in the use of tumour-associated monoclonal antibodies (mAbs) as carriers of cytotoxic agents in the management of several malignancies. In the present study we investigated the tumour localization and biodistribution of the mAb HMFG1 to bladder cancer following intravesical administration. HMFG1, which has been raised against the polymorphic epithelial mucin (PEM), was labelled with 125I and administered intravesically 2 h and 24 h before cystoscopy. During cystoscopy, biopsies were taken from the normal bladder and the malignant lesion. Tissue samples were tested for HMFG1 immunostaining and for radioactivity with the use of a gamma-counter. The mean ratio of tumour to normal uptake for 125I-HMFG1 was 5.81 +/- 1.23, at 2 h and 2.17 +/- 0.42 at 24 h. No radioactivity was detected in the blood. We conclude that HMFG1 could be used intravesically for the successful delivery of a cytotoxic agent.

Administration, Intravesical↗

AIDS clinic at the ACI.

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Acquired Immunodeficiency Syndrome↗