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Biomedical subjects

M Kelner

Publications and source records attributed to M Kelner.

24 records · Page 2Linked to original sources

Extraction of acidic drugs from water and plasma: study of recovery with five different solvents.

The recovery of 28 acidic drugs from water and plasma was investigated spectrophotometrically using five different solvents for extraction: hexane, diethyl ether, toluene, n-butyl chloride, and chloroform. Nine barbiturates, three sulfonamides, four diuretics, and twelve other acidic drugs were studied. As classes, the barbiturates, the sulfonamides, and the diuretics were optimally extracted with diethyl ether from both water and plasma, while considerable variation in recovery was noted among solvents for the other drugs. In general, recoveries from water were higher than those from plasma with most solvents, except for the sulfonamides for which recoveries were often better from plasma. Extraction recoveries for the individual drugs are tabulated and compared.

Barbiturates↗

Discharge planning in mental health: the relevance of cognition to community living.

OBJECTIVE: The purpose of this study was to investigate the relationship between cognitive disability and performance of daily living skills and stability of cognitive level after discharge in a sample of adult psychiatric inpatients (N = 40). METHOD: The Allen Cognitive Level Test-90 (ACL-90) was administered at time of discharge (Time I) and at 21 days to 28 days after discharge (Time II). The self-report version of the revised Routine Task Inventory (RTI-2) was also administered at Time II. RESULTS: No significant correlation was found between the ACL-90 at Time I and the RTI-2 scores; however, significant correlations were found between the ACL-90 scores at both times and between the ACL-90 score at Time II and the RTI-2 scores. CONCLUSION: The findings suggest that cognitive level remains relatively stable over a 1-month period in the postacute stage of a psychiatric illness. Cognitive level and performance of daily living skills are related, but the relationship is sensitive to time. Implications for occupational therapy assessment include recognizing the temporal constraints of functional assessments and refining instruments to be more sensitive to performance of familiar tasks, taking into consideration client adaptation to exigencies.

Activities of Daily Living↗

The career paths of MHSc graduates in health promotion.

There is much support for health promotion in Canada, but not much is known about the various academic programs in this field or of their impact on the practice of community health. A census survey was conducted in 1991 to determine the career paths of graduates of the MHSc program in Health Promotion at the University of Toronto. Findings from the study indicate that the career paths of graduates change following completion of their degree. They are more likely to work in health organizations other than hospital or treatment settings, to have more responsibility and authority in their positions as reflected by changes in job titles and to utilize a wider range of health promotion strategies and methods in their work following graduation. The findings indicate that graduate training in health promotion has a positive effect on the planning, implementation and evaluation of community health programs.

Career Mobility↗