Comparisons and cross reactions of nitrogenase from Klebsiella pneumoniae, Azotobacter chroococcum and Bacillus polymyxa.
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Biomedical subjects
Publications and source records attributed to M Kelly.
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A total of 151 men charged with drunkenness with or without aggravations were interviewed immediately after their appearance before the magistrates. The survey was conducted in two Metropolitan courts; one in an area frequented by vagrants, and the other in a mixed middle-class and working-class area.Few of the offenders were casual roisterers and the majority had a serious drinking problem. Half the offenders showed evidence of chemical dependence on alcohol as determined by morning shakes, morning relief drinking, amnesias, inability to stop drinking, and hallucinatory experiences.The majority of the offenders were suffering from gross social isolation.Existing ways of dealing with such men seem inadequate. A rehabitation service is needed, with hostel accommodation, and particular attention should be paid to first offenders.
1. Nitrogen-fixing preparations from Azotobacter chroococcum reduced substrates with the following K(m) values: methyl isocyanide, 1.8x10(-4)m; ethyl isocyanide, 2.5x10(-2)m; cyanide ion, 1.4x10(-3)m; acetylene, 1.2x10(-4)m. 2. Nitrogen, carbon monoxide or hydrogen competitively inhibited isocyanide reduction with the following K(i) values: hydrogen, 1.3x10(-3)m; carbon monoxide, 6.8x10(-6)m; nitrogen, 4.3x10(-4)m. 3. Living nitrogen-fixing bacteria, and isolated clover nodules, formed methane from methyl isocyanide. 4. These results are discussed in relation to other work and possible mechanisms of nitrogen fixation.
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BACKGROUND: Macroglossia is an unusual symptom in primary care. It may be an indicator of an underlying plasma cell dyscrasia or multiple myeloma in the elderly. AIM: To describe such a case of multiple myeloma. RESULTS: A 69-year-old man,with a recent history of bilateral carpal tunnel repair, presented to his GP with progressive macroglossia. This was eventually diagnosed as being due to amyloidosis, secondary to multiple myeloma. CONCLUSION: Physicians should be aware of the association between macroglossia, carpal tunnel syndrome and multiple myeloma in this age group.