The neural mechanism of cyclopropane anesthesia in the rabbit.
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Action Potentials↗
Biomedical subjects
M Kawamata
Publications and source records attributed to M Kawamata.
The effects of several anesthetic agents on the neuronal reactive properties of thalamic relay nuclei in the cat.
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Amines↗
[Experimental study on infant nutrition (young animals). 40. Effect of air-oxidized linoleic acid and oleic acid to growth of young rats].
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Air↗
A neurophysiologic study of ketamine anesthesia in the cat.
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Anesthetics↗
[Glucuronic acid metabolism. 22. Pharmacological studies on thiopental sodium anesthesia. Effects of glucuronolactone on thiopental sodium anesthesia].
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Anesthesia, General↗
[Pharmacological studies on thiopental sodium anesthesia. Studies on the "Lamson's effect" induced by glucose].
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Anesthesia, General↗
[Pharmacological study of a protease TSP-X produced by Serratia sp.E 15].
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Animals↗
The effects of midazolam and ketamine on D-tubocurarine-induced twitch depression in septic rat diaphragm.
The aim of this study was to elucidate the effects of midazolam and ketamine on neuromuscular blockade induced by non-depolarizing muscle relaxants (NDMRs) under the condition of sepsis induced by panperitonitis. A CLP operation (laparotomy, cecal ligation, and puncture of the cecum; septic group) or sham laparotomy (sham group) was performed on rats under O2-isoflurane anesthesia. At 18 hours after the operation, isometric twitch tensions of rat nerve-hemidiaphragm preparations elicited by indirect or direct stimulation at 0.1 Hz were measured. Midazolam enhanced the dTc (1 microM)-induced twitch depression (p < 0.05) at a high concentration (10 microM) in the septic group but not in the sham group. Ketamine enhanced the dTc (1 microM)-induced twitch depression in the sham group (p < 0.01) but not in the septic group. Midazolam and ketamine had no effect on directly elicited twitch tensions in either group. The results indicate that sepsis facilitates the midazolam-induced enhancement of the neuromuscular blocking effect of dTc but, conversely, inhibits the ketamine-induced enhancement. Sepsis elicits manifold alterations in the influence of intravenous anesthetics and sedatives on NDMR-induced neuromuscular blockade.
Anesthetics, Dissociative↗