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Biomedical subjects

M K Walker

Publications and source records attributed to M K Walker.

58 records · Page 4Linked to original sources

Medication safety: a protocol for nursing action. NICHE Faculty.

Medication consumption represents a significant source of adverse events, therapeutic misadventure, and toxicity to older Americans. Estimates indicate that as many as 25% to 40% of all U.S. prescriptions are written for older people. Hospital admission rates for drug-related problems and toxicity in elders approach 33% in some studies. This article addresses some of the physiological changes associated with aging and their effects on the absorption, distribution, and metabolic fate of common medications in elders. High-risk medications are identified, and strategies for combating their adverse effects are suggested.

Aged↗

Maternal reactions to fetal sex.

A descriptive design was used to characterize maternal reactions to the knowledge of fetal sex based on sex preference. The sample was 88 females with singleton pregnancies who had had an amniocentesis for fetal chromosome studies and met the following sample criteria: (a) Fetal karyotype and other studies were normal, (b) knowledge of fetal sex was desired, and (c) sex preference had been established. Maternal reactions to the knowledge of fetal sex were ascertained through a questionnaire I developed and that participants answered in writing. Sample characteristics were summarized using descriptive statistics, and the mothers' narrative responses were subjected to content analysis. Maternal sex preferences were equally split between male and female. However, there were differences in the way mothers who attained and mothers who did not attain their preferred fetal sex spoke of their fetuses.

Adult↗

Validation of tardive dyskinesia as measured on the Dyskinesia Identification System--Coldwater.

Identification and description of tardive dyskinesia have been hampered by the absence of systematic studies assessing the psychometric properties of existing instruments. The purpose of this study was to establish construct validation of one of these instruments, the Dyskinesia Identification System--Coldwater. Cross-sectional prevalence assessment data of 519 institutionalized mentally retarded persons were used. The 34 items of this instrument were subjected to exploratory factor analysis. A six-factor orthogonal solution was selected. Multiple regression analyses supported the established relationships of demographic variables, such as age and sex, with the tardive dyskinesia scores generated by the instrument.

Adolescent↗