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Biomedical subjects

M K Cline

Publications and source records attributed to M K Cline.

3 recordsLinked to original sources

Maternal infections: diagnosis and management.

An understanding of the common infections that occur during pregnancy is crucial for prenatal care providers. This article discusses specific screening and diagnostic tests, along with appropriate treatment regimens for common bacterial, viral, protozoal, and fungal infections that occur during pregnancy. Additionally, methods to reduce the likelihood of infection, such as preconception immunization, are reviewed.

Anti-Bacterial Agents↗

Keeping normal labor normal.

Labor and delivery have been viewed by physicians as processes that can and must be managed by physicians for their pregnant patients. This article asserts that most births do not need to be interventionally managed and that a birth attendant's highest order skill is knowing when and how not to intervene. Further, the article looks at what birth interventions are likely to keep normal labor normal. The authors propose a new paradigm: The 10 "P's" of keeping normal labor normal.

Delivery, Obstetric↗

Papanicolaou smear discrepancy: resolution by review.

BACKGROUND: Discrepancy between Papanicolaou smears and colposcopically directed biopsies often creates a treatment dilemma, especially when the cytologic specimen suggests a higher grade lesion than the histologic specimen. A method of side-by-side review using the Bethesda System was evaluated as a means of resolving this discrepancy between cytologic and histologic specimens. METHODS: By means of a retrospective chart review, we selected 150 patients undergoing colposcopic evaluation for abnormal cytologic findings. Thirty-eight patients had higher grade lesions on cytologic examination than on histologic examination. Twenty-four of these patients had both cytologic and histologic slides available, and these specimens were evaluated in a blinded review by a single pathologist using the Bethesda System of classification. RESULTS: Reevaluation yielded resolution of discrepancy in 19 of 24 cases, a 79.2 percent resolution. CONCLUSION: Review of cytologic and histologic specimens by an experienced pathologist using the Bethesda System can resolve many of the cases in which the cervical lesion is considered to be of a higher grade by cytologic examination than by histologic examination.

Biopsy↗