Imaging case of the month. Cerebral ventricular dilation and diaphragmatic elevation in congenital myotonic dystrophy.
Explore the source record for details and available documents.
Brain↗
Biomedical subjects
M K Caglar
Publications and source records attributed to M K Caglar.
Alpha-fetoprotein normal values.
Explore the source record for details and available documents.
Age Factors↗
Successful treatment of superior vena cava syndrome with urokinase in an infant with a central venous catheter.
An infant with superior vena cava syndrome due to thrombus formation in the superior vena cava, sourced from a central venous line, was treated with urokinase. It was used in a loading dose of 250,000 units/1.73 m2/15 min, followed by continuous infusion of 125,000 units/1.73 m2/h for three days. After two days of urokinase treatment, the clinical signs of superior vena cava syndrome completely disappeared. No bleeding complication was observed.
Catheterization, Central Venous↗
Determination of serum ferritin in the evaluation of iron depletion and iron over load in chronic twin-to-twin transfusion syndrome.
In two pairs of twins with twin-to-twin transfusion syndrome serum ferritin levels were determined in order to estimate body storage of iron. Serum ferritin levels in the donor twins were found to be markedly lower than in the recipients and were below the lower limit found in normal neonates. One of the recipients was hydropic. His ferritin level was elevated far above the upper limit of normal. These findings support the hypothesis that in chronic twin-to-twin transfusion, depletion of iron stores occurs in the donor while the recipient suffers from iron overload. Determination of ferritin levels may be useful in the investigation of the twin-to-twin transfusion syndrome.
Anemia, Neonatal↗
Pyridoxine in the treatment of tetanus neonatorum.
A prospective study has been conducted to assess the efficacy of oral pyridoxine in the treatment of neonatal tetanus. A little reduction in mortality was observed by adding pyridoxine to the conventional therapy. The mortality in this group was 50.0% as compared to 62.5% in controls. This result did not confirm the ones in the literature. This could be sourced from the fact that additional infection was 50.0%.
Developing Countries↗
Neurobrucellosis in children.
Although the neurological symptoms in brucellosis are frequent, nervous system involvement is uncommon. In addition, blood and cerebrospinal fluid may not show growth of Brucella in culture. For these reasons brucellosis may not be considered; hence correct diagnosis of the disease may be delayed. We have presented three cases of leptomeningitis due to brucellosis where diagnosis was delayed one to two months and was correctly made in two cases only after bone marrow aspiration culture.
Adolescent↗
Cerebrospinal fluid lactic dehydrogenase activity in children with acute lymphoblastic leukemia treated for cranial prophylaxis.
Total lactic dehydrogenase (TLDH) activity in cerebrospinal fluid (CSF) has been prospectively studied in order to determine whether it could be a biochemical marker for brain damage due to cranial prophylaxis in children with acute lymphoblastic leukemia (ALL). TLDH activity has been measured in 15 patients before prophylaxis, in 15 patients after the prophylaxis which consisted of cranial radiotherapy (2400 rads) and intrathecal methotrexate (0.5 mg/kg-dose, 5 doses), in 8 patients after radiotherapy alone (2400 rads) and in 9 patients after intrathecal methotrexate (0.5 mg/kg-dose, 5 doses) alone. TLDH activity in CSF of combined prophylaxis group has been found to be higher than the ones before study (p less than 0.05). There were insignificant elevations of TLDH activity in the other two groups (p greater than 0.05; p greater than 0.05). This result indicated combined cranial prophylaxis seemed to be more toxic than the other prophylaxis regimens when they were used alone.
Adolescent↗