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Biomedical subjects

M Julien

Publications and source records attributed to M Julien.

At least 109 records · Page 6Linked to original sources

Focal hemorrhagic necrosis of the liver. A clinicopathological entity possibly related to oral contraceptives.

A 44-year-old woman who had been taking oral contraceptives for 10 yr developed abdominal pain and abnormalities of liver tests, which led to the discovery of multiple filling defects on liver scan and of large hepatic zones of decreased density on computerized tomography of the abdomen. These abnormalities were due to sharply demarcated areas of hepatic multilobular hemorrhagic necrosis, associated with marked changes of liver arterioles and small hepatic veins. Since oral contraceptives have been incriminated in the genesis of hepatic vascular alterations, the possible relationship between focal hemorrhagic necrosis of the liver and these agents is suggested.

Adult↗

[Splenectomy for hematologic indications. Indications, early results (author's transl)].

In the light of their personal experience of 1,036 splenectomies, the authors review the hematological diseases which still require surgery, viz. certain hemolytic anemias, idiopathic thrombocytopenic purpura, Hodgkin's disease under certain conditions, and sometimes the splenic lesions in certain malignant blood diseases; they analyse their results. Thanks to close collaboration between hematologists and intensive care specialists, the mortality has been reduced to 1.35 p. cent and the morbidity to 3.46 p. cent which leaves 95.19 p. cent without any immediate postoperative complications. The late results depend on the initial disease process.

Anemia, Hemolytic↗