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Biomedical subjects

M Jeffcoat

Publications and source records attributed to M Jeffcoat.

10 recordsLinked to original sources
PubMed1996

Analysis of consecutively placed loaded root-form and plate-form implants in adult Macaca mulatta monkeys.

The present paper describes 36 consecutively treated non-human primates (Macaca mulatta) as part of a balanced block design study to examine osseointegration in root- and plate-form implants prepared by atraumatic preparation of bone. Clinical measurements around selected teeth and digital radiology were utilized to monitor periodontal disease and bone loss around root- and plate-form implants which were loaded with a fixed prosthesis. Results indicate that once monthly regimen of scaling and root planing can prevent attachment loss in natural teeth, serving as abutments of loaded bridges. Root-form implants exhibited a significant loss of crestal bone height during the first year (P < 0.03) while plate-form implants showed less loss in bone height. There was an increase in bone mass over time for root-form or plate-form implants. Both root-form and plate-form implants provided radiographic evidence of osseointegration in loaded bridges.

Alveolar Bone Loss↗
PubMed1994

Evaluation of consecutively placed unloaded root-form and plate-form implants in adult Macaca mulatta monkeys.

The present paper describes 18 consecutively-treated non-human primates (Macaca mulatta) as part of a balanced block design study of 36 animals to examine osseointegration in root- and plate-form implants prepared by atraumatic preparation of bone. Clinical measurements around selected teeth and digital radiology were utilized to monitor periodontal disease and bone deposition around the unloaded implants. Once a month scaling procedures were utilized as a means of preventing further advance of periodontal disease. Results indicate that once-monthly regimen of scaling and root planing can prevent attachment loss of natural teeth and will not interfere with the healing of either type of implant; once-monthly scalings produce significant reduction in redness (P < .05) and reduced probing depths (P = .01). A second finding is that both root and blade implants show radiographic evidence of osseointegration in this primate model. The quantitative analysis demonstrates bone gain is not stabilized until 6 months after healing. The data may indicate that occlusal loading of mandibular implants at 3 months may be premature.

Alveolar Bone Loss↗
PubMed1993

Chemical plaque control: how do you advise your patients?

Certain antiplaque and antigingivitis agents have proven efficacious in the control of plaque and gingivitis. To adequately assess the magnitude of the effect that is to be expected in clinical practice, the dentist must take into account the experimental design in order to extrapolate the results of the clinical trial to the target patient population. This paper reviews the strengths and weaknesses of major clinical trial designs in light of their relationship to the results dentists can expect in clinical practice.

Anti-Infective Agents, Local↗
PubMed1993

When to treat: when to refer.

For each patient with periodontal disease, the general dentist must decide when to treat and when to refer. The outcome of this decision is critical to the long-term control of progressive bone and attachment loss. In order to make this decision, the dentist must consider patient related factors, dentist related factors, and the entire range of periodontal therapy available. The purpose of this paper is to review the key factors inherent in this decision making process. The range of therapeutic modalities which should be considered by the dentist are presented for specific periodontal diseases. A rationale for treatment or referral of each specific periodontal disease is given.

Decision Making↗
PubMed1991

Planning interactive implant treatment with 3-D computed tomography.

Treatment planning for dental implants presents special challenges to the dentist. The authors review the conventional radiographic and non-radiographic methods for the assessment of the implant site. A new dental interactive treatment planning program under development at the University of Alabama School of Dentistry Department of Periodontics is described.

Alveoloplasty↗
PubMed1988

A perspective on periodontal disease activity measurements.

Studies utilizing serial standardized periapical radiographs for measurements of alveolar bone height and for digital subtraction and changes in clinical probing attachment level have suggested that adult periodontitis may exhibit periods of exacerbation and remission at specific sites. The use of such serial examinations for the determination of disease activity must be interpreted with caution since the different methods for the assessment of disease activity have different levels of sensitivity and specificity and because such sequential methods integrate disease activity and do not provide an instantaneous measure of activity. An ideal test for disease activity would approach an instantaneous measure of disease activity and would not integrate activity over time.

Alveolar Process↗