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Biomedical subjects

M Jamet

Publications and source records attributed to M Jamet.

21 records · Page 2Linked to original sources

[Enzymatic fibrinolytic agents].

Urokinase (UK) and streptokinase (SK) transform plasminogen into plasmin by rupture of a ARG-VAL bond and the liberation of a peptide with a molecular weight of 6000 to 8000. Urokinase is a physiological activator with a direct action. By contrast, streptokinase is an enzyme of bacterial origin and two hypotheses may be advanced to explain its mechanism of action: the formation of a SK-plasminogen complex capable of activatiing new molecules of plasminogen or the formation of a SK-plasminogen complex within which plasminogen is transformed to plasmin.

Endopeptidases↗

[Fibrinolysis].

A large number of methods may be used in the study of fibrinolysis. They are either so-called direct when they demonstrate abnormal lytic activity and indirect when they analyse the results of this activity. In practical terms, the examinations used most widely are the euglobulin lysis test, evaluation of the plasminogenplasmin pair, and estimations of fibrinogen and of its breakdown products.

Blood Coagulation Tests↗