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Biomedical subjects

M Jaeger

Publications and source records attributed to M Jaeger.

At least 91 records · Page 5Linked to original sources

[A study of prescriptions for psychotropic drugs at a French psychiatric hospital].

The prescribing habits were studied in a psychiatric hospital which provides services for one district of Paris. The sample consisted of 175 inpatients. A mean of 2.1 psychotropic drugs was prescribed per patient, and more than two-thirds received two psychotropic drugs or more. Almost one-half had a PRN order. Major tranquilizers were frequently used in patients not having a psychotic disorder and were associated to anticholinergic drugs in 55% of the cases. Factors associated with drug prescriptions were diagnosis, age and unit of treatment. Our results are similar to those of previous studies on excessive polypharmacy. The discussion draws attention on the need to obtain data on the rationale for prescribing and the response to treatment. Emphasis is placed on the potential usefulness of studying drug prescriptions for psychiatric practice.

Adolescent↗

[The risk of sudden death in sports practice--can it be diagnosed and reduced?].

The sudden death of a sportsman in full action is fortunately rather uncommon. Nevertheless, it is all the more frightening, as it befalls unexpectedly someone who is seemingly in full health. Moreover, this type of accident, essentially a cardiac event, strikes more often competitive athletes than leisure sportsmen, who are submitting themselves to more moderate exertions. The mechanism leading to death is in most cases a heart rhythm problem ending in ventricular fibrillation. Its origins are generally a cardiomyopathy or an inborn structural anomaly of the heart in young subjects. In men over 30 years of age, most deaths can be explained by degenerative coronary disorders. It is important to note that 93% of sudden death victims related to exertion in sports are men, even if women form 45% of practising sports people. A large part of the decreased had already a functional disorder, often angina, before the tragic event took place. 38% of this group even took medical advice from a cardiologist. We may thus consider that a fraction of these deaths could be prevented through diagnosis and subsequent treatment. Therefore, sports people should be better informed on the risks they incur in not taking care of themselves. This information has to be distributed on a large scale. With regard to the other cases, we should examine which detection tests are to be discussed and used. They may involve a financial problem, but should nevertheless be considered carefully.

Adult↗

The effect of ionizing radiation on advanced life support medications.

Advanced life support medications stored in emergency department stretcher areas, diagnostic radiology rooms, and radiotherapy suites are exposed to ionizing radiation. We hypothesized that radiation may decrease the potency and thus the shelf life of medications stored in these areas. Atropine, dopamine, epinephrine, and isoproterenol were exposed to a wide range of ionizing radiation. The potency of the four drugs was unaffected by levels of radiation found in ED stretcher areas and high-volume diagnostic radiograph rooms (eg, chest radiograph, computed tomography, fluoroscopy). The potency of atropine may be reduced by gamma radiation in high-use radiotherapy suites. However, dopamine, epinephrine, and isoproterenol were unaffected by high doses of gamma radiation. Atropine, dopamine, epinephrine, and isoproterenol may be safely kept in ED stretcher areas and diagnostic radiology rooms without loss of potency over the shelf life of the drugs.

Atropine↗

[Electrocardiogram of the athlete].

The EKG of an athlete may present various alterations, appearing with time and representing the normal cardiac repercussion of an intense and regular physical activity. The vagotonia linked to this activity explain rhythmic abnormalities and conduction alterations. The left ventricular hypertrophy, often noticed, is probably more frequent actually than on the EKG. As for repolarization disorders, at rest or exertion, one must be cautious for their interpretation, since they may have been induced by sport but a coronaropathy remains possible. A routine EKG can also disclose unexpected abnormalities as in anyone; the particular case of complete A-V blocks and WPW is considered here.

Arrhythmias, Cardiac↗

[An unusual protodiastolic bruit: the click of an aberrant mitral cord].

An asymptomatic adult woman without clinical cardiac disease had an unusual early diastolic heart sound. All usual causes of this finding were excluded: it was not a delayed pulmonary component of the second heart sound, a mitral or tricuspid opening snap, an early diastolic third heart sound or a pericardial vibration. The only apparent cause was a left ventricular false tendon extending from the septal endocardium to the left ventricular free wall, demonstrated by 2D echocardiography. This type of aberrant intracardiac band has already been described but the possibility of early diastolic stretching of this structure giving rise to an abnormal early diastolic sound does not seem to have been previously reported.

Female↗