[Solitary plasmacytoma of the jejunum].
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Biomedical subjects
Publications and source records attributed to M Jaeger.
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If the anamnesis is not conclusive for a definite diagnosis of angina pectoris or if a complementary test is adviseable the ECG, which is hardly ever significant at rest, can become very significant under the influence of physical activity. The easiest methodology is a bicycle ergometer or a treadmill performance test which can be performed under ideal safety conditions and which gives the best possible information. Compared to the coronarography results in 319 patients, the performance test at either maximum heart rate or up to the appearance of the typical electrocardiographic alterations was positive in 75.5% of the cases. It is less instructive if the test is not systematically exhaustive. Its validity also varies depending on the number of coronary arteries affected by stenosis, on the type of the angina pectoris, and the aspect of the ECG at rest. If the test is performed up to the maximum heart rate, its sensitivity is superior to the ones using lsoprenaline or right atrial pacing as a means for influencing the ventricular function.
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Using electromagnetic articulography, the lips, the tip of the tongue, and the tongue dorsum were tracked during repetitions of the syllables [pa], [ta] and [ka] in 10 speakers with dysarthria following severe traumatic brain injury and in 10 age-matched control subjects. When asked to produce the syllable trains as fast as possible, the patient group showed a rather homogeneous pattern of movement abnormalities including prolonged syllable durations and reduced peak velocity/amplitude ratios. Most presumably, limited speed generation gives rise to the impaired ability to increase speech rate. During the habitual speaking condition, reduced velocity/amplitude ratios were restricted to the tongue tip and tongue dorsum. Obviously, the tongue and the lips are differentially affected in dysarthria following severe traumatic brain injury.
We tested the applicability of the Goettinger Hoarseness Diagram (GHD) for quantitative evaluation of voice disorders after severe traumatic brain injury (TBI) and compared the obtained data with those from established voice analysis systems such as the Multi-Dimensional Voice Program (MDVP), electroglottography (EGG) and perceptual ratings using sustained vowel productions from 10 patients with TBI dysarthrophonia at late stages postinjury and of 10 healthy control speakers. Statistical analyses revealed significant intergroup differences with respect to various acoustic and perceptual measures, i.e., irregularity component, noise component, noise-to-harmonic ratio, shimmer, jitter, roughness, creakiness, strained-strangledness, hypernasality. By contrast, the considered EGG estimates, i.e., open quotient and speed quotient, did not allow for separation of patients and controls. In addition, the two GHD components exhibited close correlations to perceived roughness and creakiness, on the one hand, and breathiness and, to some degree, nasality, on the other, whereas the MDVP parameters failed to differentiate between these two perceptual modes of phonation.
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