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Biomedical subjects

M J Stiller

Publications and source records attributed to M J Stiller.

At least 37 records · Page 2Linked to original sources

Photography without film: low-cost digital cameras come of age in dermatology.

BACKGROUND: Photography is integral to the practice of dermatology. Digital imaging techniques have only recently been used to assess cutaneous disorders. Previously reported imaging systems have been both expensive and cumbersome. Consequently, they have failed to gain wide-spread acceptance. METHODS: We describe our experience using an inexpensive digital camera. Photographs taken with this portable digital camera (FotoMan) compare favorably to those obtained with conventional 35 mm cameras. RESULTS: This inexpensive digital camera provides photographs of acceptable quality for a variety of dermatologic applications. Images created with this system are available within minutes and are less expensive than traditional photographs. CONCLUSIONS: Digital imaging is a new and exciting development. The digital camera described is simple to operate and provides a useful alternative or adjunct to conventional photography.

Adult↗

Better dermatologic office photography: taking the photograph.

In a previous article we reviewed the questions every medical photographer must ask when looking through the viewfinder, as well as the difference between plastic surgical and dermatologic photography. We conclude by offering a mnemonic for the three views necessary in dermatologic photography: Location, Scan, and Detail, and by suggesting a technique for preadjusting the camera, lens setting, and flash that will guarantee consistent, high-quality clinical photos.

Dermatology↗

Better dermatologic office photography: getting started.

In an earlier paper, we defined a medical photograph as one that accurately maximizes clinical information while minimizing irrelevant data. This paper expands on this concept, providing specific hints to assist the practitioner in obtaining consistent high-quality clinical photos. We review the important question every medical photographer must ask when looking through the viewfinder as well as the difference between photography for practitioners of plastic surgery and dermatology.

Dermatology↗

Diagnostic ultrasound in dermatology: current uses and future potential.

Although ultrasound has been used for many years for a variety of medical diagnostic purposes, only recently have systems been designed that allow for its application to skin. High-resolution ultrasound systems now permit accurate, quantitative, noninvasive assessment of skin and cutaneous diseases. This technique will assist in the management of both inflammatory and neoplastic processes. Scans of skin obtained with a prototype high-resolution ultrasound system are presented. The computer-assisted creation of three-dimensional images from sequential B-mode scans is described.

Humans↗

Mucocutaneous leishmaniasis: a clinicopathologic classification.

BACKGROUND: Leishmaniasis, a chronic parasitic disease transmitted by Phlebotomus sandflies, affects millions of patients. Mucocutaneous leishmaniasis caused by Leishmania brasiliensis is endemic in much of South America. OBJECTIVE: Our purpose was to develop a system for staging mucocutaneous leishmaniasis on the basis of clinical, histopathologic, epidemiologic, and immunologic criteria. METHODS: Seventy-five Bolivian patients with mucocutaneous leishmaniasis were evaluated by history and physical examination; cutaneous, mucosal, and bone marrow biopsy specimens; and immunologic assessment. RESULTS: Mucocutaneous leishmaniasis may progress through three clinical stages: (1) the primary or cutaneous, (2) the cicatricial, and (3) the secondary or mucocutaneous stages. The primary stage can be further subdivided into three phases: lymphoplasmocytic, tuberculoid, and diffuse cutaneous phases. The secondary stage can also be subdivided into three phases: edematous, granulomatous proliferative, and granulomatous necrotizing stages. CONCLUSION: A classification or staging system enhances the ability to evaluate patients with mucocutaneous leishmaniasis and determine more accurately their prognosis and treatment.

Adult↗

Three-dimensional imaging for diagnostic ultrasound in dermatology.

BACKGROUND: Visual examination and cutaneous biopsies, two major tools in dermatologic diagnosis, do not provide structural information regarding the entire tissue volume. OBJECTIVE: Our purpose was to develop a high-resolution ultrasound system that quickly, with minimal operator interaction, displays structural data on the entire tissue volume. METHODS: A prototype ultrasound B-scan system was developed and operated at nominal center frequencies between 35 and 50 MHz, with computer processing of data to produce three-dimensional images. These images displayed as three-dimensional "blocks" can be sectioned to provide multiple images of internal structure (i.e., "acoustic biopsies"). RESULTS: B-scans and associated three-dimensional images were obtained from assorted skin sites in selected patients. CONCLUSION: This technique provides a valuable diagnostic tool that is now being further evaluated.

Adult↗

Diflorasone diacetate ointment 0.05% versus betamethasone dipropionate ointment 0.05% in moderate-severe plaque-type psoriasis.

We report the results of a 2-week double-blind, parallel clinical trial comparing two superpotent topical glucocorticosteroid ointments, diflorasone diacetate 0.05% and betamethasone dipropionate 0.05%, in psoriatic adults. Both corticosteroid ointments were fast acting and highly efficacious. 40 of the 44 patients who initially enrolled completed the trial. There were no statistically significant differences between the two glucocorticoids with respect to erythema, scaling, induration or the investigator's global evaluation after either 1 or 2 weeks of therapy. The level of patient satisfaction with the efficacy and cosmetic acceptability of these two category I glucocorticoids was similar. No systemic or local adverse reactions were noted.

Administration, Topical↗

Dental curettes: useful tools for obtaining nail material for mycologic examination.

Obtaining material, especially subungually, from suspected onychomycotic nails can be difficult and/or traumatic with instrumentation frequently utilized by dermatologists. Use of scalpel blades and standard dermal curettes is often awkward and/or traumatic to the nail bed. Large clippings require micronization with a nail mill or tedious processing with less specialized instruments prior to microscopic examination (potassium hydroxide preparation) and fungal culture. A mycologist at our institution has efficaciously utilized dental curettes to obtain powdery subungual material suitable for immediate mycological assessment. This nontraumatic technique is becoming increasingly popular among clinicians.

Curettage↗