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Biomedical subjects

M J Sternschein

Publications and source records attributed to M J Sternschein.

4 recordsLinked to original sources

Rare synchronous parotid tumors of different histologic types.

A review of the approximately 2000 parotid salivary gland tumors studied at the Columbia-Presbyterian Medical Center in New York from 1918 to 1978 showed that separate, synchronous neoplasms of different histologic types were found in the parotid gland in only 7 patients. In 6 of these patients, there was a clinically solitary mass; in the other patient, two separate nodules were palpated. In each case, subtotal or total parotidectomy was performed. On examination of the resected tissue, two separate nodules were identified grossly in three patients; in one, a benign mixed tumor and a mucoepidermoid carcinoma; in the second, a benign mixed tumor and a Warthin's tumor; and in the third, a mucoepidermoid carcinoma and a Warthin's tumor. In the remaining 4 patients, only one grossly evident tumor was found, including benign mixed tumor in 3 patients and a poorly differentiated adenocarcinoma in 1 patient. In each of these cases, the second tumor, discovered only microscopically, was a Warthin's tumor. Thus, in 6 of the 7 patients, the second neoplasm was a Warthin's tumor.

Adenolymphoma↗

Fibromatosis of the breast.

We have reviewed the Columbia-Presbyterian Hospital experience with fibromatosis of the breast, a most uncommon lesion that frequently mimics carcinoma. Very few examples of this rare lesion have been reported previously, and the lack of follow-up data has made it difficult to evaluate treatment. Five patients were cared for at the Columbia Presbyterian Medical Center and an additional 12 patients were reviewed after slides were sent for consultation. Complete clinical information and follow-up data were obtained in a total of 13 patients, three of whom had recurrences. There were no histologic features that served to distinguish those patients who had a recurrence from those who did not. While there were no recurrences when adequate excision was carried out, it is worth noting that we found one instance of spontaneous regression as well as two patients who did well despite the fact that tumor was found at the margin of the specimen. The results of this review suggest that the major problem facing the surgeon, once the diagnosis has been made, relates to the difficulty in defining the extent of the tumor in the breast. Careful orientation of the specimen and repeated use of frozen sections should make it possible to perform a complete excision and, at the same time, remove a minimum amount of breast tissue. Since fibromatosis is a benign process, the cosmetic impact of surgical therapy certainly deserves careful consideration.

Adolescent↗

Causalgia.

Causalgia is a distressing syndrome which should be diagnosed and treated promptly. A presumptive diagnosis can be made on the basis of the existence of burning pain, autonomic dysfunction and atrophic changes. Confirmation of diagnosis can be obtained by assessing the results of a sympathetic block. Some patients with causalgia may be mistaken for "hysterics" or "malingerers." Treatment may require physical and occupational therapy, analgesics, tranquilizers, sympathetic block or sympathectomy. The merits of adrenergic blocking agents, percutaneous electrical stimulation, dorsal column stimulation and acupuncture are still to be evaluated.

Adult↗