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Biomedical subjects

M J Rico

Publications and source records attributed to M J Rico.

41 records · Page 3Linked to original sources
PubMed1985

Cutaneous cryptococcosis resembling molluscum contagiosum in a patient with AIDS.

A 29-year-old Haitian man with the acquired immune deficiency syndrome (AIDS) developed disseminated cryptococcosis with an unusual cutaneous presentation. He had numerous hypopigmented papules over his face that clinically resembled molluscum contagiosum. To our knowledge, cutaneous cryptococcosis resembling molluscum contagiosum has not been previously reported. The patient had a T-cell defect consistent with AIDS and belonged to a high-risk group. To our knowledge, this is the second report of cutaneous cryptococcosis in a patient with AIDS.

Acquired Immunodeficiency Syndrome↗
PubMed1982

Microinvasive carcinoma of the vulva.

Thirty cases of microinvasive squamous cell carcinoma of the vulva were seen from 1972 to 1978 inclusive. They comprised 37.7% of 77 cases of squamous carcinoma of the vulva seen during this period of time. The results of analysis of multiple factors, including tumor depth and pattern of invasion, nuclear and histologic grade, volume, inflammatory response, presence of vascular invasion, and depth of invasion as compared to the depth of adjacent skin appendages and rete ridges are presented. Two patients were found to have inguinal lymph node metastasis: in one of these patients the tumor was deeper than the adjacent deepest skin appendages while in the second patient skin appendages were not adjacent to the tumor. These tumors measured 2.25 and 1.8 mm in depth, respectively. In both patients the tumor was of high nuclear grade and had a diffuse pattern of infiltration. No nodal metastases were found in patients whose tumors did not invade deeper than 1.5 mm or deeper than the adjacent deepest skin appendage. Tumors measuring 1.5 mm in depth had tumor volumes under 1,000 mm3. The only death from tumor that occurred in this series occurred in a woman who had a second primary tumor of the vulva following a local excision for her microinvasive carcinoma. The definition and measurements of microinvasive carcinoma of the vulva are discussed and an improved method of measurement is proposed.

Adult↗
PubMedDate not supplied

Composite keratohyaline granules in striate keratoderma.

The gross, light microscopic, and ultrastructural findings in a 55 year old man was striate keratoderma are presented. There was no family history of the disease. The lesions developed in his late teens and early adult years, and consisted of progressively worsening, raised, hyperkeratotic, linear plaques on the palm and volar surface of the third and fifth fingers bilaterally. There were also painful callosities on both heels, and thick, raised plaques on the heels and lateral plantar surfaces. The epidermis was papillomatous and acanthotic, with marked orthokeratosis, minimal parakeratosis, and a very thickened granular layer. No epidermolysis was seen. Electron microscopy showed increased tonofibrils in the stratum spinosum arranged in wavy, parallel bundles and a granular layer in which normal Odland bodies were present. However, the keratohyaline granules were large, with rounded borders and a striped, alternating, dark and light content characteristic of composite granules. There was diminished contact of the granules with tonofibrils. The transition to the stratum corneum was abrupt. The ultrastructural and genetic features of keratodermas, with special emphasis on the striate type, are reviewed.

Cytoplasmic Granules↗
PubMedDate not supplied

[The implantable endocavitary cardioverter-defibrillator: the initial and short-term results].

Utilization of endocavitary defibrillation electrodes avoids thoracotomy used in implantable cardioverter-defibrillator procedures, reducing associated morbi-mortality. In our institution we have used this approach in 16 patients during a two years period (July 1990-July 1992). Fifteen were males, with a mean age of 56.9 +/- 10.6 (range 32-73). Nine patients suffered ischemic cardiomyopathy, 4 non ischemic cardiomyopathy and in three there was no structural heart disease. Mean ejection fraction was 44.3 +/- 18.3% (range 20-73%). Clinical arrhythmia was ventricular tachycardia in 8 cases, ventricular fibrillation in 6 cases and both types in 2. Endocavitary implantation procedure was not completed in 3 patients, thus an open trans-sternal approach was performed. In 13 patients it was completed successfully, using a total amount of 14 units (1 patient required two procedures due to sepsis in the generator pouch). Most important intraoperative incidences have been defibrillation thresholds between 20-24 J in 4 cases, displacement of defibrillation electrode from vena cava into coronary sinus in 4 cases, epicardial patch implantation via subcostal approach in 1 case and right ventricle perforation in 1 case. No operative mortality was registered. One patient suffered sudden death during follow-up. Surgical complications were few: 1 case of lead dislodgement and 1 infected wound in the generator's pouch. Non-surgical complications were also few: 1 case with superior vena cava syndrome and 1 patient with inadequate discharges. In conclusion, due to our early experience, we believe that endocavitary implantation of an implantable cardioverter-defibrillator is the procedure of choice at the present time.

Adult↗