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Biomedical subjects

M J Porter

Publications and source records attributed to M J Porter.

32 records · Page 2Linked to original sources
PubMed1991

Comparison of cocaine alone or with adrenaline on nasal mucosal blood flow.

Cocaine is commonly used in ENT practice for its vasoconstrictor and anaesthetic properties. It is sometimes combined with adrenaline. The laser Doppler Flowmeter was used to compare the effect of 5 per cent cocaine alone or with adrenaline (1 in 1,000) on nasal mucosal blood flow. The results show an average fall in blood flow of 76.7 per cent for cocaine with adrenaline, compared to 61.2 per cent with cocaine alone. The difference is significant (P less than 0.05). The time taken for the blood flow to fall was an average of 131 s and 160 s respectively. These differences are not significant.

Adult↗
PubMed1991

False ankylosis of the temporomandibular joint after otologic and neurotologic surgery.

Two cases of ankylosis of the temporomandibular joint (TM) after otologic and neurotologic surgery involving an approach through the temporal fossa are reported. The etiology is believed to be that of fibrous contracture within the temporalis muscle, which is incised during the procedure. If the possibility of this rare complication is anticipated, the immediate instigation of prophylactic jaw exercises and forced opening with tongue depressors can significantly limit morbidity. If the condition is allowed to become established, then surgical correction by coronoidectomy may be necessary.

Adult↗
PubMed1989

Enhancing the image of nursing.

A Task Force from a Midwestern teaching hospital developed a comprehensive strategy to enhance the image of nursing in both the hospital and the community. Nursing administrators will find the Task Force's process and outcomes useful in addressing the image of nursing in their own institutions.

Career Choice↗
PubMed1984

Pediatric skin disease in Pakistan. A study of three Punjab villages.

The population of children younger than 5 years old in three widely distributed villages in Punjab, Pakistan, was examined for skin disease in November 1980. Approximately 29% of the children had infectious skin disease, with pyoderma the predominant diagnostic category. There were significant differences in pyoderma prevalence rates between villages, with the suppressive effect of malathion spraying for malaria control on the insect population representing the most likely explanation for the observed differences. These data again emphasize the amount of skin disease, particularly in children, in rural areas of the lesser developed countries, and the desirability of focusing attention on the dermatologic needs of this vast sector of the world's population.

Age Factors↗
PubMed1980

Seasonal change and its effect on the prevalence of infectious skin disease in a Gambian village.

A longitudinal dermatological study was carried out to determine the effect of seasonal change on the prevalence of skin diseases, particularly infectious skin diseases. This study was performed at the end of the rainy season and at the end of the subsequent dry season at Keneba, The Gambia. The surveys provide a profile of the influence of climate on the prevalence of certain skin diseases, both in terms of the susceptible diseases and who in the community was most affected. These surveys also provided an appreciation of the magnitude of skin disease in the community. The greatest effect of climatic change was on the prevalence of the dermatomycoses and pyoderma in children under 10. No seasonal influences were detected with other forms of skin disease. Some unusual aspects of scabies were noted in the surveys, particularly the low prevalence and the unusual age distribution pattern with no higher prevalence amongst children.

Child↗
PubMedDate not supplied

Career development: our professional responsibility.

Literature indicates that nurses' contributions to the health care profession are misunderstood by the general public. Of equal importance is how nurses perceive themselves. The present study attempted to describe the self-image of nurses working in a hospital setting and to determine whether there are differences in self-image between beginning and expert nurses, between caregivers and noncaregivers, between nurses with different levels of education, and between full-time and part-time nurses. Using the Porter Nursing Image Scale, a sample of 363 nurses perceived themselves positively on the three factors: Interpersonal Power, Interpersonal Relations, and Intrapersonal Ability. Significant differences were found between beginning and expert nurses, between caregivers and noncaregivers, between those with BSN and MSN education, and between full-time and part-time nurses. The data suggest the importance of graduate-level education for nurses and the need for career advancement and career counseling.

Adult↗
PubMedDate not supplied

Audit in the management of T3 fixed-cord laryngeal cancer.

PURPOSE: To determine results of various treatments for T3 fixed-cord lesions and the subset T3 glottic cancer in Auckland from 1979 to 1995. PATIENTS AND METHODS: Data were collected retrospectively from a departmental database, and the notes were reviewed. Because of the difficulty in determining the subsite of some fixed-cord lesions, the entire group of T3 fixed-cord lesions was examined, and those tumors that were considered to be definitely arising from the glottis were then analyzed as a specific subset. RESULTS: Fixed-cord lesions were diagnosed in 75 patients (21 supraglottic, 54 glottic). Primary surgery (total laryngectomy) was performed on 46 patients, primary radical dose radiotherapy was undertaken on 25 patients, and four patients were treated palliatively. For T3 fixed-cord lesions, disease-specific survival for radiotherapy and surgery was 36% and 66%, respectively, and 32% and 67%, respectively, for T3 glottic lesions. For both T3 fixed-cord and T3 glottic lesions, surgery produced significantly better survival than did radiotherapy (<60 Gy; P = .0157). With radiotherapy greater than 60 Gy, cancer of the larynx has been controlled in seven of 13 patients, although only five patients are alive, with a median follow-up of 24 months (range, 12-49 months). CONCLUSION: Radiotherapy less than 60 Gy produced markedly inferior results to surgery for T3 fixed-cord lesions and T3 glottis in Auckland. Radiotherapy at more than 60 Gy shows promise, but an ongoing audit is essential to ensure that survival is similar to surgery and to that reported by those promoting organ-preservation protocols.

Carcinoma, Squamous Cell↗
PubMedDate not supplied

Detection of the tumour suppressor gene p53 in nasopharyngeal carcinoma in Hong Kong Chinese.

This study has investigated the expression of the p53 tumour suppressor gene in 41 cases of primary nasopharyngeal carcinomas (NPC) using the p53 monoclonal antibody BP53-12. Moderate p53 expression was found in 54% and strong expression in 12% of the specimens. There was no correlation between p53 expression and any of the clinicopathological parameters or survival. Surprisingly, three research groups have investigated p53 mutations in NPC and found no fresh tumour specimens to contain p53 mutations in exons 4-8 of the gene. It may be argued that as p53 overexpression has been demonstrated in 70% of the patients investigated in this study, that the mutations lie outside the 4-9 exon region. We are in the process of testing this hypothesis.

Adult↗