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M J McCarthy

Publications and source records attributed to M J McCarthy.

At least 55 records · Page 3Linked to original sources
PubMed1995

The Processes, Structures, and Outcomes of Care in Cardiac Surgery study protocol.

Recently, a growing interest has arisen in defining and measuring health care outcomes. Although outcome measures may be used as potential quality-of-care screens, outcomes cannot indicate directly how care might be improved. Thus, the Processes, Structures, and Outcomes of Care in Cardiac Surgery (PSOCS) study was designed to investigate the linkages between the processes and structures of care with risk-adjusted outcomes for cardiac surgery care. Data are being collected on a comprehensive array of risk factors, processes, structures, and outcomes of care at 14 Veterans Affairs Medical Centers for this prospective, observational study. Approximately 6,000 cardiac surgery patients will be enrolled in this study over a 4.5-year period. Patient selection is based on a 6 workday rotating sampling frame with an oversampling of emergent patients. During the study, a register of all patients undergoing cardiac surgery at these centers is being maintained to assess the overall context of patient recruitment. The study will continue to enroll patients through December 1996. Major study end points extend beyond traditional measures of 30-day mortality and morbidity to encompass more innovative intermediate outcome measures, including changes in physical functional status and health-related quality of life.

Aged↗
PubMed1995

Evaluating anesthesia health care delivery for cardiac surgery. The role of process and structure variables.

Anesthesia care is an integral component of cardiac surgery. Emphasis on cost-effectiveness and decreased hospital stay has prompted reevaluation of anesthesia practice. However, the role of anesthesia process and structure variables in relation to patient outcomes is largely unknown. Processes, Structures and Outcomes of Care in Cardiac Surgery is the first epidemiologic study to collect data on anesthesia processes, such as the pharmacologic components of anesthesia and types of cardiovascular monitors used. Structures of care, such as resident staffing, supervision, completeness of documentation, and training and experience of care providers, are also being assessed. Pilot data collected from September 1992 to September 1993 demonstrate substantial variation between the six study sites in selected processes and structures. Despite the near-universal use of narcotic anesthesia as the primary anesthetic technique, variation in the type of opioid and adjuvant benzodiazepine used was observed. Regarding invasive hemodynamic monitoring, most centers used only one type of catheter. Intraoperative transesophageal echocardiography was used commonly at several centers for valve surgery, whereas other centers did not use it at all. Its use during coronary artery bypass grafting was less common. Assessment of the preoperative anesthesia note revealed that coronary anatomy and ventricular function were noted in nearly all instances. However, a clear notation that risks and benefits of anesthesia were discussed was less frequent. Structures related to anesthesia attending staffing, board certification, and experience revealed variation. Some sites had smaller and/or more experienced attending staffs, whereas others had larger and/or less experienced staffs. These pilot findings appear to validate the authors' hypotheses that variations in anesthesia practice are present within the Veterans Affairs system. They suggest that the variable set is robust enough to relate processes and structures of anesthesia care to patient outcome.

Anesthesiology↗
PubMed1995

Self-report measures for assessing treatment outcomes in cardiac surgery patients.

Patient self-report measures are increasingly valued as outcome variables in health services research studies. In this article, the authors describe the Functional Status, Health Related Quality of Life, Life Satisfaction, and Patient Satisfaction scales included in the Processes, Structures, and Outcomes of Cardiac Surgery (PSOCS) cooperative study underway within the Department of Veterans Affairs health care system. In addition to reporting on the baseline psychometric characteristics of these instruments, the authors compared preoperative Medical Outcomes Study SF-36 data from the study patients with survey data from a probability sample of the US population and with preoperative data on cardiac surgery patients from a high volume private sector surgical practice. Descriptive analyses indicate that the SF-36 profiles for all of the cardiac patients are highly similar. The Veterans Affairs and private sector patients report diminished physical functioning, physical role functioning, and emotional role functioning as well as reduced energy relative to an age-matched comparison sample. At the same time, however, the Veterans Affairs patients evidenced lower levels of capacity on most of the SF-36 dimensions relative to the private sector patients.

Cardiac Surgical Procedures↗
PubMed1994

Turbulent pipe flow studied by time-averaged NMR imaging: measurements of velocity profile and turbulent intensity.

A time-averaged method to obtain quantitative measurements in turbulent flow by phase flow encoding NMR imaging is introduced. With this method time-averaged velocity profiles and turbulence intensities can be determined. Time-averaged velocity profiles for pipe flow of water driven by a constant pressure gradient at Reynolds numbers from 1200 to 9400 were visualized. A precise correlation between the pixel intensity of the time-averaged NMR flow image and the local turbulence intensity of the flow is derived. The measured turbulence intensities are in agreement with published data obtained using other experimental methods.

Magnetic Resonance Spectroscopy↗
PubMed1994

Get off the bill hook.

In an increasingly strict financial climate increasing income is just as important as reducing costs, and so is increasing the speed at which income is collected. Tom Jones, of health care management consultants, McLean Jones McCarthy, provides some tips on how managers can deal with debtors, manage an efficient finance directorate--and get off the bill hook.

Accounts Payable and Receivable↗
PubMed1991

Phase volume measurements using magnetic resonance imaging.

The phase distribution of components in both model and actual food systems has been quantified using Magnetic Resonance Imaging. We present measurements of effective moisture diffusivities, vertical mass distributions in foams, and crystallization of water and lipid components. The interpretation of this information allows one to quantify the interactions of various components and structural features within a sample. These measurements are made noninvasively and nondestructively and can be repeated over time to obtain information on the dynamics of the system.

Chemical Phenomena↗
PubMed1989

Localized benign and malignant fibrous tumors of the pleura. A clinicopathologic review of 223 cases.

We reviewed 223 localized fibrous tumors of the pleura and divided them histologically into 141 benign and 82 malignant neoplasms. The criteria used for a judgement of malignancy were high cellularity and mitotic activity (more than four mitotic figures per 10 high-power fields), pleomorphism, hemorrhage, and necrosis. The tumors occurred equally in both sexes, most commonly in the sixth to seventh decades of life. Presenting symptoms included chest pain, dyspnea, and cough; they were observed in three-fourths of patients with a malignant tumor. One in every four of these patients had hypoglycemia, clubbed digits, or pleural effusion. Two-thirds of the tumors were attached to visceral pleura, often by a pedicle. The rest arose from the parietal pleura of the chest wall, diaphragm, or mediastinum. Neoplasms in these atypical sites, together with fissural lesions and tumors "inverted" into peripheral lung, were more often malignant. Most neoplasms measured 5-10 cm and weighed 100-400 g. Microscopically, the "patternless pattern," or hemangiopericytic type, was seen in the majority of cases, and mixed patterns were seen in nearly 40% of tumors. Of the 169 tumors where follow-up was available, all of the benign and 45% of the malignant tumors were cured by simple excision. Patients surgically cured of a malignant neoplasm had pedunculated or well-circumscribed lesions. However, 55% of patients with malignant tumors succumbed to their disease secondary to invasion, recurrence, or metastasis. Resectability is the single most important indicator of clinical outcome. No tumor expressed epithelial differentiation, either immunohistochemically or ultrastructurally; therefore, we favor the term "localized fibrous tumor" of pleura instead of "localized mesothelioma."

Adolescent↗
PubMed1988

Radiologic evaluation of mass casualty victims: lessons from the Gander, Newfoundland, accident.

This study describes the use of radiologic methods in the identification of 256 bodies after the crash of an airliner in Gander, Newfoundland. Two hundred thirty-one (90%) of the victims were identified positively with dental and/or fingerprint comparisons. Radiologic data confirmed identification in 29 of these victims. Seventeen bodies without dental or fingerprint identification were presumptively identified with a variety of data, which included radiologic characteristics in four cases. Eight bodies were identified with an exclusion matrix. Radiologic input was critical in two of these. The procedures described provide practical information for radiologists in a mass casualty disaster investigation.

Accidents, Aviation↗
PubMed1987

Tumors of the small intestine with little or no malignant predisposition: a review of the literature and report of 56 cases.

Benign small bowel tumors are rare. If those with malignant potential are excluded, a small group of truly benign lesions remains. Fifty-six cases of these small bowel tumors were analyzed for clinical data, pathologic diagnosis, number, size, location, and radiologic appearance. Lesions included lipoma, myoepithelial hamartoma, Peutz-Jeghers hamartoma, neurogenic tumors (including gangliocytic paraganglioma), Brunner's gland abnormalities, and inflammatory fibroid polyp. Location, number, and radiographic morphology can be helpful in reaching a more specific diagnosis. Age of patient and size of tumor may be helpful in the differential diagnosis; however, sex of the patient and clinical symptoms are not.

Adenoma↗
PubMed1987

Gastrointestinal teratomas: CT and US appearance with pathologic correlation.

Gastrointestinal teratomas are uncommon, benign neoplasms that occur primarily in children. A retrospective review of five cases (two gastric, one pancreatic, one mesenteric, and one in the lesser omentum) is presented with emphasis on the computed tomographic and ultrasonographic appearances. Principal findings are a well-defined mass with separate cystic and solid components of varying proportions, discrete areas with densities similar to that of fat, or coarse, globular calcifications within the solid component. Recognition of these findings may allow the radiologist to make a correct preoperative diagnosis of teratoma.

Child, Preschool↗
PubMed1986

Concepts in computed tomography of the thorax.

A number of concepts in the CT evaluation of the thorax have been reviewed. The concepts have been presented through anatomic images generated on a specific CT system, but any equivalent system could have produced similar images. The important conclusions derived as a result of this review are: 1. Slice thickness, volume averaging and volume sampling are interrelated. Slice thickness and the orientation and inherent subject contrast of the anatomy to be studied usually determine the quality of the image obtained. 2. Thin section imaging (i.e., 5 mm and especially 1.5 mm) can demonstrate thoracic anatomy rarely (if ever) observed on thicker images (i.e., 10 mm). Although impractical for general analysis, thin section imaging provides insight into the potential limitations of a standard approach to thoracic evaluation. 3. CT analysis of the normal anatomy of the pericardium is incomplete. Although pathology related to the pericardium has been presented in the literature, more work is required to define: 1, the relationship, on CT, of the pericardium to structures within its confines; 2, abnormalities within the mediastinum that may affect the pericardium, and 3, lesions in the lung that may invade the mediastinum and pericardium. 4. The excellent contrast sensitivity of CT (aided by iodine infusion or bolus injection techniques and dynamic scanning) does not suffice to resolve certain problems in thoracic analysis. Extrapleural signs, the concept of invasion versus abutment, and the discrimination of benign from malignant mediastinal nodes continue to present diagnostic dilemmas in CT analysis of the thorax. 5. Interesting cases provide models for demonstrating CT pitfalls, mimics, and rarities. CT can be a valuable tool in resolving diagnostic dilemmas in some cases but creates dilemmas in others. 6. CT reformation images of the thorax can be dynamically generated on the scanner console. This hands-on technique can be a valuable tool for teaching anatomy in resident training programs.

Adult↗
PubMed1985

Pulmonary nodules: detection of calcification by linear and pluridirectional movement in tomographic study.

Calcification within solitary pulmonary nodules (1-2 cm range) was demonstrated by conventional tomography in a group of 20 patients. Each patient had a combined tomographic examination consisting of 15 degrees linear movement followed by 34 degrees hypocycloidal movement. Linear tomography was superior to pluridirectional tomography in 19 cases for visualization of calcium within the nodule. The results are attributed to differences in contrast sensitivity and "blur" phenomena between the two tomographic movements. This study, although comparing a specific linear movement with a specific pluridirectional movement, provides insight into the differences between tomographic techniques for a given task.

Adolescent↗
PubMed1983

The effect of lithium on renal haemodynamic function.

Renal concentrating capacity following 18 hours of fluid deprivation was measured in 75 patients receiving prophylactic lithium therapy, and in 30 affectively ill subjects receiving other drugs. The lithium-treated patients had significantly lower urine osmolality and higher serum osmolality than the control subjects. Older subjects, patients maintained at higher serum lithium levels and those with a history of previous neurotoxicity showed the most impairment. Ten patients with urine osmolalities of less than 700 mOsm/1 following this test were investigated further. Inulin and para-amino hippurate (PAH) clearance rates were determined and the effect of a subpressor challenge of dopamine on these measures was observed. Half of the patients showed some reduction in inulin and PAH clearance, which was greatest in those patients who had been taking lithium for over 10 years. However, all of the patients tested showed the expected increase in renal blood flow and sodium and water excretion in response to dopamine. Six additional patients had clearance estimations made before starting lithium treatment which were repeated after a period of 3-6 months on the drug. No consistent changes in haemodynamics were observed. Lithium clearly reduces renal concentrating capacity, but other measures of renal tubular function were well preserved in patients receiving long-term therapy. Glomerular function may be slightly reduced in patients taking lithium for long periods. The results show that prophylactic lithium treatment does not affect renal cortical function adversely in the majority of patients, but impaired renal concentrating ability is a common accompaniment.

Adult↗
PubMed1982

Hydroa vacciniforme: diagnosis and therapy.

Hydroa vacciniforme is a rare, chronic photodermatosis with onset in childhood. Multiple exposures to UV-A reproduced the symptoms and the vesicular and scarring lesions typical of the sun-induced disease in our patient. Treatment with hydroxychloroquine sulfate, but not indomethacin, reduced the photosensitivity both to sunlight and to artificial UV-A light. Serum complement levels were low while the disease was active and returned to normal after treatment of the patient with hydroxychloroquine.

Adolescent↗