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M J Gibney

Publications and source records attributed to M J Gibney.

At least 37 records · Page 2Linked to original sources
PubMed2003

Validation analysis of probabilistic models of dietary exposure to food additives.

The validity of a range of simple conceptual models designed specifically for the estimation of food additive intakes using probabilistic analysis was assessed. Modelled intake estimates that fell below traditional conservative point estimates of intake and above 'true' additive intakes (calculated from a reference database at brand level) were considered to be in a valid region. Models were developed for 10 food additives by combining food intake data, the probability of an additive being present in a food group and additive concentration data. Food intake and additive concentration data were entered as raw data or as a lognormal distribution, and the probability of an additive being present was entered based on the per cent brands or the per cent eating occasions within a food group that contained an additive. Since the three model components assumed two possible modes of input, the validity of eight (2(3)) model combinations was assessed. All model inputs were derived from the reference database. An iterative approach was employed in which the validity of individual model components was assessed first, followed by validation of full conceptual models. While the distribution of intake estimates from models fell below conservative intakes, which assume that the additive is present at maximum permitted levels (MPLs) in all foods in which it is permitted, intake estimates were not consistently above 'true' intakes. These analyses indicate the need for more complex models for the estimation of food additive intakes using probabilistic analysis. Such models should incorporate information on market share and/or brand loyalty.

Databases, Factual↗
PubMed2003

Assessment of food intake input distributions for use in probabilistic exposure assessments of food additives.

A key component of a food chemical exposure assessment using probabilistic analysis is the selection of the most appropriate input distribution to represent exposure variables. The study explored the type of parametric distribution that could be used to model variability in food consumption data likely to be included in a probabilistic exposure assessment of food additives. The goodness-of-fit of a range of continuous distributions to observed data of 22 food categories expressed as average daily intakes among consumers from the North-South Ireland Food Consumption Survey was assessed using the BestFit distribution fitting program. The lognormal distribution was most commonly accepted as a plausible parametric distribution to represent food consumption data when food intakes were expressed as absolute intakes (16/22 foods) and as intakes per kg body weight (18/22 foods). Results from goodness-of-fit tests were accompanied by lognormal probability plots for a number of food categories. The influence on food additive intake of using a lognormal distribution to model food consumption input data was assessed by comparing modelled intake estimates with observed intakes. Results from the present study advise some level of caution about the use of a lognormal distribution as a mode of input for food consumption data in probabilistic food additive exposure assessments and the results highlight the need for further research in this area.

Eating↗
PubMed2002

Overweight, obesity and physical activity levels in Irish adults: evidence from the North/South Ireland food consumption survey.

In the present paper the prevalence of obesity (BMI > or = 30 kg/m2) and current physical activity levels in Irish adults have been evaluated. The prevalence of obesity in Irish adults is currently 18%, with men at 20% and women at 16%. A further 47% of men and 33% of women are overweight (BMI 25.0-29.9 kg/m2). Since 1990, obesity has more than doubled in men from 8% to 20%, and increased from 13% to 16% in women. The highest prevalence of obesity (30%) was found in women aged 51-64years. Defined waist circumference action levels identified 48% of the population who are in need of weight management and who also are at a 1.5-4.5 times increased risk of having at least one cardiovascular disease risk factor. Physical activity levels were low overall. Men were more active in work and recreational pursuits than women, but women were more active in household activities. Walking was the most popular recreational pursuit. However, TV viewing occupied most of the leisure time of men and women. Higher levels of activity were associated with a lower BMI and waist circumference. The results indicate the need for sensitive and individualised strategies to promote physical activity and to achieve a healthy weight status.

Adolescent↗
PubMed2002

Irish National Food Ingredient Database: application for assessing patterns of additive usage in foods.

Patterns of food additive usage in the Irish food supply and changes in patterns of usage between 1995-97 and 1998-99 were assessed by means of an Irish National Food Ingredient Database (INFID). Of the 300 additives permitted for use according to the European Union food additives Directives, some 54% were recorded in foods in INFID. Colours, emulsifiers and acids were the most frequently used additive categories, representing 18, 13 and 12% of the total additives used, respectively. Colours were most commonly recorded in sauces (n = 182 brands, 26% of sauces), emulsifiers were most commonly recorded in biscuits (n = 181 brands, 47% of biscuits) and acids were most commonly recorded in sauces (304 brands, 43% of sauces). Carotenes (E160a), Annatto (E160b), mono- and diglycerides of fatty acids (E471) and citric acid (E330) were the most commonly used colour, emulsifier and acid, respectively. All diet soft drinks (n = 37), low-fat spreads (n = 25) and liver pâtés (n = 10) recorded the use of at least one additive. When expressed in terms of the number of brands that contain additives, sauces (n = 522, 73% of sauces), biscuits (n = 323, 84% of biscuits) and preserves (n = 321, 85% of preserves) were ranked highest. For most categories of additive (n = 24), there appeared to be a minimal change in qualitative additive usage between 1995-97 and 1998-99. However, there was a significant increase in the frequency of use of emulsifiers (p < 0.001), acids (p < 0.01), sweeteners (p < 0.05) and acidity regulators (p < 0.05), and a significant decrease in the frequency of use of antioxidants (p < 0.05) during the period 1998-99 compared with 1995-97. Despite changes in additive usage patterns, it appeared that changes in the types of brands on sale between both periods were more apparent than actual changes in qualitative ingredient formulations across brands, as some 17% of brands that were on sale in 1995-97 were no longer on sale in 1998-99.

Databases, Factual↗
PubMed2001

Perception of body image as indicator of weight status in the European union.

OBJECTIVE: To identify the factors associated with an adequate perception of body image in relation to body weight. MATERIAL AND METHODS: An observational, cross-sectional study was conducted in a representative sample of the European Union (7,155 men and 8,077 women). Body Mass Index (BMI) was grouped into four categories, perceived body image was assessed using the nine silhouettes drawing scheme. A multivariable logistic regression model for each sex was used to adjust for potentially confounding variables. RESULTS: Underweight men and women classified themselves better than other groups (92.9% of correct answers among men and 79.3% among women). Overall, women classified themselves better than men (57.6% vs. 32.7%). DISCUSSION: Perceived body image as a method of assessment for body weight has different validity depending on sociodemographic or attitudinal categories. Perceived body image as an estimate of the nutritional status has a limited individualized application. Thus, perhaps it could be applied as a proxy measure of adiposity among slim males and among slim and overweight females, but not among the other groups.

Adolescent↗
PubMed2001

Eating patterns--temporal distribution, converging and diverging foods, meals eaten inside and outside of the home--implications for developing FBDG.

OBJECTIVE: A consideration of eating patterns in the general population is necessary when deriving food-based dietary guidelines (FBDG) as promoting the intake of one food may indirectly result in the increased consumption of another, which may not always be desirable. A number of issues that influence meal patterns such as temporal distribution of food intake (using data from the Netherlands), converging and diverging foods (using data from Ireland) and meals eaten inside and outside of the home (using data from the UK) are examined and discussed in the context of developing FBDG. SETTING: Food intake databases from three EU countries: The Netherlands, Ireland and the UK. RESULTS: The hot meal (dinner) was found to be the main contributor to the intake of energy and macro-nutrients in the Dutch population. It was also the main contributor to the intake of all micro-nutrients with the exception of calcium where the bread meal contributed a similar proportion as the hot meal to the intake of this micronutrient. Furthermore, fruit intake showed a very different temporal distribution to vegetable intake. Exploring the convergence of certain foods in the Irish population also revealed differences between fruit and vegetables. A low correlation was shown for consumers of fruit and vegetables indicating that being a high fruit consumer did not suggest being also a high vegetable consumer. An examination of where meals were consumed among British adults showed that 71% of all meals were consumed inside the home while 29% were consumed outside. 27% of food energy and 45% of alcohol energy was consumed out of home by the total population. In addition, those eating less of their foods out of home obtained a lower proportion of their food energy from fat and protein and a higher proportion from carbohydrate. A different demographic profile was associated with eating out compared to eating in, comprising more males and younger individuals. CONCLUSIONS: Information on patterns of food intake and food habits, specifically temporal distribution, the convergence and divergence of foods and foods consumed inside and outside of the home, give a culturally specific picture of food consumption practices within a population. This should enable the development of more culturally acceptable and realistic FBDG.

Adolescent↗
PubMed2001

The North/South Ireland Food Consumption Survey: survey design and methodology.

OBJECTIVE: The purpose of this survey was to establish a database of habitual food and drink consumption in a representative sample of Irish adults aged 18-64 years. DESIGN: A cross-sectional food consumption survey was carried out. Food intake data were collected using a 7-day estimated food diary. Anthropometric data included measurements of weight, height, waist and hip circumferences and body composition using bioelectrical impedance analysis. Questionnaire data included assessments of health, lifestyle and socio-demographic status, levels of physical activity, attitudes to diet and health and restrained eating. SETTING: Northern Ireland and Republic of Ireland between 1997 and 1999. RESULTS: In total, 1379 adults aged 18-64 years participated in the survey and completed the 7-day food diary. This paper gives details of the methods used to carry out the survey. Sampling, respondent recruitment, dietary assessment, collection of anthropometric and questionnaire data and data management and analysis are described. CONCLUSION: The North/South Ireland Food Consumption Survey is unique in being the first food consumption survey ever to be carried out in the Republic of Ireland and Northern Ireland concurrently using the same methodology.

Adolescent↗
PubMed2001

An evaluation of energy intakes and the ratio of energy intake to estimated basal metabolic rate (EI/BMRest) in the North/South Ireland Food Consumption Survey.

OBJECTIVE: To examine energy intakes (EI), their ratio to estimated basal metabolic rate (BMR(est) and the contribution of food groups to energy intake in the North/South Ireland Food Consumption Survey. DESIGN AND SETTING: Random sample of adults from the populations of Northern Ireland and the Republic of Ireland. Food intake data were collected using a 7-day food diary. Body weight and height were measured and EI/BMR(est) was calculated from reported energy intake and estimated basal metabolic rate. Dieting practices were assessed as part of a self-administered questionnaire. RESULTS: Mean energy intake in men was 11.0 MJ and in women was 7.6 MJ, which is comparable to reported energy intakes in Northern Ireland and the Republic of Ireland over a decade ago. Mean EI/BMR(est) was 1.38. This increased to 1.42 after the exclusion of dieters and those who were unwell, but still remained less than the established cut-off of 1.53. EI/BMR(est) was significantly (P<0.05) higher in men than in women and decreased significantly (P<0.05) with increasing BMI in both sexes. The four food groups that contributed 50% of energy in men and women were meat and meat products, breads and rolls, potatoes and potato products, and biscuits, cakes, pastries and puddings. CONCLUSIONS: Energy intakes have not changed remarkably in Northern Ireland or the Republic of Ireland in the last 10 years, but the mean EI/BMR(est) of 1.38 suggests that energy underreporting occurred. EI/BMR(est) was lower in women and in the overweight/obese. Additional multivariate analysis of the data is needed to identify more clearly subgroups of the population reporting lower than expected energy intakes and to evaluate the effect of low energy reporting on the consumption of various foods and food groups.

Adolescent↗
PubMed2001

Macronutrient intakes and food sources in Irish adults: findings of the North/South Ireland Food Consumption Survey.

OBJECTIVE: To describe macronutrient intakes and food sources of the adult population in the Republic of Ireland and Northern Ireland and to assess adherence of this population to current dietary recommendations. DESIGN: A cross-sectional food consumption survey collected food intake data using a 7-day food diary. SETTING: Northern Ireland and the Republic of Ireland between October 1997 and October 1999. SUBJECTS: One thousand three hundred and seventy-nine adults aged 18-64 years (662 males and 717 females). RESULTS: Mean daily energy intakes in men were 11 MJ per day, 15.5% was derived from protein, 34.8% from fat, 43.5% from carbohydrate and 5.9% from alcohol. Corresponding figures for women were 7.6 MJ per day, 15.6%, 35.6%, 45.1% and 3.5%. When alcohol energy was excluded the contribution of fat and carbohydrate to energy did not differ between men and women. When compared with existing dietary recommendations, 93% of men and 86% of women had protein intakes above the Population Reference Intake. Two approaches were used to assess adherence to the fat and carbohydrate dietary recommendations: (1) the proportion of individuals in the population attaining these dietary targets and (2) the proportion of the population that was included in a 'compliers' group which had a group mean equal to these dietary targets. Thirty-three per cent of men and 34% of women met the target of 35% of food energy from fat and 78% of men and 80% of women comprised the 'compliers' group having a group mean of 35% of food energy from fat. Twenty-three per cent of men and 27% of women met the target of 50% of food energy from carbohydrate and 56% of men and 62% of women made up the 'compliers' group. Meat and meat products were the main source of fat (23%) and protein (37%), and bread and rolls (25%) were the main source of carbohydrate. CONCLUSION: A reduction in dietary fat intake remains an important public health issue in the Republic of Ireland and Northern Ireland. An increase in carbohydrate intake and attention to the rise in alcohol intake is also warranted.

Adolescent↗
PubMed2001

Analyses of the anthropometric data from the North/South Ireland Food Consumption Survey.

OBJECTIVE: To obtain measured anthropometric data for weight, height and other parameters not previously measured in the Irish population such as waist and hip circumferences and body composition. DESIGN: A cross-sectional survey. Weight, height, waist circumference, hip circumference and body composition were measured according to standard procedures. SETTING: Northern Ireland and the Republic of Ireland, 1997-1999. SUBJECTS: Random representative sample of 1379 adults aged 18-64 years. RESULTS: With the exception of body fat, all anthropometric values were significantly higher for men than women (P<0.001). All measurements were significantly higher in the 36-50-year-old age group compared with 18-35 year olds. Height was the exception, which decreased significantly with age (P<0.05). Weight, height and body mass index (BMI) have increased in Ireland since last measured in 1988 and in 1990. Over the last decade, obesity has increased in men 2.5 fold from 8% to 20% and in women by 1.25 fold from 13% to 16%. Significantly more women have a normal BMI than men (50.4% vs. 33.3%; P<0.05). Cut-off points for a high waist circumference and high waist-to-hip ratio identified 47% and 33% of the population, respectively, to be at an increased risk for cardiovascular disease. Social class did not have any significant effect on mean BMI. Location of residence influenced BMI but not in any consistent manner. Ex-smokers had a significantly higher BMI than non-smokers and smokers (P<0.05). CONCLUSIONS: A revision of current recommendations for combating obesity is warranted to improve the health of the Irish population. Further research is needed to identify the factors that have contributed to the dramatic increase in the prevalence of obesity in men over the last decade and have resulted in a higher prevalence of obesity in men than in women.

Adipose Tissue↗
PubMed2001

Attitudes towards and beliefs about nutrition and health among a random sample of adults in the Republic of Ireland and Northern Ireland.

OBJECTIVES: For effective healthy eating promotion, it is necessary to understand the attitudes towards and beliefs about nutrition of the general public. The objective of this study was to provide data on attitudes towards eating a healthy diet and the perceived need to alter eating habits from a random sample of adults in the Republic of Ireland and in Northern Ireland, using a self-administered questionnaire. DESIGN: Cross-sectional survey using a self-administered attitudinal questionnaire on beliefs and attitudes to healthy eating. SETTING: The survey was carried out between October 1997 and October 1999 in the Republic of Ireland and in Northern Ireland. SUBJECTS: A randomly selected sample of 1256 adults from the Republic of Ireland and Northern Ireland completed the attitudinal questionnaire. RESULTS: A majority of subjects (62%) perceived that they make conscious efforts to eat a healthy diet either most of the time or quite often, while just over half (52%) agreed that they do not need to make changes to their diet as it is healthy enough. Subjects most likely to make conscious efforts to try to eat a healthy diet were females, older subjects (51-64 years) and those with the highest intakes of fruit and vegetables and lowest quartile of fat (% food energy). When self-assessed adequacy of fruit and vegetables was examined, two-thirds of the total sample felt they ate too little fruit while just one-third felt they ate too little vegetables. CONCLUSION: Results of the present study, in general, revealed good agreement between attitude and behaviour with respect to healthy eating. This suggests that people appear to be reasonably accurate at evaluating their own diet in terms of how healthy it is. In terms of the two food groups examined in this study, some optimistic bias was evident for vegetables but not for fruit. It may be useful therefore to assess attitudes and beliefs about healthy eating by way of examining attitudes to such food groups individually.

Adolescent↗
PubMed2001

Fatty acids and epithelial permeability: effect of conjugated linoleic acid in Caco-2 cells.

Conjugated linoleic acid (CLA) is a collective term referring to the positional and geometric isomers of linoleic acid. This novel fatty acid has been shown to have a number of beneficial actions, including immunomodulatory, anticarcinogenic, and antiatherogenic effects. Tight junctions of epithelial cells determine epithelial membrane integrity and selective paracellular permeability to ions and macromolecules. Occludin and ZO-1 are integral structural components of the tight junction, which are involved in the biogenesis and functional integrity of the epithelial monolayer. This study investigated the effects of two isomers of CLA (cis-9 and trans-10 isomers) on Caco-2 cell transepithelial resistance (TER) development, paracellular epithelial permeability, and occludin and ZO-1 expression. Caco-2 cells were grown in media supplemented with 0.05 mM linoleic acid, cis-9 CLA, or trans-10 CLA for 21 days. The trans-10 CLA isomer delayed Caco-2 cell TER development, which is an in vitro measure of epithelial cell integrity, and increased paracellular epithelial permeability. Immunofluorescent staining of Caco-2 cell epithelial monolayers grown in media supplemented trans-10 CLA showed that the trans-10 CLA isomer altered distribution of occludin and ZO-1. The trans-10 CLA isomer delayed the acquisition of transepithelial resistance and altered the cellular distribution of occludin, which have important implications in relation to epithelial permeability.

Analysis of Variance↗
PubMed2001

Physical activity in European seniors: attitudes, beliefs and levels.

BACKGROUND: It is important to study the factors which modulate ageing, among which physical activity (PA) seems to have a very important role on the health status and quality of life of the elderly. To be effective, any intervention specifically targeted to promote PA should be based on the knowledge of the population, namely on their needs, attitudes and behaviour. OBJECTIVE: To identify in the elderly European population, the attitudes to PA and health, in order to define adequate strategies of promotion. DESIGN: Cross-sectional survey using a face-to-face interview-assisted questionnaire. This project belongs to the multicentric Pan-EU Survey on Consumer Attitudes to PA, Body Weight and Health under the leadership of the Institute of European Food Studies - Dublin with the cooperation of members from all European Union countries. 1914 European citizens, aged > or = 65, were interviewed. The data's descriptive analysis, was followed by univariate analysis to characterise the study's sample. RESULTS: PA was not viewed by the elderly as a major health determinant as it was ranked only 5th (18%), preceded by food (42%), smoking habits (40%) and alcohol (24%). 41% of elderly were not engaged in any type of PA, but 50% dedicated more than 3,5 hours/week on various activities. At EU level the most common activities included walking, gardening, cycling and swimming. 64% of the elderly thought that they do not need to do more PA, and 37% were in the pre-contemplation stage as they were currently not very physically active and they didn't intend to become physically active in the next 6 months. A large variation in attitudes, and behaviours in relation to PA, was found amongst European countries. CONCLUSION: Programmes to promote PA need to be tailored to the different countries in order to increase/maintain PA in the elderly.

Activities of Daily Living↗
PubMed2001

Healthy eating in European elderly: concepts, barriers and benefits.

BACKGROUND: The promotion of healthy eating is more likely to be effective if based on the understanding of how the elderly perceive their own diets and healthy eating. OBJECTIVES: The objectives of this study were to identify in the elderly European population, the attitudes to food, nutrition and health, in order to define adequate strategies of health promotion. DESIGN: Cross-sectional survey using a face-to-face interview-assisted questionnaire. This project belongs to the multicentric Pan-EU Survey on Consumer Attitudes to Food, Nutrition and Health under the leadership of the Institute of European Food Studies - Dublin with the cooperation of members from all EU countries. 1843 European citizens, aged > or = 65, were interviewed. The data's descriptive analysis, was followed by univariate analysis to characterise the study's sample according to the defined objectives. RESULTS: The most important factors influencing elderly's food choice were quality and freshness (54%), trying to eat healthy and price (8%). Healthy eating was defined as "less fat" (37%) "more fresh vegetables and fruit" (34%), and "natural foods" (11%). To stay healthy (36%), to prevent disease (26%) and to promote quality of life (10%) were the major benefits associated to healthy eating. However several barriers to the adoption of healthy eating were identified, namely self-control (27%), the resistance to change (23%) and price (15%). 86% of the elderly people believe they don't need to change their eating habits as they already eat healthily. CONCLUSION: Results of this study will help to improve eating habits in the elderly, as health professionals will be able to choose the most appropriate strategies for the different groups and settings, and provide a base for future interventions in European countries for this growing age group.

Aged↗
PubMed2000

The influence of survey duration on estimates of food intakes and its relevance for public health nutrition and food safety issues.

OBJECTIVE: To examine the influence of food consumption survey duration on estimates of percentage consumers, mean total population intakes and intakes among consumers only and to consider its relevance for public health nutrition and food safety issues. DESIGN: Prospective food consumption survey. SETTING: A multicentre study in five centres in the European Union-Dublin, Ghent, Helsinki, Potsdam and Rome. SUBJECTS: Teenage subjects were recruited through schools; 948 (80%) out of 1180 subjects completed the survey. INTERVENTIONS: 14-day food diaries were used to collect the food consumption data. RESULTS: For mean total population intakes, 53% of the foods had slopes significantly different to 0 (P<0.05). In practical terms (g/day), these differences were small, with 41% of foods having differences of </=1 g/day and a further 35% having differences of 1-5 g/day. Estimates of percentage consumers based on 3 days and 14 days were 1.9 and 3.6 times the 1-day estimate, respectively. For 72% of foods, at least 50% of non-consumers on day 1 became consumers over the subsequent 13 days. Estimates of mean consumer only intakes based on 3 days and 14 days were 53% and 32% of the 1 day value. CONCLUSION: In practical terms, survey duration influences estimates of percentage consumers and intakes among consumers only but not mean total population intakes. Awareness of this influence is important for improved interpretation of dietary data for epidemiological studies, development of food-based dietary guidelines and food chemical intakes. SPONSORSHIP: The Institute of European Food Studies, a non-profit research organization based in Trinity College Dublin. European Journal of Clinical Nutrition (2000) 54, 166-173

Adolescent↗
PubMed2000

Enhancing the capacity of food consumption surveys of short duration to estimate long-term consumer-only intakes by combination with a qualitative food frequency questionnaire.

In principle, a proper risk assessment for a food chemical requires that the time-frame for food chemical intake estimates matches the time-frame for the toxicological assessments upon which the safety statements (ADI, PTWI, etc.) are based. For food additives, the toxicological assessments are based on exposure over a lifetime. While food consumption data cannot be collected over the lifetimes of individuals, the information should reflect habitual intakes as closely as possible. This study investigated the possibility of combining a 3-day food diary with a food frequency questionnaire to estimate mean consumer-only food intakes comparable to estimates based on a 14-day diary. The study population consisted of 948 teenagers and analysis was based on 32 clearly defined foods. For 47% of the foods, the difference was < or = 1 g/day. When expressed as portion sizes, 56% of the foods showed differences representing < 5% of an average portion and no food showed a difference > 14% of an average portion. When between-method differences (portions/day) were plotted against the mean of the methods, the mean between-method difference was 0.02(+/- 0.06) portions/day with limits of agreement of -0.10 to 0.14. This preliminary investigation suggests that the combined 3-day diary and FFQ method provides comparable estimates of mean consumer only intakes to a 14-day diary. Therefore, a qualitative FFQ may be a useful adjunct to a food consumption survey of short duration if estimates of longer term food intakes are required.

Adolescent↗
PubMed2000

Differences in glucose-dependent insulinotrophic polypeptide hormone and hepatic lipase in subjects of southern and northern Europe: implications for postprandial lipemia.

BACKGROUND: This study was an extension of a previous study that showed different lipemic responses to standard test meals in subjects from southern and northern Europe. OBJECTIVE: The aim was to determine in 32 healthy young men from northern and southern Europe whether differences in the secretion of insulin and glucose-dependent insulinotrophic polypeptide (GIP) might explain these findings through the actions of these hormones on lipoprotein lipase. DESIGN: We investigated in a randomized, single-blind, crossover study the effects of 2 test meals of identical macronutrient composition but different saturated fatty acid (SFA) and monounsaturated fatty acid (MUFA) contents on postprandial GIP, insulin, the ratio of incremental triacylglycerol to apolipoprotein B-48 (a marker of chylomicron size), and the activity of postheparin lipases. RESULTS: Fasting and postprandial GIP concentrations and postheparin hepatic lipase activities were significantly higher in the southern Europeans (P < 0.001 and P < 0.02, respectively). Lipoprotein lipase activity after the SFA-rich meal was significantly higher in the northern Europeans (P < 0.01). HL activity 9 h after the SFA-rich meal and the area under the curve (AUC) for the postprandial insulin response correlated with the AUC for the postprandial GIP response [r = 0.44 (P < 0.04) and r = 0.46 (P < 0.05), respectively]. There were no significant differences in chylomicron size between the 2 groups for either meal, but when the groups were combined there was a significant difference in chylomicron size between the SFA- and MUFA-rich meals (P < 0.05), which could be due to the formation of larger chylomicrons after the MUFA-rich meal. CONCLUSION: The significantly higher GIP and insulin responses and HL activities in southern Europeans may provide an explanation for our previous report of attenuated postprandial triacylglycerol and apolipoprotein B-48 responses in them.

Adult↗