Biomedical subjects
M J Bennett
Publications and source records attributed to M J Bennett.
Inverted papilloma of the ureter.
Explore the source record for details and available documents.
Oxprenolol and the circulation during anaesthesia in the dog: influence of intrinsic sympathomimetic activity.
Oxprenolol is a non-selective adrenergic beta-receptor antagonist displaying beta-mimetic activity. To test the hypothesis that beta-mimetic activity could minimize the response of the circulation to adrenergic beta-receptor blockade, cumulative dose-response curves to oxprenolol 0.1-1.6 mg kg-1 were obtained in seven anaesthetized dogs. Anaesthesia was maintained with 0.5% halothane supplementing nitrous oxide 66% in oxygen, under moderately hypocapnic IPPV. Oxprenolol, up to 0.4 mg kg-1 i.v., caused modest increases in heart rate, LV dP/dt max and cardiac output. With the largest dose (1.6 mg kg-1), significant increases in heart rate (+19%), LV dP/dt max (+13%) and cardiac output (+27%) were observed while arterial pressure remained unchanged and systemic vascular resistance decreased (-18%).
Medicine in prospect--the first-year student's view.
A sample of first-year medical students from the University of New South Wales was interviewed to determine the students' reasons for studying Medicine, their career aspirations and their views, in prospect, of the medical course and medical practice. There were some differences, in general responses, between men and women. In general the interviews revealed that at this stage of their careers the students were motivated to a high degree by humanitarian concerns. Recent criticisms of the outcomes of medical education have featured concerns that graduating doctors do not demonstrate sufficient ability to relate to patients on a personal level or to take a holistic approach to care. Some medical educators and community spokesmen have attributed this to the selection system which, based solely on academic merit, chooses students with high academic ability and according to some critics, low social abilities and awareness. The results of this study indicate that such assumptions are false and that undesirable attitudes said to be present in graduating doctors do not appear to be present in the early stages of medical education.
Detection of intrauterine growth retardation by ultrasound: preliminary communication.
In this study, ultrasonic measurements of the fetal head area and abdominal area were obtained in 1200 patients with singleton pregnancies. The results from the 434 who have delivered, indicate that a large proportion of growth-retarded infants cannot be identified by a single late ultrasonic measurement of either area, at 32-34 weeks gestation, as has been previously suggested.
Prostaglandin vaginal suppositories: a simple and safe approach to the induction of labor.
The results of 1000 consecutive unselected cases of induction of labor for medical or obstetric reasons using prostaglandin E2 suppositories are presented. The overall rate of failed induction resulting in a cesarean section in those patients with an unfavorable cervix has fallen from 42 to 2.5%. Only 27% of the entire series required augmentation of labor with intravenous oxytocin, the range being from 9.9% of multigravidas with a favorable cervix to 42.4% of primigravidas with an unfavorable cervix. Both low- and high-risk pregnancies are suitable for induction by this method and trials of vaginal breech delivery and of uterine scars have been safely and successfully carried out. This method has now become routine for the induction of labor at the authors' institution. It has proved to be simple, safe, and highly acceptable to patients and obstetricians alike in all cases in which a simple amniotomy would not suffice.
Ocular dominance, eye alignment and visual acuity in kittens reared with an optically induced squint.
A horizontal concomitant strabismus produced optically in kittens with prisms caused a decrease in the proportion of binocularly excitable striate neurons with approximately equal percentages of neurons being driven by each eye. In addition, preventing fusion with prisms resulted in alterations in interocular alignment and in some cases a mild strabismic amblyopia. The changes in ocular dominance were dependent on the amount and direction of the prism induced deviation; however, regardless of the type of prisms worn, the kittens which demonstrated interocular misalignments were esotropic.
Treatment of pregnancy hypertension with prostacyclin.
Explore the source record for details and available documents.
Pelvic fluid at ovulation.
Explore the source record for details and available documents.
Vertical fusional vergence ranges of the rhesus monkey.
Explore the source record for details and available documents.
Short-term group psychotherapy: an adult developmental model.
Explore the source record for details and available documents.
The camptomelic syndrome in two female siblings.
A patient is reported whose only two pregnancies resulted in phenotypically and genotypically female infants with camptomelic syndrome of the long-limbed variety. Both infants died within a few minutes of birth.
Women's attitudes to screening for neural tube defects.
The attitudes of 2254 pregnant and 262 other women to serum alpha-fetoprotein (AFP) screening for neural tube defects (NTDs) were investigated, the former by interview and the latter by questionnaires to which 228 replies were received. Over 97 per cent of the pregnant women wanted to be included in such a screening programme. Ninety-six per cent of other women who completed the questionnaire were in favour of national screening for NTDs but 14 per cent of them were uncertain about the action they would take if the test were positive.
The neonatal acoustic reflex.
Probe tones from 220 Hz to 2 000 Hz were used to measure the static and dynamic acoustic impedance of 44 neonates. Acoustic reflex thresholds to broad band noise were obtained from every neonate tested when employing the higher frequency probe tones. The reflex threshold levels measured are similar to those of adults. The static impedance values are discussed to give a possible explanation of why reflex thresholds cannot be detected using conventional 220 Hz impedance bridges.
Trials with the auditory response cradle III: head turns and startles as auditory responses in the neonate.
The Auditory Response Cradle was used to record neonatal head turn and startle responses. Pure tones of 250 and 1,000 Hz, broad band noise and no-sound controls were presented unilaterally in random order at a level of 90 dB SPL. Clear head turn and startle responses were obtained after the onset of the sound. The frequency of occurrence was highest for the noise. No responses attributable to stimulus off were detected. The response rate for head turn was found to be unaltered by the initial head position but babies lying to the right, generally turned to the right and vice versa irrespective of the side to which the sound was presented. The response latency varied with stimulus. The mean broad band noise and 1,000 Hz pure tone values were 1.7 and 1.9 secs respectively while the 250 Hz results were similar to the 2.4 secs of the controls.
Trials with the Auditory Response Cradle. II--The neonatal respiratory response to an auditory stimulus.
The respiratory response of the neonate to an acoustic stimulus is analysed. It is shown that a response may be indicated by (i) a change in the mean cycle time, (ii) a change in the variability of cycle times, (iii) short or long cycles in the sound-on-period following a regular sequence prior to the stimulus. Responses were found to be independent of the pre-stimulus mean cycle time and variability subject to certain restriction. Decision rules are formulated and applied to the Auditory Response Cradle test results. Good agreement is found between statistical and visual methods of trace analysis.
Carbon dioxide and coronary blood flow: direct effects or consequences of altered dynamics of the systemic circulation.
Explore the source record for details and available documents.
Circulatory responses of the dog to acute isovolumic anaemia in the presence of high-grade adrenergic beta-receptor blockade.
The haemodynamic responses to isovolumic anaemia (dextran-for-blood exchange) were studied in seven dogs pretreated with propranolol 20 mg/kg body weight for 3 weeks. Adrenergic beta-receptor blockade did not prevent significant increases in heart rate (up to 19%). Cardiac output increased by about 20% while systemic vascular resistance decreased by the same proportion. Oxygen extraction increased from 24% to 35% and this was reflected by a decrease in mixed venous PO2 by 1.2 kPa. The modest hyperdynamic response of the circulation to haemodilution in the presence of high-grade adrenergic beta-receptor blockade is in sharp contrast with the large hyperdynamic response that has been reported in its absence and indicates that normal compensatory mechanisms are considerably impaired.