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Biomedical subjects

M J Austin

Publications and source records attributed to M J Austin.

26 records · Page 2Linked to original sources
PubMed1985

The role of serotonergic neurons in dorsal raphe, median raphe and anterior hypothalamic pressor mechanisms.

The role of serotonergic neurons in the dorsal raphe and median raphe in the pressor response to electrical stimulation of these areas, and the contribution of these neurons to the pressor response to serotonin (5-HT) in the anterior hypothalamus-preoptic area (AH/PO) have been studied by the use of local injections of 5,7-dihydroxytryptamine (5,7-DHT), a neurotoxin selective for 5-hydroxytryptamine (5-HT). When blood pressure was recorded in urethane-anesthetized rats, selective lesions of 5-HT-containing neurons in the dorsal raphe nucleus reduced by 60% the pressor response to electrical stimulation (50 Hz, 100-150 microA, 0.3 msec pulse duration) of this nucleus. On the other hand, selective lesion of 5-HT-containing neurons in the median raphe nucleus had no effect on the pressor response to electrical stimulation of this area. Injection of 5,7-dihydroxytryptamine into the anterior hypothalamus/preoptic area resulted in an increased pressor response to the injection of 5-HT (5 nmol) into the lesioned area 10 days later. Furthermore, the destruction of 5-HT-containing neurons in the dorsal raphe nucleus resulted in an enhanced pressor response to the injection of 5-HT (5 nmol) into the anterior hypothalamus/preoptic area, while the destruction of 5-HT-containing neurons in the median raphe nucleus had no effect on the pressor response to the injection of 5-HT (5 nmol) into the anterior hypothalamus/preoptic area. Therefore, it appears that 5-HT neurons in the dorsal raphe nucleus are important in the pressor response to electrical stimulation and are involved in a pressor mechanism in the anterior hypothalamus/preoptic area.(ABSTRACT TRUNCATED AT 250 WORDS)

5,7-Dihydroxytryptamine↗
PubMed1978

Social work consultation to nursing homes: a study.

This is a study of 39 social work consultants to nursing homes in the Southeast who continued their consultation activities after the federal government removed the requirement for nursing homes to employ social work consultants to qualify for reimbursement of cost through federal programs. It examines their knowledge and attitudes about aging and their consultative skills in relation to case, process, and program consultation and three types of group work.

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PubMedDate not supplied

The sub-acute center: a proposal for relocating elderly mental patients.

Both researchers and practitioners have become increasingly concerned with the plight of elderly mental hospital patients who are often inappropriately confined in state hospitals and then discharged from these facilities with little preparation for survival or attention given to the quality of community resources. This paper proposes the establishment of a new community care setting, a sub-acute center (SAC), which is designed to meet present inadequacies in the mental care system for the aged and combines elements of a foster home and a protective setting with a mental health aftercare component for more effectively preparing the elderly for independent community living. The SAC combines at least three concepts which are discussed: (a) the receiving station; (b) continuity of care; and (c) advocacy. The professional SAC staff and aides have many potential roles to play as practitioners, spokesmen, educators, consultants, and researchers.

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