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Biomedical subjects

M Ishine

Publications and source records attributed to M Ishine.

34 records · Page 2Linked to original sources

Monte Carlo estimates of absorbed dose rate in various tissues and organs.

A computer program based on the Monte Carlo technique was developed for calculation of absorbed dose rate in various tissues and organs. The accuracy of the program was tested by reproducing Berger's values of the specific absorbed fractions for point isotropic sources in water, and a good agreement with those obtained by the moments method was found within an error of several percent. In comparing with experiment and other Monte Carlo results, good agreement was also obtained within the range of statistical error. The absorbed dose rate for an 123I, 124I, 125I, 126I and 99mTc point source and their specific dose constants in various tissues and organs were calculated using this program. This computer program has the mass energy absorption and attenuation coefficients for 69 tissues and organs as a database file, and can be extended to various radionuclides used in nuclear medicine by adding their nuclear data to the program.

Humans↗

Individual renal function study using computed tomography.

Using computed tomography, the renal parenchymal volume and tissue-plasma ratio of contrast enhancement, with a bolus injection, were measured, and the latter measurement is believed to indicate regional renal function per unit of parenchymal volume. 67 studies were carried out on 50 patients, 17 of whom were examined pre- and postoperatively. Of these 50 patients, 27 had hydronephrosis, 6 had renovascular disease, 4 had pyelonephritis and the remaining 13 were control patients. The product of tissue-plasma ratio of contrast enhancement and the calculated renal parenchymal volume were found to be in good correlation with the individual renal function measured with 99mTc-dimercaptosuccinic acid and 131I-hippuran. Since this method is reproducible, the kidney being examined may be seen in more detail.

Creatinine↗

Gallium-67 citrate scintigraphy in Wegener's granulomatosis involving the stomach.

67Ga-citrate scintigraphy was performed on a 68-year-old woman with Wegener's granulomatosis of the right orbita and nasal cavity to search for other involved sites. Seventy-two-hour images demonstrated an abnormal accumulation on the left upper abdomen, in addition to her head and chest. Upper gastrointestinal series revealed marked deformation of the upper part of the stomach and a large shallow ulcer on its posterior wall. The histological diagnosis from biopsied specimens on gastroendoscopy was an involvement of Wegener's granulomatosis. 67Ga-citrate scintigraphy was helpful in detecting the sites of involvements of this disease.

Aged↗

Carcinoma of the esophagus simulating "downhill" varices.

A case of esophageal carcinoma which showed an upper mediastinal mass shadow on plain chest X-ray film and varicoid lesions on esophagogram is reported. The findings seemed compatible with "downhill" varices, an unusual form of esophageal varices caused by superior vena caval obstruction. In this case, contrast-enhanced computed tomography (CE-CT) was useful for the differential diagnosis between varices and varicoid tumor.

Carcinoma↗