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Biomedical subjects

M Imhof

Publications and source records attributed to M Imhof.

84 records · Page 5Linked to original sources

[New therapeutic aspects in the treatment of diffuse peritonitis].

The diffuse peritonitis is a syndrome during the course of which biochemical reactive chains are activated according to a cascade principle. Most of these biochemical reactive chains develop within an acid environment. The solutions applied for abdominal lavage so far had neutral pH value. The present acute peritonitis experiment has shown that a peritoneal pH increase during lavage therapy stopped the septic reactive chain and thus improved significantly the rate of survival in the test animals. These experimental findings ar now subject for clinical examination.

Animals↗

[Mixed freeze preserved heterologous/autologous full-thickness transplants following 3d degree burns in animal experiments].

On five minipigs third-degree burns were applied. The surgical skin coverage was established after escharectomie by freeze-preserved heterological/autological intermingled full-thickness skin grafts. The freeze-preservation of the Makaka-skin (full-thickness skin) was achieved in a commercially available freezer at -27 degrees C. We could not observe a accelerated or even complete re-epithelialization as it is described in the Chinese papers. The burnwunds healt in form of scare areas covering about half of the previously burned area.

Animals↗

[Idiopathic intestinal pseudo-obstruction].

The extremely rare case of an idiopathic chronic intestinal pseudo-obstruction is pointed out here. This disease would manifest myomechanically by highly active, uncontrollable, non-propulsive contraction. It is caused by a collapse of smooth muscle control with cholinergic and beta adrenergic receptors being partially blocked, and by lacking reaction to substances which act on smooth muscles.

Adult↗

Acute acalculous cholecystitis complicating trauma: a prospective sonographic study.

Acute acalculous cholecystitis (AAC) is a well known complication in severely traumatized patients. Existing data of AAC originate from retrospective analyses and episodic case reports. In a prospective study 45 polytraumatized patients admitted to our intensive care unit from January 1989 to June 1990 were clinically and sonographically screened for this condition at defined time intervals. Trauma scoring was performed according to the injury severity score and polytrauma score. AAC was defined as a combination of hydrops of the gallbladder, an increased wall thickness (> 3.5 mm), and the demonstration of sludge. We were able to document this diagnostic triad in 8 (18%) of 45 patients. As a consequence early elective cholecystectomy was performed in 1 of the 8 patients. The remaining patients were treated conservatively. The incidence of AAC in severely traumatized patients is higher than figures so far published suggest. Ultrasound is a reliable method of early detection and follow-up of this complication.

Acute Disease↗

Acute acalculous cholecystitis in severely traumatized patients: a prospective sonographic study.

Acute acalculous cholecystitis is a well known complication in severely traumatized patients. Existing data originate from retrospective analyses and episodic case reports. In a prospective ultrasonographic study 25 polytraumatized patients admitted to our intensive care unit between January 1, 1989, and December 31, 1989, were examined in daily intervals for this condition. Trauma scoring was performed according to the injury severity score (ISS) and polytrauma score (PTS). "Stress cholecystitis" was defined as a combination of hydrops of the gallbladder, an increased mural thickness (> 3.5 mm), and the demonstration of "sludge." We were able to demonstrate this diagnostic triad in four out of 25 patients (= 16%). As a consequence early elective cholecystectomy was done in one patient. The remaining patients were treated conservatively. The incidence of stress cholecystitis in severely traumatized patients is probably higher than figures so far published suggest. Ultrasonography is a reliable method of early detection and follow-up for this complication.

Acute Disease↗

[Thread design of screw-in acetabulum prostheses].

INTRODUCTION AND AIM OF STUDY: The screw-in behaviour and correct positioning of threaded cups is largely determined by the design of the thread. Up to now the various thread designs have not been systematically classified. METHODS: The thread designs of 10 first generation and 27 second generation threaded cups were analyzed using a tool setter and a no-touch light section technique. The following parameters were evaluated: thread shape, pitch, number of turns, rows of teeth, tooth length and shape. RESULTS: Threads of the first generation were V-cut or saw shaped. Thread depth was 3.1 mm on average; the mean width was 0.9-3 mm. Single-thread patterns predominated. The number of turns ranged from 1-7; the pitch was from 2.5-5 mm (single thread), or up to 20 mm (triple and quadruple threads). Cups had 3-16 rows of teeth. Threads of the second generation are V-cut, saw or flat shaped. Thread depth is 3 mm on average; mean width ranges from 0.3-2.2 mm. 72% of the threads have single-thread patterns. The number of turns ranges from 2-5; the pitch is from 2.5-6.2 mm (single thread). Cups have 4-24 rows of teeth. CONCLUSIONS: There are many different thread patterns with widely varying parameters. Contemporary threaded cups have a narrow V-cut and saw shaped threads or flat thread with depths up to 3 mm, no more than 5 turns, and pitch values of approx. 4.5 mm.

Acetabulum↗