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Biomedical subjects

M Imbriani

Publications and source records attributed to M Imbriani.

At least 73 records · Page 4Linked to original sources
PubMed1984

n-Hexane urine elimination and weighted exposure concentration.

The concentration of n-hexane in urine was determined in 30 subjects occupationally exposed to n-hexane (median value 59.6 mg/m3) in a shoe factory. The measurement of the substance was performed by means of a Hewlett-Packard 5880 gas chromatograph supplied with a Hewlett-Packard 5970 Mass Selective Detector. The analyses were performed by the head space method (constant volume method, after determination of the urine partition coefficient by the multiple phase equilibration method). The authors found a significant correlation between the n-hexane urine concentrations (microgram/l, Cu) and the n-hexane environmental concentrations (mg/m3, Ci) (r = 0.84; Cu = 0.0669 X Ci + 0.8396).

Adult↗
PubMed1984

Determination of plasmatic copper and zinc in uncomplicated pregnancies.

The copper and zinc plasmatic concentrations were determined in a group of 50 pregnant women and in a control group. We found higher copper and lower zinc plasmatic levels in pregnancy than in control group. No correlation was found between the copper and zinc plasmatic levels and the weeks of pregnancy.

Adult↗
PubMed1983

[An open system for exposure to noted and controlled concentrations of aeriform substances].

The AA describe the realise of an open circuit exposure chamber: it enables to reach solvent concentration levels that are continuously monitored and kept within the limits of acceptability. The room can be employed in studies and experimental researches on the respiratory absorption levels of airborne pollutants in man. The following data are reported: on microclimatic parameters, on the monitoring of CO2 concentration in the room when someone is inside, on the solvent concentration measures in different points of the room, on the monitoring of the quickness to reach the steady-state and wash-out in the room, on the available concentration ranges.

Acetone↗
PubMed1983

[Measurement of the coefficient of solubility of airborne substances in blood. II. Solvents of wide industrial use].

A list of industrial solvents largely employed and produced in Italy (and somewhere else too) is presented. Using two methods previously described, blood/air partition coefficient of such solvents have been measured. Then a discussion is made about the possibility of their employment in the field of biological monitoring of subjects professionally exposed to solvent vapours.

Acetates↗
PubMed1983

[The measurement of the solubility coefficients of gases in the blood. III. Other solvents of toxicological importance].

Solubility coefficients of 21 organic industrial solvents of toxicological importance are presented. Using a multiple phase equilibration method, blood/air partition coefficients (lambda) of such substances have been measured. The lambda-values proposed can be employed in the field of biological monitoring of subjects professionally exposed to solvent vapours.

Environmental Exposure↗
PubMed1982

[The "peripheral factor" in muscular exertion].

On the basis of their own experimental results and of those from the literature, the Authors have studied the possibility of bloodless evaluation of the ratio: oxygen extraction (DAV) to total peripheral resistances (TPR). The so called "peripheral factor" which can be thus obtained (units: m10(2) X min-1 X mmHg-1), appears to be a sensitive index of the metabolic-functional behaviour of skeletal musculature and of the degree of left ventricular involvement during various types of muscular exercise. From resting value of 3-5, the "peripheral factor" can increase up to 40 m10(2) X min-1 X mmHg-1 in well trained athletes, and it appears to be influenced not only by the amount of work performed but also by the "type" of muscle group involved.

Blood Pressure↗
PubMed1982

[Changes in hemodynamic and metabolic parameters during controlled muscular exertion in a group of international-level professional cyclists].

The behaviour of some cardiovascular and metabolic parameters have been studied in 11 competitive road-cyclists under controlled submaximal work load. The test used was intermittent with load increasing from 100 to 250 watt, independent from age and body weight of the athletes. The results obtained have shown that whereas the estimated VO2 was 4,76 LO2/min, the extrapolated VO2max goes up to 6,08 LO2/min, corresponding to 84,55 m102/Kg X min. Particularly interesting seems to be the way through which the high VO2 levels can be obtained in these subjects: small increment of the mean arterial blood pressure together with large oxygen extraction and high vasodilatation.

Adult↗
PubMed1982

[Evaluation of a new alveolar air sampler].

A new alveolar air sampler is described and tested; it can be used in monitoring subjects exposed to gas and vapours in their working places. The tests were made under different experimental conditions, using both vapours of industrial solvents as acetone, ethanol, trichloroethylene, methyl ethyl ketone, n-hexane, ethyl acetate and respiratory gas (O2, CO2).

Acetone↗
PubMed1980

[Modifications of some cardiorespiratory parameters under a controlled work-load in a group of football players, winners of Italian championship football].

The modifications of some cardiorespiratory and metabolic parameters in 18 football players under controlled work-load has been investigated. The results obtained show that by increasing work-load VO2, HR, VE, RR, TV and VA also linearly increase; FiO2-FeO2 steeply increases at he reduced work-load (50 Watt) while at the higher loads (from 100 to 200 Watt) grows with less steep slope. The oxygen consumption evaluated at 200 Watt shows a figure of 50 ml O2/min/Kg, whereas the maxim calculated VO2 goes up to 75,56 ml/min/Kg body weight.

Adult↗
PubMed1980

Immunological parameters in farmers with chronic lung disease.

The serum concentrations of IgG, IgA, IgE, C3 (B1A), C4 and alpha 1 AT were measured in 8 farmers with chronic pneumopathy, who showed precipitins against M. faeni or T. vulgaris in the serum. A group of 8 precipitins negative farmers who had worked in barn and 28 normal subjects served as control. IgG were elevated in the patients with detectable precipitins; levels of serum IgA in patients with precipitating antibody were lower than in the subjects without them. The mean levels of C3 were significantly lower in the farmers with detectable precipitins than in the farmers without precipitating antibody and in the control group.

Adult↗
PubMed1979

[Determination of plasma chromium in pregnant women at term and in the umbilical cord blood].

Plasma chrome concentrations were determined in pregnant women, in the funiculus blood of their children and in a population of a children within the first year age. Plasma chrome concentrations tend to significantly decrease during pregnancy, pointing out the effect of pregnancy on chrome metabolism. No significant variations were found in plasma chrome values both of mother blood and foetus blood. In newborn babies, plasma chrome concentrations tend to significantly increase within the first year of age.

Adult↗
PubMed1975

[Measurement of "flow-volume" curves and "closing volume" in occupational medicine. Normal findings in healthy subjects (author's transl)].

A method is described for measuring, by a single test, some functional respiratory indexes, such as lung volumes, dynamic tests (flow-volume curve included), rapid He and CO2 curves, "closing volume". The normal values of "closing volume" and of forced expiratory flows obtained in 114 healthy subjects (65 men and 49 women) are then reported. Such values are comparable to those obtained by other authors. An equipment is used by the authors which is easily transportable to the workplace; their method can therefore be used for surveys of workers exposed to occupational respiratory risk during a working shift. The described respiratory index should be able to detect in a pre-clinical stage the early functional changes in chronic bronchitis.

Adult↗
PubMedDate not supplied

Effects of dimethylformamide (DMF) on coagulation and platelet activity.

The effects of dimethylformamide (DMF) on hemostatic functions, especially on platelet activity, were examined both in vitro and in vivo in 15 workers exposed to DMF (27 mg/m3, median value). Twenty-eight control subjects who were not exposed to DMF, but comparable for age, anthropometric data, and smoking habits, were also studied. Workers exposed to DMF showed a decrease in the number of platelets and had longer coagulation times, probably due to a change caused by DMF on the membrane receptor of platelets and on the phospholipid components of the clotting system.

Adenosine Diphosphate↗
PubMedDate not supplied

Urinary excretion of tetrachloroethylene (perchloroethylene) in experimental and occupational exposure.

Fifteen human volunteers were exposed to tetrachloroethylene (perchloroethylene, tetrachloroethene) vapor at 3.6-316 mg/m3 for 2-4 hr at rest (10 cases) and during light physical exercise (5 cases). Subsequently, 55 workers who were occupationally exposed to tetrachloroethylene in eight commercial dry cleaning facilities were studied (median value, 66 mg/m3; geometric standard deviation, 3.15 mg/m3). In both the experimentally exposed subjects and occupationally exposed workers the urinary concentration of tetrachloroethylene showed a linear relationship to the corresponding environmental time-weighted average concentration. The findings indicate that the urinary concentration of tetrachloroethylene can be used as an appropriate biological exposure indicator. In occupationally exposed subjects performing moderate work, the urinary tetrachloroethylene concentration corresponding to the time-weighted average of the threshold limit value proved to be 120 mcg/L and its 95% lower confidence limit (biological threshold) 100 mcg/L. The effects of workload on the tetrachloroethylene urinary elimination are also accounted for.

Adult↗
PubMedDate not supplied

Biological monitoring of occupational exposure to enflurane (ethrane) in operating room personnel.

Biological monitoring of occupational exposure to enflurane (ethrane) can be achieved by measuring concentrations of inorganic fluorides in the blood and urine and of enflurane in alveolar air and venous blood. Measurement of these concentrations, however, has limitations. Another method for monitoring exposure to enflurane is to measure its concentration in urine throughout the period of exposure. In this study, we measured the environmental and urinary concentrations of enflurane. Enflurane in the ambient atmosphere was determined in 18 operating theaters of eight hospitals in Italy. Ambient air concentrations exceeded the National Institute for Occupational Safety and Health-recommended time-weighted average exposure level of 1 ppm (median: 1.31 ppm). Enflurane was detected in urine of 159 exposed subjects (anesthetists, surgeons, and nurses). A significant correlation was found between enflurane concentration in urine produced during the shift and environmental concentration (r = 0.77, p = .0001). The results showed that urinary enflurane concentration can be used as an appropriate biological exposure index. The biological values proposed are 153 micrograms/l, corresponding to 75 ppm of environmental exposure; 22 micrograms/l, corresponding to 10 ppm of environmental exposure; and 3.5 micrograms/l, corresponding to 1 ppm of environmental exposure. The proposed values can be regarded as time-weighted average samples, reflecting exposure for a 4-h period.

Adult↗