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Biomedical subjects

M Ia Ruda

Publications and source records attributed to M Ia Ruda.

At least 91 records · Page 5Linked to original sources

[Comparative characteristics of the physical, x-ray and hemodynamic data in assessing heart failure in myocardial infarct].

The physical and X-ray findings in 103 patients with acute myocardial infarction were compared with the value of left-ventricular filling pressure (LVFP). The LVFP was determined from the level of end diastolic pressure in the pulmonary artery determined by means of a balloon catheter. On the whole, the congruence was revealed between the X-ray findings and the LVFP. A still more definite picture may be obtained of the LVFP value if the results of physical examination are considered in addition to the X-ray data. At the same time, a disparity arises in some cases between the information obtained by means of catheterization of the pulmonary artery on the one hand and the physical and X-ray methods on the other. This must be borne in mind in applying intensive therapeutic measures, e. g. in cases with acute left-ventricular insufficiency, because erroneous therapeutic tactics may be chosen due to "post-therapeutic delay" of the physical and X-ray symptoms.

Adult↗

[Use of vasodilator agents for treating acute cardiac insufficiency].

Peripheral vasodilators nitroglycerin and sodium nitroprusside were given to 29 patients in the treatment of acute circulatory insufficiency (10 of these patients had pulmonary edema) which in most of them was caused by acute myocardial infarction. Diastolic pressure in the pulmonary artery, which was measured by means of a Swan-Ganz balloon catheter, was above 18 mm Hg (18--34 mm Hg) in all patients. Sodium nitroprusside and nitroglycerin given sublingually caused rapid normalization of diastolic pressure in the pulmonary artery and reduction of arterial pressure with no essential changes in the rate of cardiac contractions and cardiac output, which was attended by an improvement in the functional condition of the left ventricle and in the patients' condition. In patients with a low initial cardiac output (less than 2.2 1/min/m2), however, there was a statistically significant increase of this index in the presence of sodium nitroprusside administration. It is advisable to use sodium nitroprusside for long-term treatment of cardiac insufficiency in a low cardiac output, whereas nitroglycerin is a good measure for rapid relief of pulmonary congestion.

Acute Disease↗

[Physician's approach in treating myocardial infarct complicated by a transverse heart block].

On the basis of the results of observation over 253 patients in whom the acute period of myocardial infarction was complicated by atrioventricular block, the author recommends the therapeutic tactics in this group of patients. It is shown that electrical stimulation is the most effective method of treatment in complete atrioventricular block. Analysis of the natural course of atrioventricular block in myocardial infarction shows that the artificial pacemaker should be implanted not earlier than 4 weeks after the development of the block, if the block does not disappear by that time. Data on the condition of circulation obtained by means of the routine physical methods of examination are the most valuable criteria in the choice of the ortimum parameters of electrical stimulation of the heart.

Adams-Stokes Syndrome↗

[Variants of hemodynamic changes in acute period of myocardial infarct and the importance of their detection for treatment].

Sixty-three patients suffering from acute myocardial infarction were examined within the first 24 hours of the disease (27 within the first 6 hours) by means of catheterization of the right parts of the heart with a Swan-Ganz balloon catheter and thermodilution. Comparison between the cardiac output and the pressure of left ventricular filling allowed the following hemodynamic variants of myocardial infarction to be distinguished: normo-, hypokinetic, with increased pressure of left ventricular filling and normal cardiac output, hypovolemic, and hyperdynamic. The results of the tests with acute rheopolyglucin load (9 patients) showed that some of the patients with normal values of hemodynamics had latent cardiac insufficiency. Hemodynamic study and recognition of the variant of hemodynamic changes in the acute period of myocardial infarction made it possible to determine properly the indications for the use of vasodilators, active inotropic agents, and infusion therapy.

Acute Disease↗

[Myocardial scintigraphy in the diagnosis of infarct in patients with disorders of intraventricular conduction].

Myocardial scintigraphy with pyrophosphate-99mTc-Sn was used as a diagnostic test in 23 patients with different disorders of rhythm and intracardia conduction who were admitted to the department of emergency cardiology of the All-Union Cardiological Scientific Center, Academy of Medical Sciences of the USSR with suspected acute myocardial infarction. Scintigrams were positive in 11 of 12 patients with acute myocardial infarction who were examined in periods of 6 hours of 10 days. One patient examined on the 13th day of the disease had negative scintigrams. In 6 of 11 patients with myocardial infarction not confirmed, the scintigrams were also negative, in 3 other patients positive scintigrams were due to a postinfarction aneurysm. The authors conclude that myocardial scintigraphy with pyrophosphate-99mTc-Sn is an adequate test in the diagnosis of acute myocardial infarction, especially in the examination of patients with disorders of intracardiac conduction.

Aged↗

[Effect of strophanthin and atropine on atrioventricular conduction in acute myocardial infarct].

The effect of single therapeutic doses of strophanthin (0.25--0.4 mg) and atropine (0.75--1,0 mg) on cardiac contraction was studied in 39 patients with acute myocardial infarction and in 12 subjects with no signs of organic heart affection by recording the electrical potentials of the heart conduction system. The indicated dose of strophanthin caused changes in the intervals of the electrogram neither in individuals who did not have myocardial infarction nor in patients with acute myocardial infarction, including those with myocardial infarction complicated by atrioventricular and intraventricular block. Atropine improved atrioventricular conduction by shortening the PH interval in patients with myocardial infarction complicated by I--II grade atrioventricular block and had no marked effect on the spread of excitation impulses along the atrioventricular node in higher grades of atrioventricular block. Atropin shortened the PH interval slightly in individuals without myocardial infarction and in patients with uncomplicated myocardial infarction, but did not have an effect on intraventricular conduction.

Acute Disease↗

[Hemodynamics in atrioventricular block in acute myocardial infarct and its changes under the influence of electric stimulation of the heart].

Hemodynamics was studied in the initial condition and against the background of electric stimulation of the heart in 18 patients with acute myocardial infarction complicated by complete atrioventricular block. It is shown that block promotes the development of circulatory insufficiency in patients with myocardial infarction. The marked character of hemodynamic disorders and the changes induced in it by electric stimulation are determined in many respects by the functional condition of the left ventricle. In most patients with acute myocardial infarction complicated by complete atrioventricular block, with the exception of those with a clinical picture of cardiogenic shock, the main values of hemodynamics demonstrated against the background of electric stimulation hardly differ from the corresponding values in patients with myocardial infarction and no disturbances of atrioventricular conduction. During electric stimulation of the heart in the contingent of patients examined, the external work of the heart and the "tension/time" index considerably increase which suggests a marked increase in the myocardium requirements in oxygen. The probability of unbalanced increase in the requirements of the myocardium in oxygen against the background of electric stimulation dictates the necessity for raising its parameters to optimum levels.

Acute Disease↗

[P-controlled electrical heart stimulation in complete transverse block in acute myocardial infarct].

The article discusses the results of the comparative study of certain hemodynamic indices in patients with myocardial infarction complicated by complete atrioventricular block, during routine electric stimulation of the ventricles and during P-controlled electric stimulation of the ventricles. Changes in hemodynamics were more marked in the last case, but only the values of the minute cardiac volume and of central venous pressure were found to differ substantially in these two groups. The authors presume that such a hemodynamic situation may occur in myocardial infarction in which P-controlled electric stimulation will produce more essential changes in hemodynamics that those induced by routine electric stimulation. Synchronized electric stimulation may be more preferable in such cases.

Blood Pressure↗

[Optimal frequency for electrical stimulation of the heart in transverse block in acute myocardial infarct].

Study of hemodynamics did not disclose any sole criterion for determining the optimum frequency of electric stimulation of the heart in the IV degree atrioventricular block in patients with acute myocardial infarction. Only a complex of indices serves the purpose, among which the first and foremost is the patient's general condition appraised by means of the routine physical methods and, whenever possible, by measuring the cardiac minute volume and the central venous pressure. The necessary frequency of electric stimulation in the prevention of arrhythmia should be chosen empirically.

Acute Disease↗

[Certain methodological problems of the use of temporary electric stimulation of the heart in disorders of atrio-ventricular conductivity in patients with acute myocardial infarct].

Some methodical problems are discussed that are of practical importance for the performance of transvenous endocardial pacing of the heart in patients with acute myocardial infarction in whom the clinical course is complicated by an atrio-ventricular block. Some results of the employment of this method in 66 cases of acute myocardial infarction are presented. A set of criteria is suggested for controlling the proper position of the probe in the cardiac cavity, the most important approaches for the introduction of the probe are described, as well as the main reasons of ineffective cardiac pacing and its most common complications.

Adult↗