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Biomedical subjects

M I Timofeeva

Publications and source records attributed to M I Timofeeva.

8 recordsLinked to original sources
PubMed1990

[Biomechanical evaluation of the functional state of the locomotor system and the effectiveness of surgical treatment of children with Legg-Perthes disease].

For the first time in the patients with Perthes' disease (stages II-III) the authors have evaluated the functional state of the locomotor system in dynamics on the basis of a complex study which included a roentgenobiomechanical analysis of the loads on the hip joint (39 children) after F. Pauwels technique (1959), radio pelvimetry (75 children) after Kh. Z. Gafarov et al. (1984) and biomechanical and electromyographic (36 children) in the static position and during walking. The results obtained have allowed to make a substantial contribution into the characteristics of the functional state of the hip joint in Perthes' disease and to make an objective evaluation of the efficacy of the surgical treatment consisting in using new methods with the aim of decompression and distraction on the basis of not only anatomic but also functional and biomechanical criteria of evaluation.

Child↗
PubMed1989

[Outcome of decompression operations in the treatment of Legg-Perthes disease].

The authors evaluate the results of 90 decompression operations in 68 patients with Perthes' disease at stages I-IV; the mean age of the children was 8.3 +/- 1.2 years and the follow-up period after the surgery was from 6 months to 10 years. Decompression operations made in the clinic have been protected by author's certificates No. 942712 and No. 1050672. The results were excellent and good in 87.8% and satisfactory in 12.2%. Decompression operations are substantiated from the pathogenetic viewpoint. They interrupt the pathologic process in the epiphysis, contribute to a rapid restoration of the femoral head, are characterized by low traumatism and may be performed simultaneously on both sides which precipitate the children's rehabilitation. The best results have been observed in the children aged 5 to 7 years and at stages I and II of the disease. The surgical treatment has allowed to reduce the terms of the treatment of the children 3 to 4-fold as compared with the conservative method.

Adolescent↗
PubMed1979

[Bone tissue dystopy].

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Bone Diseases, Developmental↗
PubMedDate not supplied

[Detection and several characteristics of leach genome palindromes].

About 5% of the loach (Misgurnus fossillis L.) DNA reassociates at Cot values virtually equal to zero. 50% of the reassociate are resistant to nuclease S1 treatment and reveal the properties of double-stranded structure when chromatographed on hydroxyapatite. Some proofs of palindromic (hair-pin) nature of this fraction have been obtained. An introduction of nicked scissions into the palindromic DNA by pancreatic DNAse treatment under pessimal conditions made it possible to investigated reassociation kinetics of the nucleotide sequences forming palindromes. Two different types of nucleotide sequences appeared to exist in the palindromic fraction with repetition frequencies (ni) equal to 3 X 10(2) and about 1. Homologies were revealed between these sequences and the fraction of corresponding repetition frequency of the main part of the genome. Adjacent sequences contain repetitive regions with ni equal to 10(5) and 5 X 10(3). On the basis of the data obtained some conclusions were made about the distribution of usual and inverted repetitions in the loach genome.

Animals↗